Results 61 to 70 of about 5,812,051 (309)

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Comparative Inventory Assessment of Greenhouse Gas Mitigation Technologies in the Cropland Sector and Policy Implications for Korea [PDF]

대한환경공학회지
In response to the increasing urgency of climate change mitigation and the pursuit of carbon neutrality, the role of greenhouse gas (GHG) reduction in the agricultural sector has garnered significant attention.
Su-Heon Jang, Taeyoung Kim, Seong-Jik Park   +2 more
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

Fatores de emissão de compostos carbonílicos medidos em um túnel do Rio de Janeiro, Brasil, em condições reais de dirigibilidade

Química Nova
Real-world vehicle emissions of carbonyls compounds (CC) were determined at the Rebouças Tunnel, Rio de Janeiro (Brazil). The tunnel is a two-bore tunnel with three lanes in each direction and has a length of 2840 m, divided in two sections.
Jose Claudino Souza Almeida, Andre Luis do Prado Braga, Leonardo Bastos, Graciela Arbilla, Eduardo Monteiro Martins   +4 more
doaj   +1 more source

Transient Characterization of Automotive Exhaust Emission from Different Vehicle Types Based on On-Road Measurements

Atmosphere, 2020
Previous works on real-world vehicle emission characteristics have mainly focused on the influences of fuel, speed, vehicle type, elevation, and other factors on vehicle emission quantity and components.
Chao Ma, Lin Wu, Hong-jun Mao, Xiao-zhen Fang, Ning Wei, Jin-sheng Zhang, Zhi-wen Yang, Yan-jie Zhang, Zong-yan Lv, Lei Yang   +9 more
doaj   +1 more source

Temporal variation in nitrous oxide (N2O) fluxes from an oil palm plantation in Indonesia: An ecosystem‐scale analysis

GCB Bioenergy, 2023
The rapidly growing areal extent of oil palm (Elaeis guineensis Jacq.) plantations and their high fertilizer input raises concerns about their role as substantial N2O sources.
Christian Stiegler, Franziska Koebsch, Ashehad Ashween Ali, Tania June, Edzo Veldkamp, Marife D. Corre, Joost Koks, Aiyen Tjoa, Alexander Knohl   +8 more
doaj   +1 more source

Environmental/economic dispatch considering emission benefit factor in the emission trading environment

, 2011
PurposeThe efficiency of the emission trading system (ETS) may help to control the total emission amount. The purpose of this paper is to investigate the generating cost issue in environmental/economic power dispatch, under the premise that the ETS has ...
Fushuan Wen, Zhongbin Bai, Bai, Zhongbin, Wen, Fushuan, Wen, Buying, Buying Wen   +5 more
core   +1 more source

Carbon dioxide emission factor estimation from Indonesian coal [PDF]

, 2018
Climate change will become the priority for the air quality management. It focuses more on carbon dioxide emission. Indonesia which has power generation dominated by coal combustion is expected to develop the national CO2 emission factor. Due to the high
Khaerunissa, Herni, Damayanti, Retno, Retno Damayanti, Herni Khaerunissa   +3 more
core   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source