Results 1 to 10 of about 6,511,959 (301)

Enhancing Extracellular Adenosine Levels Restores Barrier Function in Acute Lung Injury Through Expression of Focal Adhesion Proteins

Frontiers in Molecular Biosciences, 2021
Background: Acute respiratory distress syndrome (ARDS) is a clinical presentation of acute lung injury (ALI) with often fatal lung complication. Adenosine, a nucleoside generated following cellular stress provides protective effects in acute injury.
Wei Wang, Ning-yuan Chen, Dewei Ren, Jonathan Davies, Kemly Philip, Holger K. Eltzschig, Michael R. Blackburn, Michael R. Blackburn, Bindu Akkanti, Harry Karmouty-Quintana, Harry Karmouty-Quintana, Harry Karmouty-Quintana, Tingting Weng, Tingting Weng   +13 more
doaj   +1 more source

Busemann Functions and Barrier Functions [PDF]

Acta Applicandae Mathematicae, 2017
We show that Busemann functions on a smooth, non-compact, complete, boundaryless, connected Riemannian manifold are viscosity solutions with respect to the Hamilton-Jacobi equation determined by the Riemannian metric and consequently they are locally semi-concave with linear modulus.
Cui, Xiaojun, Cheng, Jian
openaire   +2 more sources

Sucrose-induced hyperglycemia dysregulates intestinal zinc metabolism and integrity: risk factors for chronic diseases

Frontiers in Nutrition, 2023
ObjectiveZinc is an essential micronutrient that is critical for many physiological processes, including glucose metabolism, regulation of inflammation, and intestinal barrier function.
Samuel Blake Mitchell, Yu-Han Hung, Yu-Han Hung, Trista Lee Thorn, Jiaqi Zou, Filiz Baser, Sukru Gulec, Celeste Cheung, Tolunay Beker Aydemir   +8 more
doaj   +1 more source

Barrier Function at HMR [PDF]

Molecular Cell, 2005
The silenced HMR domain is restricted from spreading by barrier elements, and the right barrier is a unique t-RNA(THR) gene. We show that sequences immediately flanking the silenced domain were enriched in acetylated, but not methylated, histones, whereas the barrier element was associated with a nucleosome-free region.
Oki, Masaya, Kamakaka, Rohinton T.
openaire   +2 more sources

Plasmodium falciparum and TNF-α Differentially Regulate Inflammatory and Barrier Integrity Pathways in Human Brain Endothelial Cells

mBio, 2022
Cerebral malaria is a severe complication of Plasmodium falciparum infection characterized by the loss of blood-brain barrier (BBB) integrity, which is associated with brain swelling and mortality in patients. P.
Marisol Zuniga, Claudia Gomes, Ze Chen, Criseyda Martinez, Joseph Cooper Devlin, P’ng Loke, Ana Rodriguez   +6 more
doaj   +1 more source

Fumonisin B₁ Inhibits Cell Proliferation and Decreases Barrier Function of Swine Umbilical Vein Endothelial Cells

Toxins, 2021
The fumonisins are a group of common mycotoxins found around the world that mainly contaminate maize. As environmental toxins, they pose a threat to human and animal health. Fumonisin B1 (FB1) is the most widely distributed and the most toxic.
Qing Li, Qiaoling Yuan, Tianjie Wang, Yang Zhan, Lingchen Yang, Ying Fan, Hongyu Lei, Jianming Su   +7 more
doaj   +1 more source

A Protective Role of FAM13A in Human Airway Epithelial Cells Upon Exposure to Cigarette Smoke Extract

Frontiers in Physiology, 2021
BackgroundChronic Obstructive Pulmonary Disease (COPD) is a progressive lung disease characterized by chronic inflammation upon inhalation of noxious particles, e.g., cigarette smoke.
Qing Chen, Qing Chen, Maaike de Vries, Maaike de Vries, Kingsley Okechukwu Nwozor, Kingsley Okechukwu Nwozor, Jacobien A. Noordhoek, Jacobien A. Noordhoek, Jacobien A. Noordhoek, Corry-Anke Brandsma, Corry-Anke Brandsma, H. Marike Boezen, H. Marike Boezen, Irene H. Heijink, Irene H. Heijink, Irene H. Heijink   +15 more
doaj   +1 more source

Effects of Bacillus licheniformis and Bacillus subtilis on Gut Barrier Function, Proinflammatory Response, ROS Production and Pathogen Inhibition Properties in IPEC-J2—Escherichia coli/Salmonella Typhimurium Co-Culture

Microorganisms, 2022
The emergence of antimicrobial resistance raises serious concerns worldwide. Probiotics offer a promising alternative to enhance growth promotion in farm animals; however, their mode of action still needs to be elucidated.
Nikolett Palkovicsné Pézsa, Dóra Kovács, Bence Rácz, Orsolya Farkas   +3 more
doaj   +1 more source

Desmosomes as Signaling Hubs in the Regulation of Cell Behavior

Frontiers in Cell and Developmental Biology, 2021
Desmosomes are intercellular junctions, which preserve tissue integrity during homeostatic and stress conditions. These functions rely on their unique structural properties, which enable them to respond to context-dependent signals and transmit them to ...
Lisa Müller, Mechthild Hatzfeld, René Keil   +2 more
doaj   +1 more source

Plant essential oils improve growth performance by increasing antioxidative capacity, enhancing intestinal barrier function, and modulating gut microbiota in Muscovy ducks

Poultry Science, 2023
: Essential oils (EO) are known for their antioxidant, anti-inflammatory, antimicrobial, and growth-promoting properties. However, data rgarding their impact on the intestinal health and gut microbiota of ducks remain limited.
Chaoyue Ge, Xinyu Luo, Lianchi Wu, Yujie Lv, Zhaoying Hu, Dongyou Yu, Bing Liu   +6 more
doaj   +1 more source