Results 71 to 80 of about 125,087 (294)

Single‐Cell Atlas Reveals Tumorigenic Profiles and Immune Dynamics of Adrenal Incidentalomas

Advanced Science, EarlyView.
Single‐cell RNA sequencing reveals cellular heterogeneity in adrenal incidentalomas, identifying distinct tumor cell populations. Clusterin is recognized as a biomarker for adrenocortical tumors, correlating with established markers. MYCN‐positive clusters in pheochromocytomas indicated poorer survival.
Meng Wang, Guangmin Zheng, Xiaoyong Hu, Feng Tian, Tuo Li, Zheng Zhang, Kan Gong, Shiwei Chen, Lin Yuan, Yu Qi, Lin Li, Daofu Cheng, Liu Liu, Fuqiang Liu, Yujing Sun, Xiangdong Fang, Ruxing Zhao, Bing Liu, Chao Zhang   +18 more
wiley   +1 more source

A population‐based study of homelessness, antisocial behaviour and violence victimisation among young adults in Victoria, Australia

Australian Journal of Social Issues, Volume 57, Issue 4, Page 762-782, December 2022., 2022
Abstract Homeless young adults are at increased risk for contact with the police and are overrepresented in the justice system. This study explored associations between homelessness, antisocial behaviour and violence victimisation using longitudinal panel data gathered through young adulthood.
Jessica A. Heerde, Jennifer A. Bailey, George C. Patton, John W. Toumbourou   +3 more
wiley   +1 more source

Individual-specific change points in circadian rest-activity rhythm and sleep in individuals tapering their antidepressant medication: an actigraphy study

Scientific Reports
Group-level studies showed associations between depressive symptoms and circadian rhythm elements, though whether these associations replicate at the within-person level remains unclear.
Olga Minaeva, Evelien Schat, Eva Ceulemans, Yoram K. Kunkels, Arnout C. Smit, Marieke Wichers, Sanne H. Booij, Harriëtte Riese   +7 more
doaj   +1 more source

Simultaneous Reversal of T Lymphocytes and Cancer Cells Metabolism Via a Biomimetic Heavy‐Atom‐Free Photosensitizers‐Based Combination Therapies to Boost Cancer Photoimmunotherapy

Advanced Science, EarlyView.
This work develops a cyanine dye named Cy‐BF and encapsulates it with phospholipids and platelet exosome vesicles to create CHL. Characterized by high phototoxicity, low dark toxicity, and enhanced tumor targeting, CHL demonstrates aggregation‐induced broadening of absorption spectra and NIR‐activated photothermal therapy and type I photodynamic ...
Yongjian Zhang, Xiaohong Wu, Kaiyuan Wang, Yaohan Tang, Xiuxin Lu, Fusheng Sun, Hua Tang, Xiaoyuan Chen, Shipeng Ning   +8 more
wiley   +1 more source

Understanding the dynamics of support seeking in women with lived experience of non‐physical intimate partner violence (IPV) and the service responses—A qualitative study

Australian Journal of Social Issues, Volume 57, Issue 4, Page 861-879, December 2022., 2022
Abstract Non‐physical abuse is a form of intimate partner violence (IPV), which negatively impacts physical and mental well‐being. The study objectives were to understand the process of support seeking amongst women who experience non‐physical IPV. Interviews were conducted with women who have experience of non‐physical IPV and support workers.
Karishma Doolabh, Colleen Fisher, Melissa O'Donnell   +2 more
wiley   +1 more source

Externally validated clinical prediction models for estimating treatment outcomes for patients with a mood, anxiety or psychotic disorder: systematic review and meta-analysis

BJPsych Open
Background Suboptimal treatment outcomes contribute to the high disease burden of mood, anxiety or psychotic disorders. Clinical prediction models could optimise treatment allocation, which may result in better outcomes.
Desi G. Burghoorn, Sanne H. Booij, Robert A. Schoevers, Harriëtte Riese   +3 more
doaj   +1 more source

The Lung Microbiome Modulates Pain‐Like Behavior Via the Lung–Brain Axis in a Nitroglycerin‐Induced Chronic Migraine Mouse Model

Advanced Science, EarlyView.
Intratracheal neomycin alters pulmonary microbiota, activating the vagus nerve via lung brain‐derived neurotrophic factor/tropomyosin receptor kinase B (BDNF/TrkB) pathway, further projecting to nucleus of solitary tract (NTS), then dorsal raphe nucleus (DRN), where activated serotoninergic neurons increase brain serotonin, alleviating migraine.
Biying Liu, Chengya Huang, Xin Li, Haonan Yu, Yuefeng Xia, Kun Liu, Xingji You, Jingxiang Wu   +7 more
wiley   +1 more source

Survival, safety and belonging: An ethnographic study of experiences and perceptions of people who inject drugs accessing a supervised injecting Centre

Australian Journal of Social Issues, Volume 57, Issue 4, Page 829-846, December 2022., 2022
Abstract Introduction The inclusion of people who use drugs in the design and evaluation of their health services remains a relatively new phenomenon. The aim of the research was to explore the experiences and perceptions of people accessing the Medical Supervised Injecting Centre (MSIC), and Clinic 180, Sydney Australia, and the factors facilitating ...
Greg Rickard, Bethne Hart
wiley   +1 more source

Development of Grip self-help: An online patient-tailored self-help intervention for functional somatic symptoms in primary care

Internet Interventions, 2020
Functional Somatic Symptoms (FSS) are somatic symptoms for which no somatic cause can be identified despite adequate diagnostic testing. FSS are common, costly, and disabling, and treatment options are limited.Psychotherapy is one of few evidence-based ...
Judith G.M. Rosmalen, Anne van Gils, M. Angélica Acevedo Mesa, Robert A. Schoevers, Rei Monden, Denise J.C. Hanssen   +5 more
doaj  

Searching for the optimal number of response alternatives for the distress scale of the four-dimensional symptom questionnaire

BMC Psychiatry, 2019
Background The Four-Dimensional Symptom Questionnaire (4DSQ) is a self-report questionnaire designed to measure distress, depression, anxiety, and somatization. Prior to computing scale scores from the item scores, the three highest response alternatives
Jan van Bebber, Johanna T. W. Wigman, Rob R Meijer, Berend Terluin, Sjoerd Sytema, Lex Wunderink   +5 more
doaj   +1 more source