Results 41 to 50 of about 31,716 (293)

Ceramides: A potential therapeutic target in pulmonary emphysema [PDF]

, 2013
Background: The aim of this manuscript was to characterize airway ceramide profiles in a rodent model of elastase-induced emphysema and to examine the effect of pharmacological intervention directed towards ceramide metabolism.Methods: Adult mice were ...
Reiss, I.K.M. (Irwin), Johan C de Jongste, Reiss, Irwin, Jongste, J.C. (Johan) de, Jeroen Tibboel, Irwin Reiss, Jongste, Johan, Post, M.R. (Martin), Verhoef-Post, M, Martin Post, Tibboel, Jeroen   +10 more
core   +4 more sources

Metabolic Conversion of Ceramides in HeLa Cells - A Cholesteryl Phosphocholine Delivery Approach. [PDF]

PLoS ONE, 2015
Ceramides can be delivered to cultured cells without solvents in the form of complexes with cholesteryl phosphocholine. We have analysed the delivery of three different radiolabeled D-erythro-ceramides (C6-Cer, C10-Cer and C16-Cer) to HeLa cells, and ...
Matti A Kjellberg, Max Lönnfors, J Peter Slotte, Peter Mattjus   +3 more
doaj   +1 more source

Mild alkali-stable phospholipids in chicken egg yolks: characterization of 1-alkenyl and 1-alkyl-sn-glycero-3-phosphoethanolamine, sphingomyelin, and 1-alkyl-sn-glycero-3-phosphocholine

Journal of Lipid Research, 1980
Chicken egg yolk phospholipids were subjected to mild alkaline hydrolysis. The resulting alkali-stable phospholipids were characterized by chemical chromatographic, and enzymatic methods.
U H Do, S Ramachandran
doaj   +1 more source

Effect of metformin administration and weight loss on plasma ceramide C16:0, C18:0, C24:1 concentrations in patients with non-alcoholic fatty liver disease associated with insulin resistance and type 2 diabetes

Gastroenterologìa, 2020
Background. Ceramides are the fats of the sphingolipid family that are involved in the development of insulin resistance, non-alcoholic fatty liver disease, and type 2 diabetes.
L.L. Pavlovskyi
doaj   +1 more source

Plasma Ceramides

, 2018
Objective— Ceramides are sphingolipids involved with cellular signaling. Synthesis of ceramides occurs in all tissues. Ceramides accumulate within tissues and the blood plasma during metabolic dysfunction, dyslipidemia, and ...
Linnea M. Baudhuin, Allan S. Jaffe, Jeffrey W. Meeusen, Sandra C. Bryant, Peter B. Berger, Leslie J. Donato   +5 more
core   +1 more source

A method for the quantitative determination of neutral glycosphingolipids in urine sediment

Journal of Lipid Research, 1970
A method is described for the isolation and quantitation of six neutral glycosyl ceramides from human urinary sediment. Total lipids were extracted from sediments of 24-hr urine collections, and the glycosyl ceramides were isolated by silicic acid column
R.J. Desnick, C.C. Sweeley, W. Krivit
doaj   +1 more source

Plasma Ceramides as Prognostic Biomarkers and Their Arterial and Myocardial Tissue Correlates in Acute Myocardial Infarction

JACC: Basic to Translational Science, 2018
Summary: We identified a plasma signature of 11 C14 to C26 ceramides and 1 C16 dihydroceramide predictive of major adverse cardiovascular events in patients with acute myocardial infarction (AMI). Among patients undergoing coronary artery bypass surgery,
Leonardo P. de Carvalho, MD, PhD, Sock Hwee Tan, PhD, Ghim-Siong Ow, BSc, Zhiqun Tang, PhD, Jianhong Ching, PhD, Jean-Paul Kovalik, MD, PhD, Sock Cheng Poh, BSc, Chee-Tang Chin, MBBS, A. Mark Richards, MD, PhD, Eliana C. Martinez, MD, PhD, Richard W. Troughton, MD, PhD, Alan Yean-Yip Fong, MBBS, Bryan P. Yan, MBBS, Aruni Seneviratna, MBBS, MPH, Vitaly Sorokin, MD, PhD, Scott A. Summers, PhD, Vladimir A. Kuznetsov, PhD, SciD, Mark Y. Chan, MBBS, PhD   +17 more
doaj   +1 more source

Ceramides stimulate caspase-14 expression in human keratinocytes. [PDF]

, 2013
Caspase-14 is an enzyme that is expressed predominantly in cornifying epithelia and catalyses the degradation of profilaggrin. Additionally, caspase-14 plays an important role in the terminal differentiation of keratinocytes.
Elias, Peter, Bikle, Daniel, Kim, Peggy, Feingold, Kenneth, Jiang, Yan, Grunfeld, Carl, Uchida, Yoshikazu   +6 more
core   +1 more source

Serum Ceramides and Type 2 Diabetes Are Mutually Independent Predictors of Cardiovascular Events in Patients With Peripheral Artery Disease

, 2019
Introduction: Ceramides are enriched in atherosclerotic plaques, and a set of circulating ceramides including Cer(d18:1/16:0), Cer(d18:1/18:0), Cer(d18:1/24:1), and Cer(d18:1/24:0) has recently emerged as predictors of cardiovascular outcomes in coronary
Christoph H, Saely, Dopheide, Jörn Fredrik, Baumgartner, Iris, Mita, Lääperi, Muendlein, Axel, Mader, Arthur, Reijo, Laaksonen, Fraunberger, Peter, Alexander, Vonbank, Leiherer, Andreas, Drexel, Heinz   +10 more
core   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source