Results 11 to 20 of about 4,185,931 (303)

Highlights of the Latest Developments in Radiopharmaceuticals for Infection Imaging and Future Perspectives [PDF]

Frontiers in Medicine, 2022
COVID-19 pandemic has heightened the interest toward diagnosis and treatment of infectious diseases. Nuclear medicine with its powerful scintigraphic, single photon emission computer tomography (SPECT) and positron emission tomography (PET) imaging ...
Ekaterina Dadachova, Drauzio E. N. Rangel   +1 more
doaj   +2 more sources

Radiosynthesis, quality control, biodistribution, and infection-imaging study of a new 99mTc-labeled ertapenem radiopharmaceutical [PDF]

Frontiers in Chemistry, 2022
Ertapenem is a member of carbapenem antibiotics used for the treatment of moderate-to-severe intra-abdominal, urinary tract, acute pelvic, and post-surgical gynecologic infections.
Syed Ali Raza Naqvi, Tania Jabbar, Maha A. Alharbi, Asma Noureen, Nada K. Alharbi, Tauqir A. Sherazi, Anum Shahzadi, Ahmed Ezzat Ahmed, Ahmed Ezzat Ahmed, M. Shahzad Afzal, M. Babar Imran   +10 more
doaj   +2 more sources

Synthesis and Evaluation of Novel Norfloxacin Isonitrile ^99mTc Complexes as Potential Bacterial Infection Imaging Agents [PDF]

Pharmaceutics, 2021
To develop potential technetium-99m single-photon emission computed tomography (SPECT) imaging agents for bacterial infection imaging, the novel norfloxacin isonitrile derivatives CN4NF and CN5NF were synthesized and radiolabeled with a [99mTc][Tc(I ...
Si’an Fang, Yuhao Jiang, Di Xiao, Xuran Zhang, Qianqian Gan, Qing Ruan, Junbo Zhang   +6 more
doaj   +2 more sources

Design, Preparation, and Evaluation of a Novel ^99mTcN Complex of Ciprofloxacin Xanthate as a Potential Bacterial Infection Imaging Agent [PDF]

Molecules, 2020
In order to seek novel technetium-99m bacterial infection imaging agents, a ciprofloxacin xanthate (CPF2XT) was synthesized and radiolabeled with [99mTcN]2+ core to obtain the 99mTcN-CPF2XT complex, which exhibited high radiochemical purity ...
Si’an Fang, Yuhao Jiang, Qianqian Gan, Qing Ruan, Di Xiao, Junbo Zhang   +5 more
doaj   +2 more sources

First-in-human infection imaging with 89Zr-labelled leukocytes and comparison of scan quality with [99mTc]Tc-HMPAO-labelled leukocytes [PDF]

Frontiers in Nuclear Medicine
IntroductionNuclear medicine infection imaging is routinely performed with the use of leukocytes radiolabelled with technetium-99m hexamethylpropyleneamine oxime ([99mTc]Tc-HMPAO) and single-photon emission computed tomography (SPECT).
Maryke Kahts, Beverley Summers, Akhona Nkokheli Ndlela, Aadil Gutta, Aadil Gutta, Phumudzo Nemutaduni, Andrew More, Aman Parsoo, Thomas Ebenhan, Thomas Ebenhan, Jan Rijn Zeevaart, Jan Rijn Zeevaart, Jan Rijn Zeevaart, Omer Aras, Omer Aras, Mike Machaba Sathekge   +15 more
doaj   +2 more sources

Metabolic Imaging of Infection [PDF]

Journal of Nuclear Medicine, 2017
Metabolic imaging has come to occupy a prominent place in the diagnosis and management of microbial infection. Molecular probes available for infection imaging have undergone a rapid evolution starting with nonspecific agents that accumulate similarly in infection, sterile inflammation, and neoplastic tissue and then extending to more targeted probes ...
Lawal, Ismaheel, Zeevaart, JanRijn, Ebenhan, Thomas, Ankrah, Alfred, Vorster, Mariza, Kruger, Hendrik G., Govender, Thavendran, Sathekge, Mike   +7 more
openaire   +5 more sources

Alternative Nuclear Imaging Tools for Infection Imaging. [PDF]

Curr Cardiol Rep, 2022
PURPOSE OF REVIEW: Cardiovascular infections are serious disease associated with high morbidity and mortality. Their diagnosis is challenging, requiring a proper management for a prompt recognition of the clinical manifestations, and a multidisciplinary ...
Erba PA, Bartoli F, Sollini M, Raffaella B, Zanca R, Enrica E, Lazzeri E.   +6 more
europepmc   +3 more sources

Radiotracers for Bone Marrow Infection Imaging. [PDF]

Molecules, 2021
INTRODUCTION: Radiotracers are widely used in medical imaging, using techniques of gamma-camera imaging (scintigraphy and SPECT) or positron emission tomography (PET).
Jødal L, Afzelius P, Alstrup AKO, Jensen SB.   +3 more
europepmc   +2 more sources

Soft X-ray Tomography Reveals HSV-1-Induced Remodeling of Human B Cells

Viruses, 2022
Upon infection, viruses hijack the cell machinery and remodel host cell structures to utilize them for viral proliferation. Since viruses are about a thousand times smaller than their host cells, imaging virus-host interactions at high spatial resolution
Jian-Hua Chen, Bieke Vanslembrouck, Axel Ekman, Vesa Aho, Carolyn A. Larabell, Mark A. Le Gros, Maija Vihinen-Ranta, Venera Weinhardt   +7 more
doaj   +1 more source

In Vitro and In Vivo Evaluation of ^99mTc-Polymyxin B for Specific Targeting of Gram-Bacteria

Biomolecules, 2021
Background: Infectious diseases are one of the main causes of morbidity and mortality worldwide. Nuclear molecular imaging would be of great help to non-invasively discriminate between septic and sterile inflammation through available ...
Sveva Auletta, Filippo Galli, Michela Varani, Giuseppe Campagna, Martina Conserva, Daniela Martinelli, Iolanda Santino, Alberto Signore   +7 more
doaj   +1 more source