Results 11 to 20 of about 41,371 (294)
Influenza A Virus Infection Induces Preferential Increases in Long-Chain Ceramides [PDF]
VirusesInfluenza is a persistent public health concern worldwide. The elucidation of influenza A virus (IAV)–host interactions and the identification of host factors that regulate IAV infection would be beneficial for combating and treating the disease ...
Savannah McKenna +5 more
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The Role of Ceramides in Metabolic and Cardiovascular Diseases [PDF]
Journal of Cardiovascular Development and DiseaseCeramides are bioactive sphingolipids increasingly recognized as mediators of cardiometabolic disease and residual cardiovascular risk. Accumulating evidence from experimental and clinical studies indicates that specific ceramide species contribute to ...
Manuel Gonzalez-Plascencia +3 more
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Optical manipulation of sphingolipid biosynthesis using photoswitchable ceramides [PDF]
eLife, 2019 Ceramides are central intermediates of sphingolipid metabolism that also function as potent messengers in stress signaling and apoptosis. Progress in understanding how ceramides execute their biological roles is hampered by a lack of methods to ...
Matthijs Kol +9 more
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Mitochondria-specific photorelease of ceramide induces apoptosis [PDF]
Journal of Lipid ResearchDeciphering the mechanisms by which bioactive intermediates of lipid metabolism influence cell behavior is a challenging task. We previously demonstrated that de novo synthesized ceramides are authentic transducers of apoptosis and that their CERT ...
Christian Schröer +5 more
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Frontiers in Behavioral Neuroscience, 2022 Increased long-chain C20:0 ceramides have been found in the serum of patients with depression. Moreover, ceramides are linked with increased microglia reactivity and inflammatory cytokine production, which are associated with depression.
Lubriel Sambolín-Escobales +9 more
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Assessment of plasma ceramides as predictor for subclinical atherosclerosis
Atherosclerosis Plus, 2021 Background and aims: Ceramides have been identified as novel biomarkers for cardiovascular disease (CVD) related events and mortality but their role in etiology of subclinical atherosclerosis is unknown.
Pashupati P. Mishra +10 more
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Ceramides during Pregnancy and Obstetrical Adverse Outcomes
Metabolites, 2023 Ceramides are a group of sphingolipids located in the external plasma membrane layer and act as messengers in cellular pathways such as inflammatory processes and apoptosis.
Maria Lantzanaki +5 more
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Journal of Biological Chemistry, 2011 Intensive research over the past 2 decades has implicated ceramide in the regulation of several cell responses. However, emerging evidence points to dramatic complexities in ceramide metabolism and structure that defy the prevailing unifying hypothesis on ceramide function that is based on the understanding of ceramide as a single entity.
Yusuf A, Hannun, Lina M, Obeid
openaire +2 more sources
Frontiers in Cell and Developmental Biology, 2022 Ceramides represent a class of biologically active lipids that are involved in orchestrating vital signal transduction pathways responsible for regulating cellular differentiation and proliferation. However, accumulating clinical evidence have shown that
Youssef M. Shalaby +7 more
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Frontiers in Molecular Biosciences, 2022 Clinical and preclinical studies suggest that increases in long-chain ceramides in blood may contribute to the development of depressive-like behavior.
Lubriel Sambolín-Escobales +8 more
doaj +1 more source