Results 21 to 30 of about 1,669,596 (254)

Emollient enhancement of the skin barrier from birth offers effective atopic dermatitis prevention [PDF]

, 2014
BackgroundAtopic dermatitis (atopic eczema) is a chronic inflammatory skin disease that has reached epidemic proportions in children worldwide and is increasing in prevalence.
Cork, Michael J., Chen, Zunqiu, Simpson, Eric L., Chalmers, Joanne R., Hanifin, Jon M., Thomas, Kim S., McLean, W. H. Irwin, Chen, Yiyi, Williams, Hywel C., Brown, Sara J., McLean, W.H. Irwin, Irwin McLean, W.H.   +11 more
core   +1 more source

The Epidermal Barrier Structure and Function of Re-Harvested Skin from Non-Scalp Donor Sites

Journal of Investigative Surgery, 2023
Aim The aim of this study was to explore the epidermal barrier structure and function of re-harvested skin from non-scalp donor sites. Methods Six patients with large-area deep burns who met the inclusion and exclusion criteria were subjected to split ...
Bohan Zhang, Peng Luo, Jiachen Sun, Dawei Li, Zhaoxing Liu, Xinzhu Liu, Hongqing Zhao, Zhisheng Li, Xiaoye Xie, Jianqiu Yang, Chuan’an Shen   +10 more
doaj   +1 more source

The effect of washing and drying practices on skin barrier function [PDF]

, 2008
Purpose: The aim of this study was to explore the potential contribution to skin damage caused by standard washing and drying techniques used in nursing.Design: An experimental cohort design was used, with healthy volunteers (n = 15) receiving 6 ...
David Voegeli, Voegeli, D.
core   +1 more source

Skin Microbiome Composition and Key Factors of its Barrier Function

Вопросы современной педиатрии, 2023
The skin is the largest organ of the human body, it creates protective barrier between the internal and external environment. Skin barrier damage may result in homeostasis imbalance, inflammation, or bacterial infection.
Nikolay N. Murashkin, Ekaterina S. Pavlova, Roman V. Epishev, Alexander I. Materikin, Roman A. Ivanov, Alena A. Savelova, Dmitriy V. Fedorov, Maria A. Leonova   +7 more
doaj   +1 more source

Impact of Age and Body Site on Adult Female Skin Surface pH [PDF]

, 2012
Background: pH is known as an important parameter in epidermal barrier function and homeostasis. Aim: The impact of age and body site on skin surface pH (pH(SS)) of women was evaluated in vivo.
Korting, Hans Christian, Meier, Robert Johannes, Landthaler, Michael, Schreml, Stephan, Zeller, Veronika, Babilas, Philipp, Korting, H. C., Behm, Barbara   +7 more
core   +1 more source

Lysosphingolipids in ceramide-deficient skin lipid models

Journal of Lipid Research
Ceramides are key components of the skin's permeability barrier. In atopic dermatitis, pathological hydrolysis of ceramide precursors - glucosylceramides and sphingomyelin - into lysosphingolipids, specifically glucosylsphingosine (GS) and sphingosine ...
Georgios Paraskevopoulos, Lukáš Opálka, Andrej Kováčik, Anna Paraskevopoulou, Eleni Panoutsopoulou, Irene Sagrafena, Petra Pullmannová, Robert Čáp, Kateřina Vávrová   +8 more
doaj   +1 more source

Revealing the Correlation between Altered Skin Lipids Composition and Skin Disorders

Cosmetics, 2021
Human skin layers serve as a barrier between the body and the environment, by preventing water loss and blocking the entry of chemicals, allergens, and microbes.
Katerina Drakou, Andrea Tsianni, Faye Vrani, Valia Kefala, Efstathios Rallis   +4 more
doaj   +1 more source

Filaggrin-stratified transcriptomic analysis of pediatric skin identifies mechanistic pathways in patients with atopic dermatitis [PDF]

, 2014
Background: Atopic dermatitis (AD; eczema) is characterized by a widespread abnormality in cutaneous barrier function and propensity to inflammation. Filaggrin is a multifunctional protein and plays a key role in skin barrier formation.
Sherstnev, Alexander, O'Regan, Grainne M., Schurch, Nicholas J., Barton, Geoffrey J., Sandilands, Aileen, Irvine, Alan D., Brown, Sara J., Kroboth, Karin, Cole, Christian, Cole, Christian; id_orcid, Watson, Rosemarie M., Barton, Geoffrey J.; id_orcid, McLean, W. H. Irwin, Irwin McLean, W.H.   +13 more
core   +1 more source

Impact of Radiation Therapy on Physical and Psychosocial Health of Adolescents and Young Adults: A Joint Report From the Children's Oncology Group AYA and Radiation Oncology Committees

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Rates of cancer among adolescents and young adults (AYA), age 15–39 years, are increasing. Consequently, radiation oncologists are treating more AYAs who have diagnoses spanning both pediatric and adult practices. Compared to pediatric and older adult patients, AYAs face a unique set of challenges.
Hesham Elhalawani, Rachel K. Peterson, Avani D. Rao, Laurie J. McKenzie, Ahmed Magdy Elmotayam, Leslie Chang, Michael Roth, Susan L. McGovern   +7 more
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source