Results 41 to 50 of about 152,383 (315)

Effects of tillage and nitrogen fertilizers on CH4 and CO2 emissions and soil organic carbon in paddy fields of central China.

PLoS ONE, 2012
Quantifying carbon (C) sequestration in paddy soils is necessary to help better understand the effect of agricultural practices on the C cycle. The objective of the present study was to assess the effects of tillage practices [conventional tillage (CT ...
Li Cheng-Fang, Zhou Dan-Na, Kou Zhi-Kui, Zhang Zhi-Sheng, Wang Jin-Ping, Cai Ming-Li, Cao Cou-Gui   +6 more
doaj   +1 more source

Modelling of the continuum emission from Class 0 sources

, 2003
Class 0 sources are objects representing the earliest phase of the protostellar evolution. Since they are highly obscured by an extended dusty envelope, these objects emit mainly in the far-infrared to millimetre wavelength range. The analysis of their spectral energy distributions with wide wavelength coverage allows to determine the bolometric ...
Rengel, M., Froebrich, D., Wolf, S., Eisloeffel, J.   +3 more
openaire   +2 more sources

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Using Otoacoustic emissions as a biometric

, 2004
This paper presents research into using otoacoustic emissions (OAE) as a biometric. OAE are a group of sounds emitted by the cochlea of the ear. The main types are spontaneous OAE which are continuously emitted and the transient and distortion product ...
Matthew A. Swabey, Beeby, S.P., Brown, A.D., Stephen P. Beeby, Chad, J.E., Swabey, M.A., Andrew D. Brown, John E. Chad   +7 more
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Impact of Feeding Level and Multi-Nutrient Blocks with Polyherbals on Weight Changes and Greenhouse Gas Emissions in Lambs

Animals
In small-scale livestock production systems, low-quality diets constrain animal performance and increase enteric emissions, but both these impacts can be remediated using optimized feeding strategies.
Nallely Sánchez-López, Germán David Mendoza-Martínez, María Eugenia de la Torre-Hernández, Pedro Abel Hernández-García, Cesar Díaz-Galván, Gilberto Carlos Ortega-Navarro, Mariela Hada Fuentes Ponce, Abel Jaime Leal-González, Santiago López Ridaura, Jelle Van Loon   +9 more
doaj   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

The Effects of Biochar Incorporation on the CO2, N2O, and CH4 Emissions from the Soils of Stallholder Palm Oil Plantations, Jambi Province Indonesia

Journal of Applied Agricultural Science and Technology, 2023
The domestic agricultural sector contributes 18% to the national greenhouse gas emissions (GHG); which is higher compared to its global counterpart. Biochar incorporation into the soils shows the potential to reduce soil GHG emissions.
Damris Muhammad, Ngatijo Ngatijo, Ira Galih Prabasari, Bunga Mardhotillah   +3 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source