Results 11 to 20 of about 32,676 (287)

Assessment of plasma ceramides as predictor for subclinical atherosclerosis [PDF]

Atherosclerosis Plus, 2021
Background and aims: Ceramides have been identified as novel biomarkers for cardiovascular disease (CVD) related events and mortality but their role in etiology of subclinical atherosclerosis is unknown.
Hilvo, Mika, Mishra, Binisha H., Lyytikäinen, Leo-Pekka, Juonala, Markus, Kähönen, Mika, Lyytikäinen, Leo Pekka, Laaksonen, Reijo, Lehtimäki, Terho, Raitakari, Olli T., Fotiadis, Dimitrios I., Mishra, Pashupati P., Hilvo, Mika; id_orcid, Hutri-Kähönen, Nina, Olli T. Raitakari, Kähönen Mika, Raitakari Olli T., Fotiadis Dimitrios I., Mika Hilvo, Mika Kähönen, Laaksonen Reijo, Juonala Markus, Lehtimäki Terho, Reijo Laaksonen, Pashupati P. Mishra, Lyytikäinen Leo-Pekka, Hilvo Mika, Nina Hutri-Kähönen, Mishra Pashupati P., Markus Juonala, Hutri-Kähönen Nina, Mishra Binisha H., Leo-Pekka Lyytikäinen, Terho Lehtimäki, Dimitrios I. Fotiadis, Binisha H. Mishra   +34 more
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Ceramides and ceramide synthases in cancer: Focus on apoptosis and autophagy

European Journal of Cell Biology, 2023
Different studies corroborate a role for ceramide synthases and their downstream products, ceramides, in modulation of apoptosis and autophagy in the context of cancer. These mechanisms of regulation, however, appear to be context dependent in terms of ceramides' fatty acid chain length, subcellular localization, and the presence or absence of their ...
Javad Alizadeh, Simone C. da Silva Rosa, Xiaohui Weng, Joadi Jacobs, Shahrokh Lorzadeh, Amir Ravandi, Rui Vitorino, Stevan Pecic, Aleksandra Zivkovic, Holger Stark, Shahla Shojaei, Saeid Ghavami   +11 more
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Ceramides during Pregnancy and Obstetrical Adverse Outcomes

Metabolites, 2023
Ceramides are a group of sphingolipids located in the external plasma membrane layer and act as messengers in cellular pathways such as inflammatory processes and apoptosis.
Dimitrios G. Goulis, Theofanis Vavilis, Vikentia C. Harizopoulou, Maria Lantzanaki, Dimitrios Vavilis, Helen Bili   +5 more
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Blood-brain barrier permeability analysis of plant ceramides

PLoS ONE, 2020
Ceramides, a type of sphingolipid, are cell membrane components and lipid mediators that modulate a variety of cell functions. In plants, ceramides are mostly present in a glucosylated glucosylceramide (GlcCer) form.
Kohei Yuyama, Eguchi, Koichi, Takahashi, Kaori, Mukai, Katsuyuki, Yasuyuki Igarashi, Kaori Takahashi, Tsumita, Takuya, Daisuke Mikami, Takuya Tsumita, Sun, Hui, Hui Sun, Igarashi, Yasuyuki, Mikami, Daisuke, Koichi Eguchi, Yuyama, Kohei, Katsuyuki Mukai   +15 more
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Ceramides: focus on obesity [PDF]

Ожирение и метаболизм, 2020
It is generally known that obesity increases the risk of developing cardiovascular disease. A pathological increase in the mass of adipose tissue leads to a violation of the control of lipid accumulation at the molecular level, abnormal lipid metabolism ...
Yulia A. Dyleva, Ekaterina V. Belik, Olga V. Gruzdeva   +2 more
core   +3 more sources

Comparative profiling and comprehensive quantification of stratum corneum ceramides in humans and mice by LC/MS/MS[S] [PDF]

Journal of Lipid Research, 2020
Ceramides are the predominant lipids in the stratum corneum (SC) and are crucial components for normal skin barrier function. Although the composition of various ceramide classes in the human SC has been reported, that in mice is still unknown, despite ...
Ohno, Yusuke, Kawana, Momoko, Miyamoto, Masatoshi, Kihara, Akio   +3 more
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Ceramides and phospholipids in plasma extracellular vesicles are associated with high risk of major cardiovascular events after carotid endarterectomy [PDF]

Scientific Reports, 2022
Ceramides and phosphatidylcholines (PCs) are bioactive lipids and lipid bilayer membrane components. Distinct ceramides/PCs (ratios) predict cardiovascular outcome in patients with coronary artery disease.
de Borst, Gert J., Hilvo, Mika, van Bennekom, Joelle, Jylhä, Antti, Timmerman, Nathalie, de Winter, Robbert J., Waissi, Farahnaz, Pasterkamp, Gerard, Laaksonen, Reijo, de Kleijn, Dominique P.V., Dekker, Mirthe, Zorgeenheid Vaatchirurgie Medisch, Regenerative Medicine and Stem Cells, Brain, Infection & Immunity, Centraal Diagnostisch Laboratorium, Circulatory Health, Joelle van Bennekom, Farahnaz Waissi, Antti Jylhä, Gerard Pasterkamp, Mika Hilvo, Nathalie Timmerman, Reijo Laaksonen, Mirthe Dekker, Dominique P. V. de Kleijn, Gert J. de Borst, Robbert J. de Winter   +27 more
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Circulating ceramides as biomarkers of cardiovascular disease: evidence from phenotypic and genomic studies. [PDF]

, 2021
There is a need for new biomarkers of atherosclerotic cardiovascular disease (ACVD), the main cause of death globally. Ceramides, a class of potent bioactive lipid mediators, have signalling roles in apoptosis, cellular stress and inflammation.
Nicolaou, Anna; id_orcid, Keavney, Bernard, McGurk, Kathryn; id_orcid   +2 more
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The Role of Ceramides in Metabolic and Cardiovascular Diseases

Journal of Cardiovascular Development and Disease
Ceramides are bioactive sphingolipids increasingly recognized as mediators of cardiometabolic disease and residual cardiovascular risk. Accumulating evidence from experimental and clinical studies indicates that specific ceramide species contribute to ...
Idalia Garza-Veloz, Margarita L. Martinez-Fierro, Manuel Gonzalez-Plascencia, Garza-Veloz, Idalia, Martinez-Fierro, Margarita L., Flores-Morales, Virginia, Virginia Flores-Morales, Gonzalez-Plascencia, Manuel   +7 more
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Infusion of C20:0 ceramide into ventral hippocampus triggers anhedonia-like behavior in female and male rats

Frontiers in Behavioral Neuroscience, 2022
Increased long-chain C20:0 ceramides have been found in the serum of patients with depression. Moreover, ceramides are linked with increased microglia reactivity and inflammatory cytokine production, which are associated with depression.
Lubriel Sambolín-Escobales, Adariana Feliciano-Quiñones, Lizmarie Tirado-Castro, Cristina Suárez, Dariangelly Pacheco-Cruz, Nashaly Irizarry-Méndez, Wilfred Fonseca-Ferrer, Anixa Hernández-López, María Colón-Romero, James T. Porter   +9 more
doaj   +1 more source