Results 51 to 60 of about 38,224 (238)
ABSTRACT Electronic waste has emerged as a major environmental challenge, driven by the massive consumption and a limited lifetime of modern electronic devices, stimulating the development of sustainable electronics. Here, an all‐biomaterial gelatin‐choline‐citric acid ([Ch][CA]) ionogel is developed as an active binder to realize self‐sintered ...
Lin Guo +10 more
wiley +1 more source
Recent radiopharmaceutical research at the AAEC Research Establishment. [PDF]
During the past few years a large part of the radiochemical research carried out at Lucas Heights has been devoted to the synthesis of ligands capable of forming chelate complexes with technetium-99m as part of a search for tumour-localising ...
Wilson, JG, Boyd, RE
core
An Overview of Emerging Trends in Targeted Therapy of Triple-Negative Breast Cancer
Triple-negative breast cancer (TNBC) is a biologically diverse, highly aggressive class of breast cancer defined by the absence of estrogen, progesterone, and HER2 receptors.
Anuj Kumar, Suresh Subramanian
doaj +1 more source
Background Highly sensitive digital total-body PET/CT scanners (uEXPLORER) have great potential for clinical applications and fundamental research. Given their increasing sensitivity, low-dose scanning or snapshot imaging is now possible in clinics ...
Yanchao Huang +10 more
doaj +1 more source
Conjugated poly(imide dioxime)‐based microspheres establish a radiometal coordination‐driven conformational interlocked network with ultra‐high radiostability. This platform enables low‐temperature, multi‐radionuclide labeling for SPECT/PET/MRI imaging and radionuclide therapy. Mechanistic insights from EXAFS and DFT reveal enhanced stability, while in
Xiao Xu +10 more
wiley +1 more source
Toward Personalized Theranostics: A Modular PET Platform for Antibody‐Based Imaging and Therapy
This modular, site‐specific antibody platform enables customizable conjugates for PET imaging and therapy. Interchangeable payloads – including radiometals, cytotoxics, and fluorophores – support adaptable, multimodal applications with limited off‐target effects. In vivo, the DFO/DOTAGA bischelate immunoconjugate provided clear tumor delineation in PET/
Delphine Vivier +16 more
wiley +1 more source
Síntese, caracterização e avaliação de citotoxicidade de novos ligantes não-simétricos e seus complexos mononucleares, homo e heterobinucleares [PDF]
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Físicas e Matemáticas, Programa de Pós-Graduação em Química, Florianópolis, 2014.Os fármacos utilizados na terapia do câncer apresentam elevados graus de toxicidade ...
Fonseca, Alexandra de Souza
core
Radiopharmaceuticals Used in Molecular Imaging [PDF]
Molecular imaging technology can be used for many applications, including drug development, clinical investigations,and diagnostic techniques. Molecular imaging techniques depend upon molecular mechanisms operating in vivo.
Ekinci, Meliha +2 more
core +1 more source
Glutathione (GSH)‐activated prodrugs are promising for overcoming the limitations of conventional anti‐tumor drugs. However, current GSH‐responsive disulfide groups exhibit unregulated reactivity, making it impossible to precisely control the drug ...
Si‐Yu Wang +6 more
doaj +1 more source
Application of chiral 2-isoxazoline for the synthesis of syn-1,3-diol analogs
The asymmetric cycloaddition of TIPS nitronate catalyzed by “Cu(II)-bisoxazoline” gave the 2-isoxazoline product in 95% yield, which was converted into tert-butyl (3S,5R)-6-hydroxy-3,5-O-isopropylidene-3,5-dihydroxyhexanoate in 14 steps through a β ...
Juanjuan Feng +3 more
doaj +1 more source

