Results 21 to 30 of about 38,224 (238)

Preparation and Bioevaluation of a Novel ^99mTc-Labeled Glucose Derivative Containing Cyclohexane as a Promising Tumor Imaging Agent

Pharmaceuticals, 2023
To develop novel tumor imaging agents with high tumor uptake and excellent tumor/non-target ratios, a glucose derivative containing cyclohexane (CNMCHDG) was synthesized and labeled with Tc-99m.
Junhong Feng, Xuran Zhang, Yuhao Jiang, Qing Ruan, Qianna Wang, Junbo Zhang   +5 more
doaj   +1 more source

Adverse reactions to radiopharmaceuticals [PDF]

Farmacia Hospitalaria, 2021
Spanish Royal Legislative Decree 1/2015 of July 24 considered radiopharmaceuticals to be drugs subject to current legislation on this matter. After Radiopharmaceuticals are prepared in Radiopharmacy Departments, they are administered to patients to ...
María del Val Gómez-Martínez, Marta Soler-Vigil, Carla de Gracia-Rodríguez, Purificación Pastor-Fructuoso, Juan Antonio Pérez-Iruela   +4 more
doaj   +1 more source

Hydroxypyridinones as a Very Promising Platform for Targeted Diagnostic and Therapeutic Radiopharmaceuticals

Molecules, 2021
Hydroxypyridinones (HOPOs) have been used in the chelation therapy of iron and actinide metals. Their application in metal-based radiopharmaceuticals has also been increasing in recent years.
Xu Zhou, Linlin Dong, Langtao Shen
doaj   +1 more source

The Radiobiology of Radiopharmaceuticals

Seminars in Radiation Oncology, 2021
Radiopharmaceutical therapy or targeted radionuclide therapy (TRT) is a well-established class of cancer therapeutics that includes a growing number of FDA-approved drugs and a promising pipeline of experimental therapeutics. Radiobiology is fundamental to a mechanistic understanding of the therapeutic capacity of these agents and their potential ...
Zachary S, Morris, Andrew Z, Wang, Susan J, Knox   +2 more
openaire   +3 more sources

Evidence-Based Data About Prevalence and Risk of Malignancy of Thyroid Incidentalomas Detected by Different PET Radiopharmaceuticals.

, 2020
To date, several meta-analyses and systematic reviews have reported data about the prevalence and risk of malignancy of thyroid incidentalomas detected by different PET radiopharmaceuticals.
Albano, D., Giovanella, L., Bertagna, F., Treglia, G., Signore, G.   +4 more
core   +2 more sources

Radiolabeling and Biological Evaluation of Novel ^99mTc-Nitrido and ^99mTc-Oxo Complexes with 4-Methoxy-_L-Phenylalanine Dithiocarbamate for Tumor Imaging

Pharmaceutics, 2022
To develop novel radiolabeled amino acid tumor imaging agents, 4-methoxy-L-phenylalanine dithiocarbamate (MOPADTC) was synthesized successfully, and two kinds of 99mTc-labeled complexes ([99mTc]TcN-MOPADTC and [99mTc]TcO-MOPADTC) with high radiochemical ...
Guangxing Yin, Qing Ruan, Yuhao Jiang, Junbo Zhang   +3 more
doaj   +1 more source

Exploring drug safety of radiopharmaceuticals [PDF]

, 2021
Radioactive substances play an important role in medicine. These so-called radiopharmaceuticals are needed for nuclear scans to diagnose disease and sometimes as a treatment, which uses radiation to kill unwanted cells, such as cancer cells, in the body ...
Schreuder, Nanno
core   +3 more sources

Radiopharmaceuticals

, 2022
Radiopharmaceuticals - Current Research for Better Diagnosis and Therapy discusses the importance of radiopharmaceuticals and their environmental, pharmaceutical, diagnostic, therapeutic, and research applications.

core   +1 more source

Synthesis and Evaluation of Novel Norfloxacin Isonitrile ^99mTc Complexes as Potential Bacterial Infection Imaging Agents

Pharmaceutics, 2021
To develop potential technetium-99m single-photon emission computed tomography (SPECT) imaging agents for bacterial infection imaging, the novel norfloxacin isonitrile derivatives CN4NF and CN5NF were synthesized and radiolabeled with a [99mTc][Tc(I ...
Si’an Fang, Yuhao Jiang, Di Xiao, Xuran Zhang, Qianqian Gan, Qing Ruan, Junbo Zhang   +6 more
doaj   +1 more source

Future Prospective of Radiopharmaceuticals from Natural Compounds Using Iodine Radioisotopes as Theranostic Agents

Molecules, 2022
Natural compounds provide precursors with various pharmacological activities and play an important role in discovering new chemical entities, including radiopharmaceuticals.
Wiwit Nurhidayah, Luthfi Utami Setyawati, Isti Daruwati, Amirah Mohd Gazzali, Toto Subroto, Muchtaridi Muchtaridi   +5 more
doaj   +1 more source