Results 31 to 40 of about 32,676 (287)
Hepatology, EarlyView., 2022 Increased liver content of DHA‐derived small lipid autacoids (i.e resolvin D1 and maresin 1) associates with enhanced mitochondrial oxidative phosphorylation, fatty acid β‐oxidation and bioenergetic metabolic flux. These features provide hepatic protection from steatotic, pro‐inflammatory and fibrogenic insults.
Cristina López‐Vicario +12 more
wiley +1 more source
Hepatology, EarlyView., 2022 The role of SMLR1 in lipid metabolism (high fat + cholesterol diet in mice) Abstract Background and Aims The assembly and secretion of VLDL from the liver, a pathway that affects hepatic and plasma lipids, remains incompletely understood. We set out to identify players in the VLDL biogenesis pathway by identifying genes that are co‐expressed with the ...
Willemien van Zwol +22 more
wiley +1 more source
Hepatology, EarlyView., 2022 NRPT 1X reduces ALT and ceramide 14:0 in 65% of subjects as compared to only 28% in the placebo group. Abstract Background and Aims The prevalence of NAFLD is increasing globally and on a path to becoming the most frequent cause of chronic liver disease. Strategies for the prevention and treatment of NAFLD are urgently needed.
Ryan W. Dellinger +7 more
wiley +1 more source
Ceramide in the prostate [PDF]
Cancer Biology & Therapy, 2013 The nomenclature for the serine/threonine protein phosphatases was established by Professor Sir Philip Cohen over 30 years ago. (1) At that time protein phosphatase 1 was known to have two small inhibitory proteins (I-1 and I-2) and be regulated by sub-cellular location whereas no protein inhibitor had yet been discovered for the related multi-subunit ...
openaire +2 more sources
Journal of Lipid Research, 2022 Ceramides are essential lipids for skin permeability barrier function, and a wide variety of ceramide species exist in the stratum corneum (SC). Although ceramides with long-chain bases (LCBs) of various lengths have been identified in the human SC, a ...
Madoka Suzuki, Yusuke Ohno, Akio Kihara
doaj +1 more source
Ceramide Kinase and Ceramide‐1‐Phosphate
, 2007 It has been over a decade since the sphingolipid ceramide-1-phosphate (C1P) was described. Until recently, only sparse reports on possible biological functions for this lipid have been published. A large number of reports have now surfaced demonstrating distinct biological mechanisms regulated by C1P produced from ceramide kinase (CERK).
Dayanjan S, Wijesinghe +3 more
openaire +3 more sources
Fuse your mitochondria, lose appetite: an anorexic, anti‐obesity sphingolipid
EMBO Molecular Medicine, 2021 Aberrant production of ceramides, the precursors of complex sphingolipids, is a hallmark of obesity and strongly linked to metabolic dysfunction (Meikle and Summers 2017).
Carolin Muley, Alexander Bartelt
doaj +1 more source
Ceramides: a new player in the inflammation-insulin resistance paradigm? [PDF]
, 2009 No abstract ...
Sattar, N., Gill, J.M.R.
core +1 more source
Novel ceramides recovered from Porphyromonas gingivalis: relationship to adult periodontitis
Journal of Lipid Research, 1998 The primary purpose of this study was to characterize the major structural features of ceramides recovered from Porphyromonas gingivalis, a suspected periodontal pathogen. Complex lipids extracted from P.
Frank C. Nichols
doaj +1 more source
Ceramides and Ceramide Scores: Clinical Applications for Cardiometabolic Risk Stratification
Frontiers in Endocrinology, 2020 Ceramides are bioactive lipids that have an important role in many cellular functions such as apoptosis and inflammation. During the past decade emerging clinical data have shown that ceramides are not only of great biochemical interest but may also have
Mika Hilvo +5 more
doaj +1 more source