Results 51 to 60 of about 442,040 (268)

Unveiling consumer satisfaction and its driving factors of EVs in China using an explainable artificial intelligence approach

Humanities & Social Sciences Communications
As China’s electric vehicle (EV) industry shifts from policy-driven to market-oriented development, understanding post-purchase satisfaction and its driving factors becomes imperative.
Chaoxi Liang, Qingtao Yang, Hongyuan Sun, Xiaoming Ma   +3 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Syngas Generation from Methane Using a Chemical-Looping Concept: A Review of Oxygen Carriers

Journal of Chemistry, 2013
Conversion of methane to syngas using a chemical-looping concept is a novel method for syngas generation. This process is based on the transfer of gaseous oxygen source to fuel (e.g., methane) by means of a cycling process using solid oxides as oxygen ...
Kongzhai Li, Hua Wang, Yonggang Wei
doaj   +1 more source

Methane Emission Reduction: An Application of FUND [PDF]

Climatic Change, 2003
Methane is, after carbon dioxide, the most important anthropogenic greenhouse gas. Governments plan to abate methane emissions. A crude set of estimates of reduction costs is included in FUND, an integrated assessment model of climate change. In a cost-benefit analysis, methane emission reduction is found to be instrumental in controlling the optimal ...
Tol, R.S.J., Heintz, R.J., Lammers, P.E.M.   +2 more
openaire   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Enhancing phenological model accuracy in subtropical forests using data assimilation coupled with deep learning

GIScience & Remote Sensing
Accurate monitoring of forest phenology and its temporal and spatial pattern has significant scientific relevance in revealing the carbon fixation mechanism.
Hongyu Zhu, Xuejian Li, Huaqiang Du, Li Chen, Fangjie Mao, Jie Xuan, Yinyin Zhao, Zihao Huang, Kehan Mo, Yuanqing Zheng   +9 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Biochar‐Based Compound Fertilizers Enhances Carbon Sequestration and Mitigates Greenhouse Gas Emissions in Moso Bamboo Forests

GCB Bioenergy
Moso bamboo (Phyllostachys edulis) forests play a significant role in carbon sequestration, but their sustainability is threatened by nutrient depletion and greenhouse gas (GHG) emissions.
Xuekun Cheng, Yufeng Zhou, Guomo Zhou, Yongjun Shi   +3 more
doaj   +1 more source

New Estimation of the Dosage of Scale Inhibitor in the Cooling Water System

E-Journal of Chemistry, 2011
In the cooling water system, excessive use of organic phosphate scale inhibitors is harmful to environment. Reducing the dosage of the organic phosphate scale inhibitor is important. A self-made jacketed crystallizer was used in this experiment.
Jiang Jiaomei, Xu Yanhua
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source