Highlights of the Latest Developments in Radiopharmaceuticals for Infection Imaging and Future Perspectives [PDF]
Frontiers in Medicine, 2022 COVID-19 pandemic has heightened the interest toward diagnosis and treatment of infectious diseases. Nuclear medicine with its powerful scintigraphic, single photon emission computer tomography (SPECT) and positron emission tomography (PET) imaging ...
Ekaterina Dadachova +1 more
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Radiosynthesis, quality control, biodistribution, and infection-imaging study of a new 99mTc-labeled ertapenem radiopharmaceutical [PDF]
Frontiers in Chemistry, 2022 Ertapenem is a member of carbapenem antibiotics used for the treatment of moderate-to-severe intra-abdominal, urinary tract, acute pelvic, and post-surgical gynecologic infections.
Syed Ali Raza Naqvi +10 more
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Imaging infection and inflammation [PDF]
BioMed Research International, 2015 No abstract ...
A. W., Glaudemans +3 more
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Synthesis and Evaluation of Novel Norfloxacin Isonitrile 99mTc Complexes as Potential Bacterial Infection Imaging Agents [PDF]
Pharmaceutics, 2021 To develop potential technetium-99m single-photon emission computed tomography (SPECT) imaging agents for bacterial infection imaging, the novel norfloxacin isonitrile derivatives CN4NF and CN5NF were synthesized and radiolabeled with a [99mTc][Tc(I ...
Si’an Fang +6 more
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Design, Preparation, and Evaluation of a Novel 99mTcN Complex of Ciprofloxacin Xanthate as a Potential Bacterial Infection Imaging Agent [PDF]
Molecules, 2020 In order to seek novel technetium-99m bacterial infection imaging agents, a ciprofloxacin xanthate (CPF2XT) was synthesized and radiolabeled with [99mTcN]2+ core to obtain the 99mTcN-CPF2XT complex, which exhibited high radiochemical purity ...
Si’an Fang +5 more
doaj +2 more sources
Alternative Nuclear Imaging Tools for Infection Imaging. [PDF]
Curr Cardiol Rep, 2022 Abstract Purpose of Review Cardiovascular infections are serious disease associated with high morbidity and mortality. Their diagnosis is challenging, requiring a proper management for a prompt recognition of the clinical manifestations, and a multidisciplinary approach involving cardiologists, cardiothoracic surgeons ...
Erba PA +6 more
europepmc +4 more sources
First-in-human infection imaging with 89Zr-labelled leukocytes and comparison of scan quality with [99mTc]Tc-HMPAO-labelled leukocytes [PDF]
Frontiers in Nuclear MedicineIntroductionNuclear medicine infection imaging is routinely performed with the use of leukocytes radiolabelled with technetium-99m hexamethylpropyleneamine oxime ([99mTc]Tc-HMPAO) and single-photon emission computed tomography (SPECT).
Maryke Kahts +15 more
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Soft X-ray Tomography Reveals HSV-1-Induced Remodeling of Human B Cells
Viruses, 2022 Upon infection, viruses hijack the cell machinery and remodel host cell structures to utilize them for viral proliferation. Since viruses are about a thousand times smaller than their host cells, imaging virus-host interactions at high spatial resolution
Jian-Hua Chen +7 more
doaj +1 more source
In Vitro and In Vivo Evaluation of 99mTc-Polymyxin B for Specific Targeting of Gram-Bacteria
Biomolecules, 2021 Background: Infectious diseases are one of the main causes of morbidity and mortality worldwide. Nuclear molecular imaging would be of great help to non-invasively discriminate between septic and sterile inflammation through available ...
Sveva Auletta +7 more
doaj +1 more source
World Journal of Nuclear Medicine, 2021 Synthetic antimicrobial peptide fragment, 99mTc-Ubiquicidin 29–41, is shown to be sensitive and also specific for imaging bacterial infections. We undertook this study to explore the advantage of using a positron emission agent, 68Ga-DOTA-Ubiquicidin 29 ...
Dilip Kumar Boddeti, Vijay Kumar
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