Results 21 to 30 of about 32,676 (287)

Serum ceramides in early pregnancy as predictors of gestational diabetes [PDF]

, 2023
Ceramides contribute to the development of type 2 diabetes but it is uncertain whether they predict gestational diabetes (GDM). In this multicentre case–control study including 1040 women with GDM and 958 non-diabetic controls, early pregnancy (mean 10.7
Laivuori, Hannele, Pouta, Anneli, Antti Jylhä, Mustaniemi, Sanna, Laaksonen, Reijo, Hanna Öhman, Tuija Männistö, Kajantie, Eero, Sanna Mustaniemi, Marja Vääräsmäki, The FinnGeDi Study Group, Elina Keikkala, Anneli Pouta, Eero Kajantie, Eriksson, Johan G., Gissler, Mika, Reijo Laaksonen, Risto Kaaja, Vääräsmäki, Marja, Nurhonen, Markku, Johan G. Eriksson, Laure Morin-Papunen, Morin-Papunen, Laure, Markku Nurhonen, Kaaja, Risto, Männistö, Tuija, Jylhä, Antti, Keikkala, Elina, Hannele Laivuori, Mika Gissler, Kajantie, Eero Olavi, Öhman, Hanna, Eriksson, Johan   +32 more
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Role of Ceramides in the Molecular Pathogenesis and Potential Therapeutic Strategies of Cardiometabolic Diseases: What we Know so Far

Frontiers in Cell and Developmental Biology, 2022
Ceramides represent a class of biologically active lipids that are involved in orchestrating vital signal transduction pathways responsible for regulating cellular differentiation and proliferation. However, accumulating clinical evidence have shown that
Youssef M. Shalaby, Youssef M. Shalaby, Anas Al Aidaros, Anjana Valappil, Bassam R. Ali, Bassam R. Ali, Nadia Akawi, Nadia Akawi   +7 more
doaj   +1 more source

High-Fat Diet and Short-Term Unpredictable Stress Increase Long-Chain Ceramides Without Enhancing Behavioral Despair

Frontiers in Molecular Biosciences, 2022
Clinical and preclinical studies suggest that increases in long-chain ceramides in blood may contribute to the development of depressive-like behavior.
Lubriel Sambolín-Escobales, Lizmarie Tirado-Castro, Cristina Suarez, Dariangelly Pacheco-Cruz, Wilfred Fonseca-Ferrer, Pragney Deme, Norman Haughey, Gladys Chompre, James T. Porter   +8 more
doaj   +1 more source

Ceramide and ceramide 1-phosphate in health and disease [PDF]

Lipids in Health and Disease, 2010
AbstractSphingolipids are essential components of cell membranes, and many of them regulate vital cell functions. In particular, ceramide plays crucial roles in cell signaling processes. Two major actions of ceramides are the promotion of cell cycle arrest and the induction of apoptosis.
Gómez-Muñoz Antonio, Trueba Miguel, Ouro Alberto, Gangoiti Patricia, Arana Lide   +4 more
openaire   +4 more sources

Neutral Ceramidase Is Required for the Reproduction of Brown Planthopper, Nilaparvata lugens (Stål)

Frontiers in Physiology, 2021
Ceramides are bioactive sphingolipids that have been implicated in insect development; however, their role in insect reproduction remains poorly understood.
Xiao-Xiao Shi, Mu-Fei Zhu, Ni Wang, Yuan-Jie Huang, Yuan-Jie Huang, Min-Jing Zhang, Chao Zhang, Soomro A. Ali, Wen-Wu Zhou, Chuanxi Zhang, Cungui Mao, Zeng-Rong Zhu, Zeng-Rong Zhu   +12 more
doaj   +1 more source

The Role of Ceramides in Diabetes and Cardiovascular Disease Regulation of Ceramides by Adipokines

Frontiers in Endocrinology, 2020
Metabolic dysfunction is intertwined with the pathophysiology of both diabetes and cardiovascular disease. Recently, one particular lipid class has been shown to influence the development and sustainment of these diseases: ceramides.
Bianca C. Field, Ruth Gordillo, Philipp E. Scherer, Philipp E. Scherer   +3 more
doaj   +1 more source

Plasma ceramides are associated with MRI-based liver fat content but not with noninvasive scores of liver fibrosis in patients with type 2 diabetes

Cardiovascular Diabetology, 2023
Background There is growing evidence that ceramides play a significant role in the onset and progression of non-alcoholic fatty liver disease (NAFLD), a highly prevalent condition in patients with type 2 diabetes associated with hepatic and ...
Damien Denimal, Sarah Béland-Bonenfant, Jean-Paul Pais-de-Barros, Alexia Rouland, Benjamin Bouillet, Laurence Duvillard, Bruno Vergès, Jean-Michel Petit   +7 more
doaj   +1 more source

Identification and quantitation of free ceramides in human platelets

Journal of Lipid Research, 1972
Free ceramides were isolated from human platelets. Their structures were unequivocally determined by gas–liquid chromatography–mass spectrometry of the trimethylsilyl ether derivatives.
William Krivit, Sven Hammarström
doaj   +1 more source

Targeting Ceramides and Adiponectin Receptors in the Islet of Langerhans for Treating Diabetes

Molecules, 2022
Ceramides belong to the sphingolipid family and represent the central hub of the sphingolipid network. In obesity, oversupply of saturated fatty acids including palmitate raises ceramide levels which can be detrimental to cells.
Wen-hong Li
doaj   +1 more source

NA increased Ceramides in the epidermis.

, 2023
Ceramides were extracted from epidermis and subjected to LC/MS for determining the levels of each ceramide species. The amount of ceramide species in the HIEO (0.1%) or NA (0.03%) conditions is expressed as a percentage in comparison to the DMSO (0.5 ...
Valérie Cenizo (14716684), Alain Moga (14716681), Aurélie Pagnon (7049168), Malvina Olivero (14716675), Pascal Portes (14716687), Virginie Rouquet (14716678), Géraldine Lemaire (14716672)   +6 more
core   +1 more source