Results 41 to 50 of about 301,881 (351)

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

Positron emission tomography/computed tomography surveillance in patients with Hodgkin lymphoma in first remission has a low positive predictive value and high costs

Haematologica, 2012
Background The value of performing post-therapy routine surveillance imaging in patients with Hodgkin lymphoma is controversial. This study evaluates the utility of positron emission tomography/computed tomography using 2-[18F]fluoro-2-deoxyglucose for ...
Tarec Christoffer El-Galaly, Karen Juul Mylam, Peter Brown, Lena Specht, Ilse Christiansen, Lars Munksgaard, Hans Erik Johnsen, Annika Loft, Anne Bukh, Victor Iyer, Anne Lerberg Nielsen, Martin Hutchings   +11 more
doaj   +1 more source

Role of ¹¹C-Methionine PET/CT in ^99mTc-Sestamibi-Negative Parathyroid Adenoma: A Case Report

Diagnostics, 2021
We report a case of 16-year-old female primary hyperparathyroidism patient who underwent cervical ultrasonography and 99mTc-sestamibi single photon emission computed tomography/computed tomography, both of which were negative for parathyroid adenoma ...
Jang Yoo, Miju Cheon
doaj   +1 more source

On the data dependent filtration techniques in the single-photon emission computed tomography [PDF]

, 2005
We develop space variant data dependent filtration techniques for single-photon emission computed tomography (SPECT) data modeled as the 2D attenuated ray transform with Poisson noise.
Guillement, Jean-Pol, Novikov, Roman
core   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Quantifying lung growth with CT-derived intrapulmonary vascular volume: a cross-sectional study

BMC Medical Imaging
Background This study aimed to evaluate lung growth by the quantitative assessment of intrapulmonary vascular volume on chest CT images. Methods All 1122 subjects were grouped with a 2-year age span.
Meijuan Shi, Peng Gao, Meng Li, Weili Yang, Nan Yin, Youmin Guo, Cong Shen   +6 more
doaj   +1 more source

LEVELS OF PATIENTS EXPOSURE AND A POTENTIAL FOR OPTIMIZATION OF THE PET DIAGNOSTICS IN THE RUSSIAN FEDERATION

Радиационная гигиена, 2018
This study presents an overview of the most common positron emission tomography examinations in Russia, as well as the acquisition protocols and patient doses.
L. A. Chipiga, I. A. Zvonova, D. V. Ryzhkova, M. A. Menkov, М. B. Dolgushin   +4 more
doaj   +1 more source

Splenosis Mimicking Peritoneal Seeding of Advanced Colon Cancer Can Be Identified by Spleen SPECT/CT and FDG PET/CT

Diagnostics, 2021
This case report demonstrates that Tc-99m labeled heat-damaged red blood cell single-photon emission computed tomography/computed tomography (spleen SPECT/CT) and F-18 fluorodeoxyglucose positron emission tomography/CT (FDG PET/CT) could noninvasively ...
Ji Young Lee, Hee-Sung Song, Jimin Han
doaj   +1 more source

Metastatic cervical paravertebral solitary fibrous tumor detected by fluorodeoxyglucose positron emission tomography-computed tomography. [PDF]

, 2018
Solitary fibrous tumor/hemangiopericytomas (SFT/HPC) are soft tissue tumors that can arising from the abomen, pleura, head and neck, or extremities.
Aparici, Carina Mari, Cheung, Hoiwan, Lawhn-Heath, Courtney, Lopez, Giselle, Vella, Maya   +4 more
core   +2 more sources

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source