Results 71 to 80 of about 344,061 (314)
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Observation of O+ 4P-4D0 lines in proton aurora over Svalbard [PDF]
, 2004 Spectra of a proton aurora event show lines of O+ 4P-4D0 multiplet (4639–4696 Å) enhanced relative to the N2 +1N(0,2) compared to normal electron aurora. Conjugate satellite particle measurements are used as input to electron and proton transport models,
Ivchenko, N. +6 more
core
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Emission Lines from Companion Galaxies of QSOs [PDF]
, 2007 Anticipating new spectroscopic studies of quasar companions, we calculate expected emission line spectra for the companion galaxies. Under the assumption of isotropic photoionizing radiation, we predict equivalent widths for Hff, Hfi, [O iii] 5007, [O ii]
Oleg Gnedin
core
Optical Emission Lines and the X-Ray Properties of Type 1 Seyfert Galaxies
Open Astronomy, 2011 In this contribution we report on the study of the optical emission lines and X-ray spectra of a sample of Type 1 AGNs, collected from the SDSS database and observed by the XMM-Newton satellite.
La Mura G. +5 more
doaj +1 more source
The Astrophysical Journal, 2023 Differential emission measure (DEM) inversion methods use the brightness of a set of emission lines to infer the line-of-sight (LOS) distribution of the electron temperature ( T _e ) in the corona.
Benjamin Boe +2 more
doaj +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Spectral optical monitoring of a double-peaked emission line AGN Arp 102B: Variability of spectral lines and continuum⋆ [PDF]
, 2013 Context. We present results of long-term (1987–2010) optical spectral monitoring of the broad-line radio galaxy Arp 102B, a prototype of an active galactic nucleus with double-peaked broad emission lines that are commonly assumed to be emitted from an ...
Luis Carrasco Bazúa +4 more
core
Hydrogen effects on copper, zinc and nickel atomic emission lines in argon radiofrequency glow discharge optical emission spectrometry [PDF]
, 2008 The effect of hydrogen (0.5%, 1% and 10% v/v) added to the argon plasma gas on the emission spectra of selected atomic lines for copper, zinc and nickel has been studied by radiofrequency glow discharge optical emission spectrometry (rf-GD-OES ...
Bordel García, Nerea +3 more
core +1 more source
A study of line shape of CO infrared emission lines
Journal of Research of the National Bureau of Standards Section A: Physics and Chemistry, 1971 The shape of several vibration-rotation lines of CO emitted by a C2H2-O2 flame was investigated. An equivalent width measurement was made using an absorption cell of room temperature CO as an analyzer. Analysis of the data showed that line shapes could be fitted to a Voigt function with shape parameters a between 1.0 and 1.5.
James A, Dowling +3 more
openaire +2 more sources