Results 11 to 20 of about 29,498 (282)
Frontiers in Behavioral Neuroscience, 2022 Increased long-chain C20:0 ceramides have been found in the serum of patients with depression. Moreover, ceramides are linked with increased microglia reactivity and inflammatory cytokine production, which are associated with depression.
Lubriel Sambolín-Escobales +9 more
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Serum ceramides in early pregnancy as predictors of gestational diabetes [PDF]
, 2023 Ceramides contribute to the development of type 2 diabetes but it is uncertain whether they predict gestational diabetes (GDM). In this multicentre case–control study including 1040 women with GDM and 958 non-diabetic controls, early pregnancy (mean 10.7
Laivuori, Hannele +31 more
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Frontiers in Molecular Biosciences, 2022 Clinical and preclinical studies suggest that increases in long-chain ceramides in blood may contribute to the development of depressive-like behavior.
Lubriel Sambolín-Escobales +8 more
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Frontiers in Cell and Developmental Biology, 2022 Ceramides represent a class of biologically active lipids that are involved in orchestrating vital signal transduction pathways responsible for regulating cellular differentiation and proliferation. However, accumulating clinical evidence have shown that
Youssef M. Shalaby +7 more
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Ceramides as Novel Disease Biomarkers [PDF]
, 2022 S.20-32Ceramides are sphingolipids and integral components of the eukaryotic cell membrane. Apart from providing structural integrity, ceramides have also been shown to act as second messengers in cell signaling processes.
Schiffmann, S. +3 more
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Journal of Biological Chemistry, 2011 Intensive research over the past 2 decades has implicated ceramide in the regulation of several cell responses. However, emerging evidence points to dramatic complexities in ceramide metabolism and structure that defy the prevailing unifying hypothesis on ceramide function that is based on the understanding of ceramide as a single entity.
Yusuf A, Hannun, Lina M, Obeid
openaire +2 more sources
Journal of Lipid Research, 2020 Ceramides are the predominant lipids in the stratum corneum (SC) and are crucial components for normal skin barrier function. Although the composition of various ceramide classes in the human SC has been reported, that in mice is still unknown, despite ...
Momoko Kawana +3 more
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Neutral Ceramidase Is Required for the Reproduction of Brown Planthopper, Nilaparvata lugens (Stål)
Frontiers in Physiology, 2021 Ceramides are bioactive sphingolipids that have been implicated in insect development; however, their role in insect reproduction remains poorly understood.
Xiao-Xiao Shi +12 more
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Ceramide and ceramide 1-phosphate in health and disease [PDF]
Lipids in Health and Disease, 2010 AbstractSphingolipids are essential components of cell membranes, and many of them regulate vital cell functions. In particular, ceramide plays crucial roles in cell signaling processes. Two major actions of ceramides are the promotion of cell cycle arrest and the induction of apoptosis.
Gómez-Muñoz Antonio +4 more
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The Role of Ceramides in Diabetes and Cardiovascular Disease Regulation of Ceramides by Adipokines
Frontiers in Endocrinology, 2020 Metabolic dysfunction is intertwined with the pathophysiology of both diabetes and cardiovascular disease. Recently, one particular lipid class has been shown to influence the development and sustainment of these diseases: ceramides.
Bianca C. Field +3 more
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