Results 51 to 60 of about 1,347,026 (317)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

New Estimation of the Dosage of Scale Inhibitor in the Cooling Water System

E-Journal of Chemistry, 2011
In the cooling water system, excessive use of organic phosphate scale inhibitors is harmful to environment. Reducing the dosage of the organic phosphate scale inhibitor is important. A self-made jacketed crystallizer was used in this experiment.
Jiang Jiaomei, Xu Yanhua
doaj   +1 more source

Influence of the stop/start system on CO2 emissions of a diesel vehicle in urban traffic [PDF]

, 2011
This paper presents measurements of CO2 emission and efficiency of stop/start technology on a diesel vehicle in urban traffic. Two four-wheel-drive diesel vehicles with on-board exhaust emission and vehicle activity measurement systems were tested in two
Casanova Kindelán, Jesús, Fonseca González, Natalia Elizabeth, Valdés del Fresno, Manuel   +2 more
core   +2 more sources

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Biochar‐Based Compound Fertilizers Enhances Carbon Sequestration and Mitigates Greenhouse Gas Emissions in Moso Bamboo Forests

GCB Bioenergy
Moso bamboo (Phyllostachys edulis) forests play a significant role in carbon sequestration, but their sustainability is threatened by nutrient depletion and greenhouse gas (GHG) emissions.
Xuekun Cheng, Yufeng Zhou, Guomo Zhou, Yongjun Shi   +3 more
doaj   +1 more source

Enhancing phenological model accuracy in subtropical forests using data assimilation coupled with deep learning

GIScience & Remote Sensing
Accurate monitoring of forest phenology and its temporal and spatial pattern has significant scientific relevance in revealing the carbon fixation mechanism.
Hongyu Zhu, Xuejian Li, Huaqiang Du, Li Chen, Fangjie Mao, Jie Xuan, Yinyin Zhao, Zihao Huang, Kehan Mo, Yuanqing Zheng   +9 more
doaj   +1 more source

Exergy Analysis of Flat Plate Solar Collectors

Entropy, 2014
This study proposes the concept of the local heat loss coefficient and examines the calculation method for the average heat loss coefficient and the average absorber plate temperature.
Zhong Ge, Huitao Wang, Hua Wang, Songyuan Zhang, Xin Guan   +4 more
doaj   +1 more source

A High‐Sensitivity Circulating Nucleic Acid Sequencing Assay for Assessing Treatment Response to Alectinib in a Pediatric Patient With ALK‐Rearranged Non–Small Cell Lung Cancer

Pediatric Blood &Cancer, EarlyView.
Alberto D. Guerra, Nicholas F. Evageliou, Vandana Batra, Kristen L. Dalton, Stephanie Ortel, Usman Ashraf, Tricia R. Bhatti, Lisa J. States, Lea F. Surrey, Theodore W. Laetsch   +9 more
wiley   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Candidate Coronagraphic Detections of Protoplanetary Disks around Four Young Stars

, 2009
We present potential detections of H-band scattered light emission around four young star, selected from a total sample of 45 young stars observed with the CIAO coronagraph of the Subaru telescope.
Andrews, Andrews, Beichman, Cieza, Cotera, Cutri, Dutrey, Egan, Fukagawa, Furlan, Hartmann, Heap, Hessman, Hioki, Hodapp, Itoh, Itoh, J. L. Karr, Koresko, Krist, Kudo, Lada, M. Tamura, Mayama, Monet, Murakawa, N. Ohashi, Oppenheimer, Padgett, Padgett, Robitaille, Robitaille, Sicilia-Aguilar, T. Kudo, Whitney, Whitney, Whittet, Wood   +37 more
core   +1 more source