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Feeding the Skin Barrier: The Impact of Macro‐ and Micronutrients on Skin Barrier Function [PDF]
Clinical and Translational AllergyBackground Skin is the largest organ of the human body, and acts as a fundamental barrier. Beyond its protective role, it serves as a key immune organ, mediating immune surveillance and regulation.
Klaudia Ryczaj +2 more
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Dermatology Research and Practice, 2012 The largest organ of the human body is the skin with its ~2 m2 surface area that envelopes the whole organism defining its physical border and which most importantly provides a barrier against internal organ dehydration and external penetration of noxious substances.
Georgios N. Stamatas +3 more
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Anais Brasileiros de Dermatologia, 2016 Recent studies about the cutaneous barrier demonstrated consistent evidence that the stratum corneum is a metabolically active structure and also has adaptive functions, may play a regulatory role in the inflammatory response with activation of ...
Flavia Alvim Sant'Anna Addor
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Cytokines and the Skin Barrier [PDF]
International Journal of Molecular Sciences, 2013 The skin is the largest organ of the human body and builds a barrier to protect us from the harmful environment and also from unregulated loss of water. Keratinocytes form the skin barrier by undergoing a highly complex differentiation process that involves changing their morphology and structural integrity, a process referred to as cornification ...
Christian Cornelissen +2 more
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Skin Barrier Function: The Interplay of Physical, Chemical, and Immunologic Properties
Cells, 2023 An intact barrier function of the skin is important in maintaining skin health. The regulation of the skin barrier depends on a multitude of molecular and immunological signaling pathways.
Paola Baker +5 more
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Diet and Skin Barrier: The Role of Dietary Interventions on Skin Barrier Function
Dermatology Practical & Conceptual, 2021 Multiple research studies have examined the role of specific dietary interventions and their effects on skin barrier function. The skin barrier is one of the body's first lines of protection against environmental insults, and disruption of this natural ...
Milbrey A. Parke +3 more
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SERPINB7 maintains skin barrier by regulating protein O-GalNAc glycosylation [PDF]
Cell Death DiscoveryThe skin barrier is crucial for protecting against environmental challenges, preventing water loss, and regulating immune responses. This study aims to investigate the roles and mechanisms of SERPINB7 in skin barrier maintenance.
Rui Ma +6 more
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Skin Barrier Function and the Microbiome
International Journal of Molecular Sciences, 2022 Human skin is the largest organ and serves as the first line of defense against environmental factors. The human microbiota is defined as the total microbial community that coexists in the human body, while the microbiome refers to the collective genome of these microorganisms.
Miri Kim, Hyun Ji Lee, Kim Miri
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Chronic kidney disease-associated pruritus: a perspective on skin barrier damage [PDF]
Renal FailureChronic kidney disease-associated pruritus (CKD-aP) is a common complication in patients with end-stage kidney disease (ESKD) that seriously affects quality of life.
Fanzhou Zeng +4 more
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Skin Barrier Repair and Nursing Care in Patients with Atopic Dermatitis: A Narrative Review [PDF]
International Journal of General MedicineXue Chen School of Medicine, Lishui University, Lishui, Zhejiang, People’s Republic of ChinaCorrespondence: Xue Chen, Email 2665579339@qq.comAbstract: Atopic dermatitis (AD) is a chronic, relapsing inflammatory skin disorder characterized by impaired ...
Chen X
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