Results 11 to 20 of about 48,541 (237)

RADIOPHARMACEUTICALS

Nature Biotechnology
Radiopharmaceuticals (RPs) have revolutionized the fields of nuclear medicine, diagnostic imaging, and targeted therapy. The chapter begins by elucidating the brief explanation of production and design of RPs. This chapter focuses on newly produced diagnostic & therapeutic radiopharmaceuticals that are being employed in normal clinical settings as ...
Vipasha Sharma, Suman Khurana, Mukesh Rani, Arun Mittal, Parveen Kumar Goyal   +4 more
europepmc   +8 more sources

Influence of Peptide-Based Chelator Sequences on HER2-Targeting Radiopeptide. [PDF]

J Pept Sci
Peptide‐based chelator consisting of Cys‐Gly‐Gly‐Gly incorporated into HER2‐targeting rL‐A9 peptide for 99mTc‐labeling. [99mTc]Tc‐CGGG‐rL‐A9 exhibited high binding affinity and tumor uptake and retention. ABSTRACT In our pursuit of developing HER2‐targeting radiolabeled peptides for detection and therapy of HER2‐positive breast cancer, the previously ...
Gupta S, Kumar M, Repaka KM, Das A, Kengar AA, Satpati D.   +5 more
europepmc   +2 more sources

Future Prospective of Radiopharmaceuticals from Natural Compounds Using Iodine Radioisotopes as Theranostic Agents

Molecules, 2022
Natural compounds provide precursors with various pharmacological activities and play an important role in discovering new chemical entities, including radiopharmaceuticals.
Wiwit Nurhidayah, Luthfi Utami Setyawati, Isti Daruwati, Amirah Mohd Gazzali, Toto Subroto, Muchtaridi Muchtaridi   +5 more
doaj   +1 more source

Influence of Storage Temperature on Radiochemical Purity of 99mTc-Radiopharmaceuticals [PDF]

, 2018
The influence of effective room temperature on the radiochemical purity of 99mTc-radiopharmaceuticals was reported. This study was born from the observation that in the isolators used for the preparation of the 99mTc-radiopharmaceuticals the ...
Bartolomei, Mirco, Boschi, Alessandra, Cittanti, Corrado, Donatella, Farina, Doretta, Bortolotti, Elena, Govoni, Elisa, Zappaterra, Giganti, Melchiore, Luca, Lodi, Martini, Petra, Rizzo, Carlotta, Samanta, Zaccaria, Simona, Romani, Stefania, Bertelli, Uccelli, Licia   +14 more
core   +2 more sources

Nuclear medicine procedures and the evaluation of male sexual organs: a short review [PDF]

, 2008
Sexuality consists of three aspects that are interrelated and inseparable, biological, physiological and social. The biological aspect considers the individual's capability to give and to receive pleasure.
Adenilson de Souza da Fonseca, Bernardo-Filho M., Beutel M. E., Bouchelouche K., Chaffanjon P. C., Choe W., Dennerstein L., Fanti S., Ganjoo K. N., Gerber G., Halac M., Hatzimouratidis H., Jana S., Kevin Carter, Kim C. K., Kolodny R. C., Kotzerke J., Kotzerke J., Kumar V., Lange P. H., Mario Bernardo-Filho, Masters W. H., Orhan I., Perkins A., Perkins A., Ravizzini G., Roivainen A., Ryu J., Saha G., Sebastião David Santos-Filho, Shen Y. Y., Sotiris Missailidis, Stelzner F., Sumich A. L., Timmermans L., Tóth G., Valdés Olmos R. A., Warren G. P., Willan B. D., Zuckier L. S.   +39 more
core   +4 more sources

Development Strategy for Innovation System of Radiopharmaceuticals in China

中国工程科学, 2022
Nuclear medicine plays an irreplaceable role in the diagnosis, therapy, and prognosis of various diseases. Radiopharmaceuticals are the cornerstone of nuclear medicine; their systematic development could accelerate the innovation and clinical application
Peng Shuming, Yang Yuchuan, Yang Xia, Qian Dazhi, Zheng Gangyang, Zhao Xiangeng   +5 more
doaj   +1 more source

Targeted radiotherapy of neuroblastoma: future directions [PDF]

, 2017
No abstract ...
Gaze, Mark N., Mairs, Robert, Nile, Donna L., Rae, Colin, Tesson, Mathias   +4 more
core   +2 more sources

Effect of an extract of Centella asiatica on the biodistribution of sodium pertechnetate (Na^99mTcO₄) and on the fixation of radioactivity on blood constituents [PDF]

, 2008
This study evaluates the effects of an acute treatment with a Centella asiatica (CA) extract on the biodistribution of the radiopharmaceutical Na99mTcO4 and on the fixation of technetium-99m on blood constituents. Wistar rats were treated with CA extract
Adenilson de Souza da Fonseca, Benarroz M. O., Bernardo-Filho M., Capriles P. V., Claudia Leite Diniz, Danielle Santos de Almeida, Fernanda Santos do Carmo, Fonseca A. S., Frydman J. N. G., Goel H. C., Inamdar P. K., Jayashree G., Mario Bernardo Filho, Moreno S.R., Owunwanne A., Padma P. R., Rebello B. M., Saha G. B., Sebastião David Santos-Filho, Sharma J., Shobi V., Simões C. M. O., Sotiris Missailidis   +22 more
core   +4 more sources

Radiopharmaceutical Therapy [PDF]

Health Physics, 2019
Abstract Radiopharmaceutical therapy involves the use of radionuclides that are either conjugated to tumor-targeting agents (e.g., nanoscale constructs, antibodies, peptides, and small molecules) or that concentrate in tumors through natural physiological mechanisms that occur predominantly in neoplastic cells.
openaire   +2 more sources

Evaluation of a PACAP Peptide Analogue Labeled with (68)Ga Using Two Different Chelating Agents. [PDF]

, 2016
OBJECTIVE: The authors have conjugated chelating agents (DOTA and NODAGA) with a peptide (pituitary adenylate cyclase-activating peptide [PACAP] analogue) that has a high affinity for VPAC1 receptors expressed on cancer cells.
Chen, Chang-Po, Kumar, Pardeep, Mehta, Neil, Paudyal, Bishnuhari, Thakur, Mathew L., Tripathi, Sushil Kumar, Wickstrom, Eric   +6 more
core   +2 more sources