Results 31 to 40 of about 38,224 (238)

Innovative radiopharmaceuticals in oncology and neurology [PDF]

, 2017
The aim of this Research Topic was to assemble a series of articles describing basic, preclinical and clinical research studies on radiopharmaceuticals and nuclear medicine.
Michel Cherel, Jacques Barbet, Francoise Kraeber-Bodere, Barbet, Jacques, Kraeber-Bodéré, Françoise, Guilloteau, Denis, Chérel, Michel, Bodere, Francoise Kraeber, Denis Guilloteau   +8 more
core   +1 more source

Clinical translation of theranostic radiopharmaceuticals: Current regulatory status and recent examples [PDF]

, 2019
With the development of ever more radiopharmaceuticals suitable for theranostic applications, translation of novel compounds from the preclinical stage towards clinical application becomes a bottleneck for the advances in Nuclear Medicine.
Rangger C., Mikolajczak R., Clemens Decristoforo, Hubalewska-Dydejczyk A., Decristoforo, Clemens, Maina T., Christine Rangger, Piotr Garnuszek, Garnuszek, Piotr, Erba, Paola, Decristoforo C., Kolenc Peitl, Petra, Hubalewska-Dydejczyk, Alicja, Petra Kolenc Peitl, Theodosia Maina, Mikołajczak, Renata, Maina, Theodosia, Renata Mikolajczak, Paola Erba, Rangger, Christine, Erba P., Garnuszek P., Kolenc Peitl P., Alicja Hubalewska‐Dydejczyk   +23 more
core   +1 more source

Ginsenoside Rb1 can ameliorate the key inflammatory cytokines TNF-α and IL-6 in a cancer cachexia mouse model

BMC Complementary Medicine and Therapies, 2020
Background Cancer cachexia is a severe condition that leads to the death of advanced cancer patients, and approximately 50~80% of cancer patients have cancer cachexia.
Shuai Lu, Yubo Zhang, Huajun Li, Jing Zhang, Yingqian Ci, Mei Han   +5 more
doaj   +1 more source

Methodological Approaches to Preclinical Evaluation of General Toxicity of Therapeutic Radiopharmaceuticals

Регуляторные исследования и экспертиза лекарственных средств, 2021
Radiopharmaceuticals differ from other medicines mainly by the specific nature of their pharmacological action based on radioactivity, by absence of multiple-dose regimens, and by miniscule concentrations of the active pharmaceutical ingredient (10-9–10 ...
O. E. Klementyeva, A. S. Lunev, C. A. Lunyova   +2 more
doaj   +1 more source

Recent Applications of Ambient Ionization Mass Spectrometry for Environmental Pollutant Detection [PDF]

Zhipu Xuebao, 2023
Along with the industrial development and human society progress, large number of pollutants have been discharged to induce the environmental pollution, which have attracted global attentions.
QIN Jing-yi, OUYANG Jin, NA Na
doaj   +1 more source

Pharmacovigilance in radiopharmaceuticals

Indian Journal of Nuclear Medicine, 2016
Indian Pharmacopoeia Commission is Committed for maintaining the standards of drugs including Radiopharmaceuticals (RPs) by publishing Indian Pharmacopoeia. These RPs are being used in India for diagnostic or therapeutic purpose. RPs though contain relatively small quantities of active ingredient and administered in small volumes could cause some ...
Kumar, Rishi, Kalaiselvan, Vivekanandan, Kumar, Rakesh, Verma, Ravendra, Singh, Gyanendra Nath   +4 more
openaire   +3 more sources

Nuclear medicine as a tool for diagnosis and targeted cancer therapy

Бюллетень сибирской медицины, 2018
The main trends and prospects of development of nuclear medicine, problems and possible ways of their solution are considered in the article. The main scientific directions in the development of radiopharmaceuticals for the diagnosis and radionuclide ...
V. I. Chernov, A. A. Medvedeva, I. G. Sinilkin, R. V. Zelchan, O. D. Bragina, E. L. Choynzonov   +5 more
doaj   +1 more source

Synthesis and Evaluation of ^99mTc-Labelled 2-Nitroimidazole Derivatives with Different Linkers for Tumour Hypoxia Imaging

Pharmaceuticals, 2023
When developing novel radiopharmaceuticals, a linker moiety between the chelator and targeting vector can have a crucial influence on adjusting the affinity of the tracer and its biodistribution in organisms.
Qing Ruan, Yitong Liu, Lihao Liao, Jinyu Hao, Yuhao Jiang, Jianyong Jiang, Junbo Zhang   +6 more
doaj   +1 more source

Radiopharmaceutical Therapy [PDF]

Health Physics, 2019
Abstract Radiopharmaceutical therapy involves the use of radionuclides that are either conjugated to tumor-targeting agents (e.g., nanoscale constructs, antibodies, peptides, and small molecules) or that concentrate in tumors through natural physiological mechanisms that occur predominantly in neoplastic cells.
openaire   +2 more sources

Research Progress of Metal-Based Radiopharmaceuticals Targeting Somatostatin Receptor

He huaxue yu fangshe huaxue, 2023
Neuroendocrine tumors(NETs) are a group of heterogeneous tumors originating from neuroendocrine cells. They can occur anywhere in the body, most commonly in the digestive tract, pancreas, and lungs.
QIN Xiang-yu, SHEN Lang-tao
doaj   +1 more source