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Preoperative Imaging of Charcot Neuroarthropathy in Diabetic Patients: Comparison of Ring PET, Hybrid PET, and Magnetic Resonance Imaging [PDF]

open access: yes, 2004
Introduction: The treatment of Charcot neuroarthropathy in the feet of diabetic patients has undergone fundamental changes in the last few years. Formerly, treatment was almost exclusively limited to nonoperative measures; since the late 1990s, however ...
Brinkbäumer, Kirsten   +6 more
core   +1 more source

Lung metastasis and recurrence is mitigated by CAR macrophages, in-situ-generated from mRNA delivered by small extracellular vesicles

open access: yesNature Communications
Cancer metastasis and recurrence remain the leading causes of cancer-related mortality, and lung is a major metastatic anatomical location. Chimeric antigen receptor macrophages (CAR-M) represent promising candidates for cancer therapy owing to their ...
Yuchen Xiao   +3 more
doaj   +1 more source

ZAP's stress granule localization is correlated with its antiviral activity and induced by virus replication. [PDF]

open access: yes, 2019
Cellular antiviral programs encode molecules capable of targeting multiple steps in the virus lifecycle. Zinc-finger antiviral protein (ZAP) is a central and general regulator of antiviral activity that targets pathogen mRNA stability and translation ...
Jurado, Andrea   +6 more
core   +2 more sources

An Atypical Presentation of Cystic Echinococcosis [PDF]

open access: yes, 2020
Cystic echinococcosis (CE) is an infection caused by the Echinococcus granulosus tapeworm. CE generally manifests in the liver, but it may present in any organ. These patients often first present to the emergency department.
Abou Asala, Elian D.   +3 more
core  

Super-Resolution Imaging of Protein Secretion Systems and the Cell Surface of Gram-Negative Bacteria

open access: yesFrontiers in Cellular and Infection Microbiology, 2017
Gram-negative bacteria have a highly evolved cell wall with two membranes composed of complex arrays of integral and peripheral proteins, as well as phospholipids and glycolipids.
Sachith D. Gunasinghe   +4 more
doaj   +1 more source

Galectin-3 induces pathogenic immunosuppressive macrophages through interaction with TREM2 in lung cancer

open access: yesJournal of Experimental & Clinical Cancer Research
Background High infiltration of tumor-associated macrophages (TAMs) is associated with tumor promotion and immunosuppression. The triggering receptor expressed on myeloid cells 2 (TREM2) is emerged as a key immunosuppressive regulator for TAMs, however ...
Qiaohua Wang   +3 more
doaj   +1 more source

LTβR controls thymic portal endothelial cells for haematopoietic progenitor cell homing and T-cell regeneration

open access: yesNature Communications, 2016
Lymphoid progenitors migrate from the bone marrow into the thymus to give rise to T and NK cell lineages. Here the authors characterize a lymphotoxin receptor beta-dependent population of thymic endothelial cells that guide lymphoid progenitor homing in ...
Yaoyao Shi   +13 more
doaj   +1 more source

TICAL - a web-tool for multivariate image clustering and data topology preserving visualization [PDF]

open access: yes, 2011
In life science research bioimaging is often used to study two kinds of features in a sample simultaneously: morphology and co-location of molecular components.
Abouna, Sylvie   +5 more
core  

Cysticercosis and taeniasis cases diagnosed at two referral medical institutions, Belgium, 1990 to 2015 [PDF]

open access: yes, 2019
Background: Few case reports on human infections with the beef tapeworm Taenia saginata and the pork tapeworm, Taenia solium, diagnosed in Belgium have been published, yet the grey literature suggests a higher number of cases.
Bottieau, Emmanuel   +6 more
core   +1 more source

Disulfiram-loaded nanovesicles hydrogel promotes healing of diabetic wound

open access: yesJournal of Translational Medicine
Background Traditional methods for treating diabetic wounds are limited in effectiveness because of their long healing times, the risk of immune rejection, and susceptibility to infection. Suppressing neutrophil extracellular traps (NETs) is an effective
Xingzi Sun   +4 more
doaj   +1 more source

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