Results 91 to 100 of about 1,401,274 (259)
Collateral and Debt Maturity Choice. A Signaling Model [PDF]
, 2005 This paper derives optimal loan policies under asymmetric information where banks offer loan contracts of long and short duration, backed or unbacked with collateral. The main novelty of the paper is that it analyzes a setting in which high quality firms
Tra, Pham Thi Thu,, Lensink, Robert,
core +1 more source
VlPAG/DRN Microglia Drive Neuropathic Pain‐Induced Depression via a Defined Neuroimmune Axis
Advanced Science, EarlyView.Peripheral nerve injury (SNI) induces neuropathic pain, activates midbrain microglia, and triggers an NLRP3–IL‐1β–dependent inflammatory cascade. IL‐1β signals through IL‐1R1 on vlPAG/DRN VGLUT2+ neurons (vlPAG/DRNGlu), inducing hyperexcitability and driving the vlPAG/DRNGlu→BNSTGABA circuit to produce the affective component of neuropathic pain ...
Jing Yang +7 more
wiley +1 more source
The Effect of Acceptance and Commitment Group Therapy on Emotional Maturity in Female Adolescents With Visual Impairment [PDF]
Journal of RehabilitationObjective Adolescents with visual impairments have less opportunity to adapt emotionally to the environment and, as a result, experience more social and academic problems.
Fatemeh Mirmohammadi +1 more
doaj
Debt maturity, risk, and asymmetric information [PDF]
We test the implications of Flannery’s (1986) and Diamond’s (1991) models concerning the effects of risk and asymmetric information in determining debt maturity, and we examine the overall importance of informational asymmetries in debt maturity choices.
Marco A. Espinosa-Vega +3 more
core
Developmental and gender trends in emotional literacy and interpersonal competence among Japanese children [PDF]
, 2015 This study explored cross-sectional gender and grade level trends in emotional literacy and interpersonal competence among 913 elementary and middle school students in Japan.
Saeki, Elina +5 more
core +1 more source
Advanced Science, EarlyView.Androgenetic alopecia (AGA) is a common form of hair loss with limited treatment options. Silencing of WNT5A signaling, which is widely known as the trigger of the ncWNT signaling pathway, happens in hair follicle stem cells from balding areas. It leads to downregulation of ATF3 and its target FOSB.
Ruiyu Luo +10 more
wiley +1 more source
Advanced Science, EarlyView.A novel dual‐organelle proximity labeling platform, DuO‐SCOUT, decodes the complex landscape of systemic organ‐organ communication by capturing both classical and unconventional secretomes. Application in metabolic models maps the adipose‐to‐brain secretory relay, identifying selective extra‐hypothalamic sites for adipose‐derived factors and expanding ...
Fenglian Yang +7 more
wiley +1 more source
Higher capability maturity dynamics of UK construction organisations [PDF]
This paper attempts to identify the dynamics of the CMM (Capability Maturity Model) higher capability maturity level characteristics within the UK construction context from a theoretical perspective.
Amaratunga, Dilanthi +2 more
core +3 more sources
Perceived emotional intelligence as a predictor of depressive symptoms after a one year follow-up during adolescence [PDF]
, 2016 Research to date has identified various risk factors in the emergence of depressive disorders in adolescence. There are very few studies, however, which have analyzed the role of perceived emotional intelligence in depressive symptoms longitudinally ...
Susana Paino +6 more
core +1 more source
Advanced Science, EarlyView.MethyAnno enables robust and interpretable annotation of single‐cell DNA methylation data by integrating multi‐scale epigenetic information, bidirectional cross‐attention, and prototype‐based metric learning. The framework resolves rare and novel cell types across datasets while revealing cell‐type‐specific epigenetic signatures associated with disease
Yuhang Jia +4 more
wiley +1 more source