Results 51 to 60 of about 9,547 (300)

Newborn Skin Care is the Basis for Prevention of Atopic Dermatitis Development

Вопросы современной педиатрии, 2021
Healthy newborn skin care is challenging task. The basic principles of care should be taught to both medical staff and parents. This care is more crucial in children with atopic dermatitis who have abnormal skin acidity due to multifactorial exposure ...
Nikolay N. Murashkin, Leonid A. Opryatin, Roman V. Epishev, Alexander I. Materikin, Eduard T. Ambarchyan, Roman A. Ivanov, Dmitriy V. Fedorov, Daria S. Kukoleva   +7 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

An evidence-based guideline on emollient therapy for skin care in premature infants

, 2013
Skin is the major protective barrier in a human body. In premature infants, the immature skin barrier reduces the protection against germs. Emollient therapy is an effective prophylactic measure to improve premature infants’ skin condition so as to ...
Ho, Wing-yan, Vivian, 何穎恩
core   +1 more source

Optimization of Ultrasound-Assisted Emulsification of Emollient Nanoemulsions of Seed Oil of Passiflora edulis var. edulis

, 2020
Passiflora edulis var. edulis is a plant of commercial interest because of it fruits. The seeds, a by-product in the food industry, can be a source of oil for cosmetic, pharmaceutical and food industries.
Maritza Adelina Rojas, Marcela Aragón, Caterine Guzmán   +2 more
core   +1 more source

Perceptions, beliefs, and current practices regarding neonatal skin care and emollient use in eastern Uganda: a qualitative study [PDF]

, 2023
Background The skin is a major route of infection in the neonatal period, especially in low birthweight (LBW) infants. Appropriate and safe neonatal skin care practices are required to reduce this risk.
Peter Waiswa, Kiguli, S, Burgoine, Kathy, Clarke, A, Sarah LA Williams, Gary L Darmstadt, Waiswa, P, Ritah Nantale, Andrew Clarke, Keona JH Blanks, Kathy Burgoine, Nantale, R, Kiguli, Sarah, Darmstadt, Gary L, Blanks, Keona Jh, English, M, Nawanga, Jascenti, Gebremichael, Tewodros, Clarke, Andrew, Daniel Wenani, Waiswa, Peter, Musaba, Milton, Blanks, KJ, Gebremichael, T, Joseph KB Matovu, Sarah Kiguli, Musaba, M, Burgoine, K, Darmstadt, GL, Jascenti Nawanga, Tewodros Gebremichael, Nawanga, J, David Mukunya, Mike English, Wenani, Daniel, Mukunya, David, Mukunya, D, Nantale, Ritah, Williams, SL, Matovu, Joseph Kb, English, Mike, Milton Musaba, Matovu, JKB, Wenani, D, Williams, Sarah LA   +44 more
core   +1 more source

Cost Effectiveness of Emollients in the Prevention of Relapses in Atopic Dermatitis

Clinical, Cosmetic and Investigational Dermatology, 2020
Elise Cabout,1 Sebastien Eymere,1 Robert Launois,1 Flavia Aslanian,2 Charles Taïeb,3,4 Sophie Seité5 1Réseau d’évaluation en Économie de la Santé (REES), Paris, France; 2Epsom and St Helier University ...
Cabout E, Eymere S, Launois R, Aslanian F, Taïeb C, Seité S   +5 more
doaj  

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

Molecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh, Ji Yun Jang, Yoon Jeon, Gi‐Cheon Kim, Hwanho Lee, Jooyoung Lee, Ju‐Hwa Kim, Hakhyun Kim, Minjee Kim, Ho‐Keun Kwon, Ho Lee, Hyun Seok Kim   +11 more
wiley   +1 more source

Heterotropic regulation and negative homotropic cooperativity

FEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea, Francesco Angelucci, Federica Arnesano, Gianmarco Pascarella, Patrizio Di Micco, Andrea Bellelli   +5 more
wiley   +1 more source

Contact allergens in moisturizers in preventative emollient therapy – A systematic review [PDF]

, 2022
BACKGROUND: Results of preventative emollient therapy on atopic dermatitis and food allergy trials are inconsistent. In addition to the ingredients considered beneficial, the moisturizers may contain potentially harmful haptens.
Feleszko, Wojciech, Klaudia Ryczaj, Dumycz, Karolina, Spiewak, Radoslaw, Wojciech Feleszko, Ryczaj, Klaudia, Śpiewak, Radosław, Karolina Dumycz, Radoslaw Spiewak   +8 more
core   +1 more source

Clinical Impact of MGMT Promoter Methylation in IDH‐Mutant Gliomas: Influence of Threshold Selection and Clinical Confounding

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background The clinical relevance of MGMT promoter methylation in IDH‐mutant gliomas remains controversial in the era of molecular classification. We aimed to systematically evaluate its clinical relevance by integrating quantitative assessment, cutoff exploration, and adjustment for clinical confounding.
Haihui Jiang, Linxi Cao, Xiaodong Chen, Siqi Tong, Qinghui Zhu, Jun Yang, Song Lin, Yong Cui   +7 more
wiley   +1 more source