Results 1 to 10 of about 38,224 (238)

Recent Advances and Strategies in the Development of Therapeutic Radiopharmaceuticals [PDF]

Journal of Isotopes
Therapeutic radiopharmaceuticals can be employed in the treatment of various tumor diseases，and their global market share is likely to witness an explosive growth in the recent decade.
Mianxue LIU, Yueqi LIANG, Min HUANG, Hao CHEN, Yuxi LUO, Jian ZHAO, Lijuan CHEN, Hongtao JIN, Qian CHEN   +8 more
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Design, Preparation, and Evaluation of a Novel ^99mTcN Complex of Ciprofloxacin Xanthate as a Potential Bacterial Infection Imaging Agent

Molecules, 2020
In order to seek novel technetium-99m bacterial infection imaging agents, a ciprofloxacin xanthate (CPF2XT) was synthesized and radiolabeled with [99mTcN]2+ core to obtain the 99mTcN-CPF2XT complex, which exhibited high radiochemical purity ...
Si’an Fang, Yuhao Jiang, Qianqian Gan, Qing Ruan, Di Xiao, Junbo Zhang   +5 more
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Progress and Prospects of Research and Development ofRadiopharmaceuticals in China

He huaxue yu fangshe huaxue
The research and development of radiopharmaceuticals is very important for the early diagnosis and treatment of major diseases such as heart, brain, and tumors.
Hua-bei ZHANG, Yu FANG
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Novel [99mTcN]2+ Labeled EGFR Inhibitors as Potential Radiotracers for Single Photon Emission Computed Tomography (SPECT) Tumor Imaging

Molecules, 2014
The epidermal growth factor receptor (EGFR) is overexpressed in many cancers, including breast, ovarian, endometrial and non-small cell lung cancer. An EGFR-specific imaging agent could facilitate clinical evaluation of primary tumors or metastases.
Mingxia Zhao, Hongyu Ning, Man Feng, Shilei Li, Jin Chang, Chuanmin Qi   +5 more
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Research Progress of 64Cu-Radiopharmaceuticals in Clinical Trial for Tumor Diagnosis

Journal of Isotopes, 2021
Positron computed emission tomography (PET) is an important diagnosis and imaging tool for nuclear medicine with the advantages of high sensitivity, resolution, and safety.
ZHAO Hailong;LI Hongyu
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Author Correction: Synthesis and comparative evaluation of 177Lu-labeled PEG and non-PEG variant peptides as HER2-targeting probes

Scientific Reports, 2022
Amit Kumar Sharma, Rohit Sharma, Kusum Vats, Haladhar Dev Sarma, Archana Mukherjee, Tapas Das, Drishty Satpati   +6 more
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Non-clinical Studies of Radiopharmaceuticals: Analysis of National and International Regulatory Practice (Review)

Регуляторные исследования и экспертиза лекарственных средств
INTRODUCTION. Currently in the Russian Federation and the Eurasian Economic Union (EAEU), the conduct of non-clinical studies of radiopharmaceuticals is regulated by general guidelines on non-clinical studies, which are applicable to multiple groups of ...
O. E. Klementyeva, A. V. Smirnova, N. Yu. Kulbachevskaya, E. Yu. Grigorieva, Yu. S. Lagodzinskaya, T. G. Gevorkyan   +5 more
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SINTESIS DAN KARAKTERISASI NUKLEOTIDA BERTANDA [α-32P]ATP

Jurnal Riset Kimia, 2019
The utilization of nuclear technology in health sector with molecular techniques is increasingly developed today, especially in Indonesia.  One of which is nucleotide compound marked with [α-32P]ATP, this compound has been used as tracer for ...
Wira Yusril Rahman, Endang Sarmini, H. Herlina, A. Abidin, T. Triyanto, H. Hambali, Santi Nurbaiti   +6 more
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Radiopharmaceutical small-scale preparation in Europe: will we be able to harmonize the situation?

EJNMMI Radiopharmacy and Chemistry
Background Radiopharmaceuticals have been considered a special group of medicines in Europe since 1989. The use of radiopharmaceuticals that have marketing authorization should always be the first option in clinical use, however due to their special ...
Estrella Moya, Celia Cerrato, Luis Miguel Bedoya, José Antonio Guerra   +3 more
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Discovery and evaluation of a novel 18F-labeled vasopressin 1a receptor PET ligand with peripheral binding specificity

Acta Pharmaceutica Sinica B
The arginine-vasopressin (AVP) hormone plays a pivotal role in regulating various physiological processes, such as hormone secretion, cardiovascular modulation, and social behavior.
Junqi Hu, Yinlong Li, Chenchen Dong, Huiyi Wei, Kai Liao, Junjie Wei, Chunyu Zhao, Ahmad Chaudhary, Jiahui Chen, Hao Xu, Ke Zhong, Steven H. Liang, Lu Wang, Weijian Ye   +13 more
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