Results 51 to 60 of about 28,155 (204)

Differential pharmacology and clinical utility of rolapitant in chemotherapy-induced nausea and vomiting

Cancer Management and Research, 2017
Bernardo Leon Rapoport The Medical Oncology Centre of Rosebank, Johannesburg, South Africa Abstract: Chemotherapy-induced nausea and vomiting (CINV) is a debilitating side effect of many cytotoxic chemotherapy regimens.
Rapoport BL
doaj  

Incidence of Post-Sedation Emesis in Cynomolgus (Macaca fascicularis) and Rhesus (Macaca mulatta) Macaques, and Evaluation of Prophylactic Antiemetic Efficacy

Animals
Emesis is one of the most common side effects of ketamine sedation; however, predictors like species and sex have not been studied in macaques. This study aimed to determine the incidence and predictors of emesis in macaques undergoing ketamine sedation ...
Rachel Coley, Sierra D. Palmer, Jennifer Hubbard, Melanie L. Graham   +3 more
doaj   +1 more source

A comparison of the upright seated versus left lateral decubitus position during pediatric sedation‐free transnasal endoscopy

JPGN Reports, EarlyView.
Abstract Objectives Although sedation‐free transnasal endoscopy (TNE) is conventionally performed in an upright seated position in pediatric patients, emerging data suggest that the left lateral decubitus (LLD) position may improve both endoscopic visualization and patient comfort and safety.
Catherine Nguyen, Molly Mackensen, Sophie Branen, Katherine Vaidy, Rose Lee   +4 more
wiley   +1 more source

Cyclic vomiting syndrome: diagnostic approach and current management strategies

Clinical and Experimental Gastroenterology, 2018
William J Hayes,1 Deidra VanGilder,2 Joseph Berendse,3 Michael D Lemon,3 John A Kappes4 1Department of Pharmacy Practice, South Dakota State University, Regional Health Medical Clinic, Rapid City, SD, USA; 2South Dakota State University, College of ...
Hayes WJ, VanGilder D, Berendse J, Lemon MD, Kappes JA   +4 more
doaj  

Laryngeal Cryotherapy for Neurogenic Cough: Safety, Feasibility, and Prospective Outcomes

The Laryngoscope, EarlyView.
A prospective clinical trial investigated the safety and clinical outcomes of office‐based selective laryngeal cryotherapy for patients with refractory chronic cough. Patient were followed for 6 months posttreatment and had durable improvement in cough severity index and urge‐to‐cough scores and no serious long term adverse effects.
Shumon I. Dhar, Eric Allen, Yun‐Lun Liu, Alexandra D. D'Oto, Rishi Suresh, Adrianna Shembel, Ted Mau   +6 more
wiley   +1 more source

Yearly incidence of acute childhood gastroenteritis in Nigeria: Implicated pathogens predominantly harbor blaCTXM and blaTEM genes

Journal of Infection in Developing Countries
Background and Objectives: Routine use of antibiotics for infectious diarrhea in children is associated with the risk of increasing antibiotic resistance in developing countries. This work aimed to study the predominant extended spectrum beta-lactamase (
Ebuka Elijah David, Ikechuku Okorie Igwenyi, Ifeanyichukwu Romanus Iroha, Eghosa Lucky Emumwen, Christian Emmanuel Offor, Okechukwu Jerry Orji, Franklyn Chinwe Igwe, David Chukwu Obasi, Jeff Onochie Nkama, Boniface Oke, Moses Eji Ogbanshi   +10 more
doaj   +1 more source

Superior Hypogastric Nerve Block in Uterine Artery Embolisation Protocols for Symptomatic Fibroids: An Australian Single‐Centre Experience

Journal of Medical Imaging and Radiation Oncology, EarlyView.
ABSTRACT Introduction Assessment of the safety of Superior Hypogastric Nerve Block (SHNB) in uterine artery embolisation (UAE) for symptomatic fibroids. Method Retrospective single tertiary centre analysis of patients who underwent UAE with SHNB (n = 40). Outcomes include assessment of pain scores, overnight stays and complications.
Nessa Kellegher, Jonathan Kelly, Gillian Kehoe, Kevin Ho, Gurjeet Dulku   +4 more
wiley   +1 more source

Safety pharmacology of acute mescaline administration in healthy participants

British Journal of Clinical Pharmacology, EarlyView.
Aims Psychedelics, including mescaline, may serve as novel treatments for depression and anxiety. However, data is scarce on the safety of mescaline. Methods The present pooled analysis included two double‐blind, randomized, placebo‐controlled studies with a total of 48 participants and 96 mescaline administrations. Single oral‐dose administrations (n =
Aaron Klaiber, Mélusine Humbert‐Droz, Laura Ley, Yasmin Schmid, Matthias E. Liechti   +4 more
wiley   +1 more source

Amylin analogues as a novel perspective in anti‐obesity therapy

British Journal of Pharmacology, EarlyView.
Abstract Public health systems face a major challenge because of the worldwide obesity epidemic. The number of obese individuals has increased dramatically and, even in Switzerland which may be considered a relatively “lean” country, the numbers are alarmingly high and have reached almost 50% of the adult population.
Thomas A. Lutz
wiley   +1 more source

Therapeutic access points: The roles of circumventricular organs in drug delivery and metabolic regulation

British Journal of Pharmacology, EarlyView.
The current obesity drug landscape, dominated by GLP‐1 receptor agonists and emerging multi‐agonist therapies, has reinforced that long‐term weight loss is achieved in large part through central mechanisms that suppress appetite and reshape energy balance.
Ines Martinez‐Corral, Nicholas Monaco, Daniel I. Brierley, Monica Imbernon   +3 more
wiley   +1 more source