Results 31 to 40 of about 31,716 (293)
Fuse your mitochondria, lose appetite: an anorexic, anti‐obesity sphingolipid
EMBO Molecular Medicine, 2021 Aberrant production of ceramides, the precursors of complex sphingolipids, is a hallmark of obesity and strongly linked to metabolic dysfunction (Meikle and Summers 2017).
Carolin Muley, Alexander Bartelt
doaj +1 more source
Hepatology, EarlyView., 2022 NRPT 1X reduces ALT and ceramide 14:0 in 65% of subjects as compared to only 28% in the placebo group. Abstract Background and Aims The prevalence of NAFLD is increasing globally and on a path to becoming the most frequent cause of chronic liver disease. Strategies for the prevention and treatment of NAFLD are urgently needed.
Ryan W. Dellinger +7 more
wiley +1 more source
Ceramide Kinase and Ceramide‐1‐Phosphate
, 2007 It has been over a decade since the sphingolipid ceramide-1-phosphate (C1P) was described. Until recently, only sparse reports on possible biological functions for this lipid have been published. A large number of reports have now surfaced demonstrating distinct biological mechanisms regulated by C1P produced from ceramide kinase (CERK).
Dayanjan S, Wijesinghe +3 more
openaire +3 more sources
Novel ceramides recovered from Porphyromonas gingivalis: relationship to adult periodontitis
Journal of Lipid Research, 1998 The primary purpose of this study was to characterize the major structural features of ceramides recovered from Porphyromonas gingivalis, a suspected periodontal pathogen. Complex lipids extracted from P.
Frank C. Nichols
doaj +1 more source
NA increased Ceramides in the epidermis.
, 2023 Ceramides were extracted from epidermis and subjected to LC/MS for determining the levels of each ceramide species. The amount of ceramide species in the HIEO (0.1%) or NA (0.03%) conditions is expressed as a percentage in comparison to the DMSO (0.5 ...
Valérie Cenizo (14716684) +6 more
core +1 more source
Molecules, 2023 Ceramides have been associated with cardiometabolic disease (e.g., acute myocardial infarction (AMI) and type 2 diabetes (T2D)) and adverse outcomes. Acute admission hyperglycemia (AH) is a transient glucose alteration in response to stress.
Melania Gaggini +6 more
doaj +1 more source
Journal of Lipid Research, 1979 Reaction of ceramides containing nonhydroxy fatty acids with benzoyl chloride in pyridine at 70 degrees C for 1 hr resulted in N-benzoylation to form N,N-acyl,benzoyl derivatives; O-benzoylation also occurred.
M Iwamori, C Costello, H W Moser
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Ceramides are early responders in metabolic syndrome development in rhesus monkeys
Scientific Reports, 2022 Metabolic syndrome increases risk of complicating co-morbidities. Current clinical indicators reflect established metabolic impairment, preventing earlier intervention strategies.
Alex B. Smith +9 more
doaj +1 more source
Patologìâ, 2013 Introduction. Local therapy is an important method for treatment of dermatitis used to suppress the skin inflammation and the main related symptoms: hyperemia, edema, pruritus, lichenification etc.
Ya. O. Butko, Yu. B. Laryanovska
doaj +1 more source
Differential effects of ceramides upon adenylyl cyclase subtypes [PDF]
, 1998 Ceramides are reported to stimulate different effector systems, among them atypical protein kinases C (PKCs). When HEK 293 cells, stably expressing adenylyl cyclase type II (AC II), were treated with various ceramide derivatives, adenylyl cyclase ...
Angela Bösel +3 more
core +1 more source