Results 131 to 140 of about 1,893,151 (298)

Children’s Hospital Environment Design Based on AHP/QFD and Other Theoretical Models

Buildings
Spatial environmental factors can effectively alleviate children’s fear of the medical environment when they seek medical treatment. This study focuses on the special environmental space of a children’s hospital, thoroughly considering the emotional ...
Haohua Zheng, Lingying Liu, Qi Zhang, Yihan Wang, Yangyang Wei   +4 more
doaj   +1 more source

Social signals and algorithmic trading of Bitcoin

, 2015
The availability of data on digital traces is growing to unprecedented sizes, but inferring actionable knowledge from large-scale data is far from being trivial.
Garcia, David, Schweitzer, Frank
core   +1 more source

Nurr1 Orchestrates Claustrum Development and Functionality

Advanced Science, EarlyView.
Nurr1 (Nr4a2) is the master transcription factor to control claustrum morphogenesis and cell fate decision postmitotically by inhibiting intracellular G‐protein signaling. Nurr1 deficiency alters the transcriptomic profiles of subcortical claustral neurons into neocortical insular neurons, resulting in defected claustrum development, impaired axonal ...
Kuo Yan, Andrew G. Newman, Pauline Lange, Susanne Müller, Marco Foddis, Stefan Paul Koch, Philipp Böhm‐Sturm, Maron Mantwill, Carsten Finke, Penghui Deng, Melissa Long, Dietmar Schmitz, Victor Tarabykin   +12 more
wiley   +1 more source

Empathetic and Emotive Design Heuristics

The design of user interfaces and systems that promote positive emotional interaction and reaction from end users is becoming a critical area in the design of applications and systems for use by the general population. In this paper we describe our work in the creation of a set of empathetic design heuristics that were developed from examination of the
Borycki, Elizabeth M., Kletke, Ryan, le Nobel, Claire, McWilliams, Georgia, Whitehouse, Sandy, Kushniruk, Andre W.   +5 more
openaire   +2 more sources

Design as a means of exploring the emotional component of scent [PDF]

, 2006
This paper demonstrates how industrial designers can generate engaging solutions by applying new technology to the area of scent-delivery through the use of practice-based research.
Hughes, Ben, Tillotson, Jenny
core  

XIAP Stabilizes DDRGK1 to Promote ER‐Phagy and Protects Against Noise‐Induced Hearing Loss

Advanced Science, EarlyView.
Mechanism of GAS‐mediated protection against noise‐induced hearing loss (NIHL). Noise exposure activates the ATF4/eIF2α axis, downregulating XIAP and promoting DDRGK1 degradation, thereby inhibiting ER‐phagy and leading to hair cell (HC) death. GAS treatment rescues XIAP and DDRGK1 expression, reactivating ER‐phagy to mitigate HC loss, synaptic damage,
Lin Yan, Yuhua Zhang, Jiawei Du, Yongjun Zhu, Wei Cao, Yongjie Wei, Han Wu, Shiyu Qiu, Shiyi Pan, Lian Chen, Pingping Liang, Renjie Chai, Jianming Yang, Qiaojun Fang   +13 more
wiley   +1 more source

Evaluation on AI-Generative Emotional Design Approach for Urban Vitality Spaces: A LoRA-Driven Framework and Empirical Research

Land
Recent advancements in urban vitality space design reflect increasing academic attention to emotional experience dimensions, paralleled by the emergence of AI-based generative technology as a transformative tool for systematically exploring the emotional
Ruoshi Zhang, Xiaoqing Tang, Lifang Wu, Yuchen Wang, Xiaojing He, Mengjie Liu   +5 more
doaj   +1 more source

Adenylyl Cyclase 8 in Dorsal CA1 Neurons Prevents Depressive‐Like Behaviors by Maintaining Neuronal Excitability and Glutamatergic Neurotransmission Through TIP39‐PTH2R Signaling

Advanced Science, EarlyView.
Depression, a prevalent neuropsychiatric disorder with unclear pathogenesis, involves dysfunctional adenylyl cyclase 8 (Adcy8) as a key risk factor. Chronic stress selectively reduces Adcy8 expression in the dorsal CA1 (dCA1) neurons. Depletion of Adcy8 in dCA1 excitatory neurons induces depressive‐like behaviors by impairing neuronal excitability and ...
Zi‐Jie Liu, Jia‐Rui Bi, Zong‐Yan Yu, Meng Tian, Zhi‐Yue Chen, Ran Wei, Miao‐Miao Wang, Hai‐Wei Zha, Yu‐Qing Zhang, Hong‐Jing Wang, Bang‐You Qiang, Shuang‐Shuang Sun, Xiao‐Juan Zhu, Wen‐Bing Chen, Dong Sun   +14 more
wiley   +1 more source

Emotional design of traditional Chinese cultural creative products based on user demand

Journal of Graphic Engineering and Design
Mortice-tenons are the main structural forms of ancient buildings, furniture, and woodwork in China. They are the inheritance of China's craft and cultural spirit, follow the principles of mechanics and have strong practicability.
Li Guangzhou, Ratthai Porncharoen
doaj   +1 more source

Navigating the Ethereal Tightrope: The Nanogenerator Manipulates Neurons for Immune Equilibrium

Advanced Science, EarlyView.
This review explores how nanogenerators modulate neuroimmune responses, offering innovative strategies for treating neurological disorders. By interfacing with neural pathways, they enable precise control of immune activity, especially via vagus nerve stimulation.
Jia Du, Rui Deng, Ya Wu, Hong‐Xia Ren, Zong‐Hong Lin, Yang‐Bao Miao   +5 more
wiley   +1 more source