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Current Medical Research and Opinion, 2000
Nausea and vomiting are common symptoms of migraine, which can be controlled with a variety of anti-emetics including phenothiazines and antihistamines. Metoclopramide and domperidone have an additional prokinetic effect which may be important in migraine to overcome gastric stasis and enhance absorption of oral medication.
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Nausea and vomiting are common symptoms of migraine, which can be controlled with a variety of anti-emetics including phenothiazines and antihistamines. Metoclopramide and domperidone have an additional prokinetic effect which may be important in migraine to overcome gastric stasis and enhance absorption of oral medication.
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Expert Opinion on Investigational Drugs, 2002
Despite important advances in pharmacotherapeutic options for the prevention and treatment of nausea and vomiting during the 1990s, a significant proportion of patients still suffer debilitating nausea and vomiting symptoms. The most problematic areas are chemotherapy-induced nausea and vomiting particularly delayed emesis, postoperative nausea and ...
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Despite important advances in pharmacotherapeutic options for the prevention and treatment of nausea and vomiting during the 1990s, a significant proportion of patients still suffer debilitating nausea and vomiting symptoms. The most problematic areas are chemotherapy-induced nausea and vomiting particularly delayed emesis, postoperative nausea and ...
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Emetics and antiemetics are two classes of medications that serve opposite purposes in managing nausea and vomiting. Emetics, such as ipecac syrup, induce vomiting and are used primarily in certain poisoning cases to expel ingested toxins from the stomach. However, their use has declined due to the potential risks and the availability of more effective
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Marijuana: Anti-Emetic or Pro-Emetic?
American Journal of Gastroenterology, 2012Ana Maria Crissien Martinez, Emily Singh
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Advances in anti-emetic therapy
Cancer Treatment Reviews, 1984Evaluation of the activity of anti-emetic drugs in randomized controlled trials has, in most cases, demonstrated the superiority of treatment over placebo administration for the control of chemotherapy-induced emesis (see Table 15). The degree of control of emesis relates both to the intensity of the emetogenic stimulus and to the effectiveness of the ...
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Methodology in Anti-Emetic Trials
Oncology, 1992The most promising anti-emetic drugs are identified during preclinical testing. Phase I and II clinical studies are used to optimize doses and schedules for the various routes of administration. Most methodological issues arise in relation to phase III studies.
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