Results 131 to 140 of about 1,902,736 (298)

Food as Experience A Design and Evaluation Methodology [PDF]

, 2009
This research, conducted for Frito Lay-North America, Inc, demonstrates how new product designs, package designs, concepts, and prototypes can be created based on the social, emotional, cognitive, and sensory information gathered through a combined ...
Baer, Roger, Kang, Sunghyun, Ladjahasan, Nora, Satterfield, Debra   +3 more
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A Non‐Mitophagy Activity of BNIP3L/NIX in Amygdala Glutamatergic Neurons is Essential for Contextual Fear Memory Formation

Advanced Science, EarlyView.
Contextual fear conditioning induces BNIP3L‐dependent mitochondrial fission in glutamatergic neurons of the BLA, independently of mitophagy. Loss of BNIP3L elevates Drp1Ser637 phosphorylation, thereby suppressing mitochondrial fission, compromising ATP production, and attenuating excitatory synaptic transmission.
Xingxian Zhang, Xinlei Mo, Xinyu Zhou, Xiaoliang Liu, Guizhi Li, Songhui Hu, Yangyang Lu, Chenze Zhu, Jinxi Feng, Zhitong Chen, Weiwei Hu, Yihui Cui, Zhong Chen, Xiangnan Zhang   +13 more
wiley   +1 more source

4‐Hydroxybenzyl Alcohol Mitigates Hyperlipidemia‐Associated Depression by Inhibiting Neuroinflammation via the NKIRAS2/NF‐κB Pathway

Advanced Science, EarlyView.
4‐HBA upregulates NKIRAS2 levels, inhibiting the activation of the NF‐κB pathway and subsequently reducing the levels of neuroinflammatory markers. This modulation helps restore normal mood and behavior in hyperlipidemic conditions, providing a potential therapeutic strategy for managing hyperlipidemia‐associated depression.
Ying Zhang, Meng Teng, Wenxuan He, Lanzhou Li, Yongfeng Zhang, Shimiao Wang, Chunyue Wang, Di Wang   +7 more
wiley   +1 more source

Evaluation on AI-Generative Emotional Design Approach for Urban Vitality Spaces: A LoRA-Driven Framework and Empirical Research

Land
Recent advancements in urban vitality space design reflect increasing academic attention to emotional experience dimensions, paralleled by the emergence of AI-based generative technology as a transformative tool for systematically exploring the emotional
Ruoshi Zhang, Xiaoqing Tang, Lifang Wu, Yuchen Wang, Xiaojing He, Mengjie Liu   +5 more
doaj   +1 more source

Empathetic and Emotive Design Heuristics

The design of user interfaces and systems that promote positive emotional interaction and reaction from end users is becoming a critical area in the design of applications and systems for use by the general population. In this paper we describe our work in the creation of a set of empathetic design heuristics that were developed from examination of the
Borycki, Elizabeth M., Kletke, Ryan, le Nobel, Claire, McWilliams, Georgia, Whitehouse, Sandy, Kushniruk, Andre W.   +5 more
openaire   +2 more sources

Recent Advances and Perspectives on Field‐Effect Transistors for Artificial Visual Neuromorphic Systems

Advanced Science, EarlyView.
This review presents a comprehensive overview of FET‐based visual neuromorphic systems, covering their semiconductor materials, core device architectures, and operating mechanisms. It further reviews their implementation in emulating biological visual functions, addresses current technological challenges, and outlines future development directions. The
Liu Yaqian, Lang Menghua, Xu Yihang, Zhang Manyu, Lei Chunkang, Lu Xiaozhou, Dou Yi, Wang Lingli, Jiang Liying, Hu Yuanyuan, Chen Huipeng, Jiang Lang   +11 more
wiley   +1 more source

Emotional design of traditional Chinese cultural creative products based on user demand

Journal of Graphic Engineering and Design
Mortice-tenons are the main structural forms of ancient buildings, furniture, and woodwork in China. They are the inheritance of China's craft and cultural spirit, follow the principles of mechanics and have strong practicability.
Li Guangzhou, Ratthai Porncharoen
doaj   +1 more source

ACSL1‐Dependent Microglial Lipoimmunometabolic Reprogramming Underlies Cognitive Deficits in Alcohol Use Disorder

Advanced Science, EarlyView.
This study reveals that chronic alcohol exposure selectively upregulates ACSL1 expression in prefrontal cortical microglia, driving lipid metabolism reprogramming and lipid droplet accumulation, which activates the NLRP3 inflammasome and sustains neuroinflammation. To reverse this process, a dual‐targeted lipid nanoparticle, siACSL1@LNP‐MR, is designed
Liang Hao, Xing‐Rui Cao, Bai‐Qiang Li, Fu‐Ying Zhao, Jia‐Mei Wang, Rui‐Kang Gao, Zhi‐Peng Cao, Zhen‐Xian Du, Hua‐Qin Wang   +8 more
wiley   +1 more source

Toward Emotional Design Feature Evaluation in Craft Development: Understanding the Top-Selling Chinese and Japanese Ceramic Teapots

IEEE Access
Crafts are products with both functional and aesthetic properties. Through emotional design, we can enhance not only the functionality of craft products but also their aesthetic appeal.
Xianghui Li, Takaya Yuizono, Van-Nam Huynh, Ruixuan Li   +3 more
doaj   +1 more source

Integration of psychological models in the design of artificial creatures [PDF]

, 2004
Artificial creatures form an increasingly important component of interactive computer games. Examples of such creatures exist which can interact with each other and the game player and learn from their experiences.
Bryant, Catherine M., Jones, Gareth J.F., Wills, A. J.   +2 more
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