Results 211 to 220 of about 208,432 (313)

Treatment Continuation and Long‐Term Outcomes of Perampanel in Primary Orthostatic Tremor; A Cohort Study

open access: yesMovement Disorders Clinical Practice, EarlyView.
Background Primary orthostatic tremor (POT) is a rare hyperkinetic movement disorder with limited and largely ineffective treatment options. Perampanel has been suggested as a therapy, but has so far only been investigated in small studies with short duration.
Wietske A. Babeliowsky   +4 more
wiley   +1 more source

Professionalization as a Factor of Heterogeneity in Family and Nonfamily Firms: Effects on Performance

open access: yesManagerial and Decision Economics, EarlyView.
ABSTRACT This study examines the relationship between firm ownership and organizational performance with a focus on heterogeneity in the professionalization of management. Using a comprehensive panel dataset of Spanish manufacturing firms, the study identifies significant ownership‐ and management model‐related differences in productive efficiency. The
Javier Ortiz, Ana F. Gargallo‐Castel
wiley   +1 more source

Multi‐Targeting Ligands as Prospective Therapeutics for Alzheimer's Disease, a Prevalent Neurodegenerative Disorder: Mechanistic Insights, Emerging Targets and Drug Discovery Campaigns

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Alzheimer's disease (AD) is a debilitating neurodegenerative condition characterized by progressive cognitive impairment, memory deterioration, and neuronal dysfunction. Its complex pathophysiology involves multiple interlinked processes, including amyloid‐β (Aβ) aggregation, tau hyperphosphorylation, oxidative stress, neuroinflammation ...
Amandeep Thakur   +6 more
wiley   +1 more source

Clinician insights into pediatric temporary feeding tube management: Unseen barriers, unclear roles revealed from a prospective mixed methods study

open access: yesNutrition in Clinical Practice, EarlyView.
Abstract Background Temporary feeding tubes are common in pediatric healthcare, but research on understanding how clinicians manage their use and understand the impact on families is limited. Existing research often overlooks clinician perspectives despite tensions between clinical priorities and family needs. This study aimed to understand clinicians'
Claire Reilly   +4 more
wiley   +1 more source

Exploring the disease burden and quality of life in patients with short bowel syndrome with intestinal failure: Insights from exit interviews in the glepaglutide EASE SBS‐1 phase 3 trial

open access: yesNutrition in Clinical Practice, EarlyView.
Abstract Background A randomized, double‐blind, placebo‐controlled trial was conducted to evaluate efficacy and safety of glepaglutide in patients who have short bowel syndrome with intestinal failure (SBS‐IF). At the end of the trial, exit interviews were conducted to explore participants' experiences and to assess the impact of the disease and ...
David F. Mercer   +5 more
wiley   +1 more source

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