Results 51 to 60 of about 73,117 (266)

Changes in emotional dysregulation profile among offspring of parents with bipolar disorder: a family-based intervention pilot study

International Journal of Bipolar Disorders
Offspring of parents with bipolar disorder (OBD) are at increased risk for mood and behavioral disorders, with emotional dysregulation being an early marker.
Erica Fongaro, Florence Pupier, Marie-Christine Picot, Nathalie Franc, Marion Soler, Emilie Olié, Virginie Maurice, Diane Purper-Ouakil, Hala Kerbage   +8 more
doaj   +1 more source

Clinical characterization of coexisting ADHD symptoms in a sample of adults with cyclothymia: A preliminary observational study

Journal of Affective Disorders Reports
Background: Cyclothymia seems to be often associated with coexisting ADHD symptoms, although this comorbidity is understudied. Emotional dysregulation is a core symptom of both conditions.
Margherita Barbuti, Ugo De Rosa, Martina Moriconi, Daria Bartolini, Elisa Schiavi, Giulio Perugi   +5 more
doaj   +1 more source

Food addiction and binge eating disorder are linked to shared and unique deficits in emotion regulation among female seeking bariatric surgery

Journal of Eating Disorders, 2023
Background Problematic eating behaviors can indicate obesity-related problems. Food addiction (FA) is not classified as an official diagnosis. However, given the many commonalities between FA and binge-eating disorder (BED) within the context of obesity,
Shahrzad Ahmadkaraji, Hojjatollah Farahani, Koosha Orfi, Fahimeh Fathali Lavasani   +3 more
doaj   +1 more source

CausalCellInfer: Prioritizing Cell‐Type‐Specific Disease Associations From Genetically Predicted Transcriptomes in Biobank Cohorts

Advanced Science, EarlyView.
Bulk and genotype‐imputed transcriptomes obscure the cellular drivers of complex disease. CausalCellInfer resolves them by integrating invariant marker selection, deep learning deconvolution, and regularized matrix completion. Applied to ∼500 000 UK Biobank participants across 29 traits, it uncovers hallmark cell‐type proportion shifts, including ...
Liangying Yin, Yujia Shi, Ruoyu Zhang, Yong Xiang, Jinghong Qiu, Pak‐Chung Sham, Hon‐Cheong So   +6 more
wiley   +1 more source

Executive function and clinical characteristics in children with attention-deficit hyperactivity disorder and emotional dysregulation

Sichuan jingshen weisheng
BackgroundComorbid attention-deficit/hyperactivity disorder （ADHD） and emotional dysregulation may represent a distinct subtype of ADHD， which is characterized by an increased risk of anxiety or depressive disorder and a poor clinical prognosis， so ...
Yang Yanping, Li Sixun, Wang Meiwen, Wang Zhuo, Liu Pei, Luo Tingting, Tao Yujie, Huang Yi   +7 more
doaj   +1 more source

Sub‐Second Ratiometric Fluorescence Imaging of Histamine Dynamics in Living Cells via a Supramolecular Probe

Advanced Science, EarlyView.
A tailored tripartite supramolecular ratiometric probe, engineered by modulating the fluorogenic guest's cationic locus, enables ultrafast histamine monitoring in living cells. Utilizing a competitive displacement mechanism, this system achieves a sub‐second response time with high selectivity.
Chenming Chan, Yujie Han, Yu‐Fei Song, Chunlei Jiang, Qi‐Wei Zhang   +4 more
wiley   +1 more source

Overlaps and differences in the core symptoms of patients with attention-deficit/hyperactivity disorder and patients with borderline personality disorder

Frontiers in Psychiatry
BackgroundIndividuals with attention-deficit/hyperactivity disorder (ADHD) and individuals with borderline personality disorder (BPD) show symptomatic overlaps.
Anna Christen, Anna Christen, Marialuisa Cavelti, Rolf-Dieter Stieglitz, Rolf-Dieter Stieglitz, Beatrice Abt-Mörstedt, Hannes Bitto, Patricia E. Newark, Franz Moggi, Kerstin Gabriel Felleiter, Niklaus Stulz, Andreas Riedel, Salvatore Corbisiero, Salvatore Corbisiero   +13 more
doaj   +1 more source

Stakeholder Perspectives on Therapeutic and Safe Building Design in Residential Care

Australian Journal of Social Issues, EarlyView.
ABSTRACT Residential care is a form of out‐of‐home care that plays a critical role in supporting vulnerable young people in Australia. However, there is an evidence gap regarding the built environment in this context. This research aimed to explore the perspectives of key stakeholders in residential care in Victoria, Australia, regarding design that ...
Carmen Schroder, Olivia Crivari, Phillippa Carnemolla, Libby Callaway   +3 more
wiley   +1 more source

Baihe Zhimu Decoction ameliorates anxious depression via PI3K/AKT/mTOR pathway‐mediated neuroprotection and inhibition of hippocampal neuronal apoptosis

Animal Models and Experimental Medicine, EarlyView.
Baihe Zhimu Decoction alleviates anxious depression‐like behaviors and protects hippocampal neurons. Chemical profiling and network pharmacology reveal multiple active components acting via the PI3K/AKT/mTOR pathway, enhancing neuronal survival and function, as confirmed by multi‐level in vitro and in vivo validation.
Yuanshan Han, Kexin He, Haolan Yang, Jiacheng Dai, Ronglin Chen, Yang Liu, Yuhong Wang, Lin Tang, Hongqing Zhao   +8 more
wiley   +1 more source

A Mouse Model of Depression‐Tumor Multimorbidity Reveals the Mechanism of Tumor Growth Accelerated by Depression

Animal Research and One Health, EarlyView.
Depression accelerates tumor growth by dysregulation of tumor immune microenvironment. (A) Modeling methods: Subcutaneous tumor models were established under chronic unpredictable mild stress conditions, including cold swimming, physical restraint, and food/water deprivation, leading to increased tumor growth.
Yakun Ren, Xinpei Wang, Wen Wang, Xingjiu Yang, Mengyuan Li, Jing Du, Ran Gao   +6 more
wiley   +1 more source