Results 231 to 240 of about 467,385 (295)

Continuous Subcutaneous Apomorphine as a Temporary Bridging Therapy for Dopamine Dysregulation Syndrome in Patients with Deep Brain Stimulation

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Dopamine dysregulation syndrome (DDS) is a challenging complication of dopaminergic therapy in Parkinson's disease and can persist despite subthalamic deep brain stimulation (STN‐DBS). We evaluated a temporary bridging concept in which oral dopaminergic medication was replaced by continuous subcutaneous apomorphine infusion while ...
Tobias Binder   +8 more
wiley   +1 more source

When Tics and Autism Meet: Phenomenology, Severity, and Treatment Patterns

open access: yesMovement Disorders Clinical Practice, EarlyView.
ABSTRACT Background Tic disorders frequently co‐occur with neurodevelopmental conditions, including autism spectrum disorder (ASD). However, the impact of ASD on tic phenomenology, severity, and treatment patterns remains incompletely understood. Objectives To compare clinical characteristics, tic phenomenology, severity, and treatment patterns in ...
Fatimah Aldurayhim   +3 more
wiley   +1 more source

Alexithymia and non-suicidal self-ınjury in adolescents: the roles of emotion dysregulation, impulsivity, and self-esteem. [PDF]

open access: yesBMC Psychiatry
Yenen Menderes AS   +5 more
europepmc   +1 more source

Toxicity Differences Between Microplastics and Nanoplastics in Organs: From Molecular Mechanisms to Potential Therapeutic Strategies

open access: yesMed Research, EarlyView.
This review systematically compares the size‐dependent toxicity of microplastics and nanoplastics in the intestine, liver, kidney, lung, and brain. Particle size determines bioavailability, barrier penetration, and injury mechanisms. Because of their small size and high surface reactivity, NPs readily cross the intestinal epithelium and blood–brain ...
Yixian Cheng   +14 more
wiley   +1 more source

Dietary Fatty Acids, Cardiovascular Disease, and Life Expectancy Among Adults With Adverse Mental Health‐Related Characteristics: A Cohort‐Based Target Trial Emulation Study

open access: yesMed Research, EarlyView.
This study highlights the cardiovascular and longevity benefits of dietary n‐3 PUFAs in individuals with adverse mental health‐related characteristics, particularly ALA and EPA. The target trial emulation framework further provides evidence, revealing EPA and DHA are associated with a lower early‐onset CVD risk in loneliness, while ALA and EPA are ...
Li Chen   +9 more
wiley   +1 more source

Apathy in Lewy Body Disorders: A Position Paper

open access: yesMovement Disorders, EarlyView.
Abstract Apathy is one of the most prevalent and disabling non‐motor symptoms in Parkinson's disease (PD) and dementia with Lewy bodies (DLB), collectively referred to as Lewy body disorders (LBDs). It is associated with reduced quality of life, accelerated cognitive decline, increased caregiver burden, and poorer functional outcomes, yet remains ...
Jaime Kulisevsky   +12 more
wiley   +1 more source

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