Results 21 to 30 of about 28,331 (208)

Radiolabeling and Biological Evaluation of Novel ^99mTc-Nitrido and ^99mTc-Oxo Complexes with 4-Methoxy-_L-Phenylalanine Dithiocarbamate for Tumor Imaging

Pharmaceutics, 2022
To develop novel radiolabeled amino acid tumor imaging agents, 4-methoxy-L-phenylalanine dithiocarbamate (MOPADTC) was synthesized successfully, and two kinds of 99mTc-labeled complexes ([99mTc]TcN-MOPADTC and [99mTc]TcO-MOPADTC) with high radiochemical ...
Guangxing Yin, Qing Ruan, Yuhao Jiang, Junbo Zhang   +3 more
doaj   +1 more source

Future Prospective of Radiopharmaceuticals from Natural Compounds Using Iodine Radioisotopes as Theranostic Agents

Molecules, 2022
Natural compounds provide precursors with various pharmacological activities and play an important role in discovering new chemical entities, including radiopharmaceuticals.
Wiwit Nurhidayah, Luthfi Utami Setyawati, Isti Daruwati, Amirah Mohd Gazzali, Toto Subroto, Muchtaridi Muchtaridi   +5 more
doaj   +1 more source

Synthesis and Evaluation of Novel Norfloxacin Isonitrile ^99mTc Complexes as Potential Bacterial Infection Imaging Agents

Pharmaceutics, 2021
To develop potential technetium-99m single-photon emission computed tomography (SPECT) imaging agents for bacterial infection imaging, the novel norfloxacin isonitrile derivatives CN4NF and CN5NF were synthesized and radiolabeled with a [99mTc][Tc(I ...
Si’an Fang, Yuhao Jiang, Di Xiao, Xuran Zhang, Qianqian Gan, Qing Ruan, Junbo Zhang   +6 more
doaj   +1 more source

Development Strategy for Innovation System of Radiopharmaceuticals in China

中国工程科学, 2022
Nuclear medicine plays an irreplaceable role in the diagnosis, therapy, and prognosis of various diseases. Radiopharmaceuticals are the cornerstone of nuclear medicine; their systematic development could accelerate the innovation and clinical application
Peng Shuming, Yang Yuchuan, Yang Xia, Qian Dazhi, Zheng Gangyang, Zhao Xiangeng   +5 more
doaj   +1 more source

Methodological Approaches to Preclinical Evaluation of General Toxicity of Therapeutic Radiopharmaceuticals

Регуляторные исследования и экспертиза лекарственных средств, 2021
Radiopharmaceuticals differ from other medicines mainly by the specific nature of their pharmacological action based on radioactivity, by absence of multiple-dose regimens, and by miniscule concentrations of the active pharmaceutical ingredient (10-9–10 ...
O. E. Klementyeva, A. S. Lunev, C. A. Lunyova   +2 more
doaj   +1 more source

Ginsenoside Rb1 can ameliorate the key inflammatory cytokines TNF-α and IL-6 in a cancer cachexia mouse model

BMC Complementary Medicine and Therapies, 2020
Background Cancer cachexia is a severe condition that leads to the death of advanced cancer patients, and approximately 50~80% of cancer patients have cancer cachexia.
Shuai Lu, Yubo Zhang, Huajun Li, Jing Zhang, Yingqian Ci, Mei Han   +5 more
doaj   +1 more source

Recent Applications of Ambient Ionization Mass Spectrometry for Environmental Pollutant Detection [PDF]

Zhipu Xuebao, 2023
Along with the industrial development and human society progress, large number of pollutants have been discharged to induce the environmental pollution, which have attracted global attentions.
QIN Jing-yi, OUYANG Jin, NA Na
doaj   +1 more source

Radiopharmaceuticals in cardiology

Nuclear Medicine Review, 2012
Myocardial perfusion studies are among the most often performed investigations in Nuclear Medicine. However, the development of radiopharmaceuticals for cardiology is an emerging discipline and several other radiotracers have been proven to be useful.
Renata, Mikołajczak, Piotr, Garnuszek
openaire   +3 more sources

Pharmacovigilance in radiopharmaceuticals

Indian Journal of Nuclear Medicine, 2016
Indian Pharmacopoeia Commission is Committed for maintaining the standards of drugs including Radiopharmaceuticals (RPs) by publishing Indian Pharmacopoeia. These RPs are being used in India for diagnostic or therapeutic purpose. RPs though contain relatively small quantities of active ingredient and administered in small volumes could cause some ...
Kumar, Rishi, Kalaiselvan, Vivekanandan, Kumar, Rakesh, Verma, Ravendra, Singh, Gyanendra Nath   +4 more
openaire   +3 more sources

Nuclear medicine as a tool for diagnosis and targeted cancer therapy

Бюллетень сибирской медицины, 2018
The main trends and prospects of development of nuclear medicine, problems and possible ways of their solution are considered in the article. The main scientific directions in the development of radiopharmaceuticals for the diagnosis and radionuclide ...
V. I. Chernov, A. A. Medvedeva, I. G. Sinilkin, R. V. Zelchan, O. D. Bragina, E. L. Choynzonov   +5 more
doaj   +1 more source