Results 1 to 10 of about 31,716 (293)

Ceramides during Pregnancy and Obstetrical Adverse Outcomes

Metabolites, 2023
Ceramides are a group of sphingolipids located in the external plasma membrane layer and act as messengers in cellular pathways such as inflammatory processes and apoptosis.
Dimitrios Goulis, Theofanis Vavilis
exaly   +4 more sources

Assessment of plasma ceramides as predictor for subclinical atherosclerosis [PDF]

Atherosclerosis Plus, 2021
Background and aims: Ceramides have been identified as novel biomarkers for cardiovascular disease (CVD) related events and mortality but their role in etiology of subclinical atherosclerosis is unknown.
Pashupati P. Mishra, Binisha H. Mishra, Leo-Pekka Lyytikäinen, Mika Hilvo, Markus Juonala, Mika Kähönen, Nina Hutri-Kähönen, Dimitrios I. Fotiadis, Olli T. Raitakari, Reijo Laaksonen, Terho Lehtimäki   +10 more
doaj   +3 more sources

Elevated Circulating Ceramides 18:0 and 24:1 as a Risk Factor for Sarcopenia: In Vitro, Animal, and Clinical Evidence [PDF]

Journal of Cachexia, Sarcopenia and Muscle
Background Ceramides have garnered considerable attention as pro‐aging bioactive lipids implicated in both metabolic dysfunction and musculoskeletal decline.
So Jeong Park, Ji Yeon Baek, Shibo Wei, Jin Young Lee, Yuna Lee, Sang‐Hoon Lee, Il‐Young Jang, Hyuk Sakong, Hyun Ju Yoo, Hee‐Won Jung, Eunju Lee, Su Jung Kim, Yunju Jo, Kyunggon Kim, Dongryeol Ryu, Beom‐Jun Kim   +15 more
doaj   +2 more sources

Influenza A Virus Infection Induces Preferential Increases in Long-Chain Ceramides [PDF]

Viruses
Influenza is a persistent public health concern worldwide. The elucidation of influenza A virus (IAV)–host interactions and the identification of host factors that regulate IAV infection would be beneficial for combating and treating the disease ...
Savannah McKenna, Kwang Il Jung, Barbara Sumner, Jennifer J. Wolf, Lloyd W. Sumner, Bumsuk Hahm   +5 more
doaj   +2 more sources

Infusion of C20:0 ceramide into ventral hippocampus triggers anhedonia-like behavior in female and male rats

Frontiers in Behavioral Neuroscience, 2022
Increased long-chain C20:0 ceramides have been found in the serum of patients with depression. Moreover, ceramides are linked with increased microglia reactivity and inflammatory cytokine production, which are associated with depression.
Lubriel Sambolín-Escobales, Adariana Feliciano-Quiñones, Lizmarie Tirado-Castro, Cristina Suárez, Dariangelly Pacheco-Cruz, Nashaly Irizarry-Méndez, Wilfred Fonseca-Ferrer, Anixa Hernández-López, María Colón-Romero, James T. Porter   +9 more
doaj   +1 more source

Role of Ceramides in the Molecular Pathogenesis and Potential Therapeutic Strategies of Cardiometabolic Diseases: What we Know so Far

Frontiers in Cell and Developmental Biology, 2022
Ceramides represent a class of biologically active lipids that are involved in orchestrating vital signal transduction pathways responsible for regulating cellular differentiation and proliferation. However, accumulating clinical evidence have shown that
Youssef M. Shalaby, Youssef M. Shalaby, Anas Al Aidaros, Anjana Valappil, Bassam R. Ali, Bassam R. Ali, Nadia Akawi, Nadia Akawi   +7 more
doaj   +1 more source

High-Fat Diet and Short-Term Unpredictable Stress Increase Long-Chain Ceramides Without Enhancing Behavioral Despair

Frontiers in Molecular Biosciences, 2022
Clinical and preclinical studies suggest that increases in long-chain ceramides in blood may contribute to the development of depressive-like behavior.
Lubriel Sambolín-Escobales, Lizmarie Tirado-Castro, Cristina Suarez, Dariangelly Pacheco-Cruz, Wilfred Fonseca-Ferrer, Pragney Deme, Norman Haughey, Gladys Chompre, James T. Porter   +8 more
doaj   +1 more source

Comparative profiling and comprehensive quantification of stratum corneum ceramides in humans and mice by LC/MS/MS[S]

Journal of Lipid Research, 2020
Ceramides are the predominant lipids in the stratum corneum (SC) and are crucial components for normal skin barrier function. Although the composition of various ceramide classes in the human SC has been reported, that in mice is still unknown, despite ...
Momoko Kawana, Masatoshi Miyamoto, Yusuke Ohno, Akio Kihara   +3 more
doaj   +1 more source

Neutral Ceramidase Is Required for the Reproduction of Brown Planthopper, Nilaparvata lugens (Stål)

Frontiers in Physiology, 2021
Ceramides are bioactive sphingolipids that have been implicated in insect development; however, their role in insect reproduction remains poorly understood.
Xiao-Xiao Shi, Mu-Fei Zhu, Ni Wang, Yuan-Jie Huang, Yuan-Jie Huang, Min-Jing Zhang, Chao Zhang, Soomro A. Ali, Wen-Wu Zhou, Chuanxi Zhang, Cungui Mao, Zeng-Rong Zhu, Zeng-Rong Zhu   +12 more
doaj   +1 more source

The Role of Ceramides in Diabetes and Cardiovascular Disease Regulation of Ceramides by Adipokines

Frontiers in Endocrinology, 2020
Metabolic dysfunction is intertwined with the pathophysiology of both diabetes and cardiovascular disease. Recently, one particular lipid class has been shown to influence the development and sustainment of these diseases: ceramides.
Bianca C. Field, Ruth Gordillo, Philipp E. Scherer, Philipp E. Scherer   +3 more
doaj   +1 more source