Results 51 to 60 of about 4,494,434 (248)

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Diesel knock combustion and its detection using acoustic emission [PDF]

, 2011
This paper presents an experimental investigation into the detection of excessive Diesel knock using acoustic emission signals. Three different dual-fuel Diesel engine operating regimes were induced into a compression ignition (Diesel) engine operating ...
Lowe, David Patrick, Wu, Weiliang, Tan, Andy C. C., Lin, Tian Ran   +3 more
core  

Biochar‐Based Compound Fertilizers Enhances Carbon Sequestration and Mitigates Greenhouse Gas Emissions in Moso Bamboo Forests

GCB Bioenergy
Moso bamboo (Phyllostachys edulis) forests play a significant role in carbon sequestration, but their sustainability is threatened by nutrient depletion and greenhouse gas (GHG) emissions.
Xuekun Cheng, Yufeng Zhou, Guomo Zhou, Yongjun Shi   +3 more
doaj   +1 more source

Enhancing phenological model accuracy in subtropical forests using data assimilation coupled with deep learning

GIScience & Remote Sensing
Accurate monitoring of forest phenology and its temporal and spatial pattern has significant scientific relevance in revealing the carbon fixation mechanism.
Hongyu Zhu, Xuejian Li, Huaqiang Du, Li Chen, Fangjie Mao, Jie Xuan, Yinyin Zhao, Zihao Huang, Kehan Mo, Yuanqing Zheng   +9 more
doaj   +1 more source

New Estimation of the Dosage of Scale Inhibitor in the Cooling Water System

E-Journal of Chemistry, 2011
In the cooling water system, excessive use of organic phosphate scale inhibitors is harmful to environment. Reducing the dosage of the organic phosphate scale inhibitor is important. A self-made jacketed crystallizer was used in this experiment.
Jiang Jiaomei, Xu Yanhua
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Exergy Analysis of Flat Plate Solar Collectors

Entropy, 2014
This study proposes the concept of the local heat loss coefficient and examines the calculation method for the average heat loss coefficient and the average absorber plate temperature.
Zhong Ge, Huitao Wang, Hua Wang, Songyuan Zhang, Xin Guan   +4 more
doaj   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source