Results 141 to 150 of about 4,539,228 (388)

Nurr1 Orchestrates Claustrum Development and Functionality

Advanced Science, EarlyView.
Nurr1 (Nr4a2) is the master transcription factor to control claustrum morphogenesis and cell fate decision postmitotically by inhibiting intracellular G‐protein signaling. Nurr1 deficiency alters the transcriptomic profiles of subcortical claustral neurons into neocortical insular neurons, resulting in defected claustrum development, impaired axonal ...
Kuo Yan, Andrew G. Newman, Pauline Lange, Susanne Müller, Marco Foddis, Stefan Paul Koch, Philipp Böhm‐Sturm, Maron Mantwill, Carsten Finke, Penghui Deng, Melissa Long, Dietmar Schmitz, Victor Tarabykin   +12 more
wiley   +1 more source

Relationships between gross motor skills, psychological resilience, executive function, and emotional regulation among Chinese rural preschoolers: A moderated mediation model

Heliyon
Background: Emotional regulation is a critical component of emotional intelligence, particularly during the preschool stage, a key period for children's development.
Xinyue Ma, Ning Yang, Meixian Huang, Shuwei Zhan, Houwen Cao, Shan Jiang   +5 more
doaj   +1 more source

Discovery of a Novel and Potent Kir4.1 Inhibitor as a Safe and Rapid‐Onset Antidepressant Agent in Mice

Advanced Science, EarlyView.
The preferred derivative JX3212 demonstrates strong inhibitory activity against Kir4.1 with favorable druggability and shows significant antidepressant efficacy in vivo. Abstract Major depressive disorder is a serious psychiatric disorder for which novel and fast‐acting antidepressants are required.
Sisi Wang, Xiaoyu Zhou, Mengdan Li, Chao Zhang, Haiyan Xu, Jingyi He, Li Zhan, Yueling Gu, Hao Gu, Tianyu Tu, Hanfang Liu, Taotao Lu, Yueming Zheng, Jian Li, Zhaobing Gao, Yixiang Xu   +15 more
wiley   +1 more source

Social competence and emotional regulation in preschool children as a function of maternal acceptance and rejection

, 2021
Dilan Bayındır, Gülçin Güven, Türker Sezer, Ezgi Akşin, Elif Yılmaz   +4 more
openalex   +1 more source

The relationship between difficulties in emotion regulation and dysfunctional technology use among adolescents [PDF]

, 2019
Objectives Since two decades scientific research is studying excessive and dysfunctional new technologies use and its influences on people’s lives, in terms of personal, relational, scholastic and work functioning impairment.
Amendola, Simone, Cerutti, Rita, Guidetti, Vincenzo, Spensieri, Valentina   +3 more
core  

Gender influences on emotional self-regulation among Malaysian academicians [PDF]

, 2010
The Malaysian government aspires to become a leading international education hub, and inline with the aspiration, the Ministry of Higher Education introduced the key performance indicators for the academicians.
Alias, Rose Alinda, Haron, Haryani, Syed Mustafa, Sharifah Muzlia   +2 more
core   +1 more source

Astrocytic PERK Deficiency Drives Prefrontal Circuit Dysfunction and Depressive‐Like Behaviors

Advanced Science, EarlyView.
Chen et al. show that the endoplasmic reticulum (ER) stress sensor PERK is downregulated in prefrontal cortex (PFC) astrocytes in major depressive disorder and in chronic‐stress mouse models. In young mice, astrocyte‐specific PERK loss reduces the synaptogenic cue thrombospondin‐1 (TSP1), leading to synaptic and circuit deficits and depressive‐like ...
Kai Chen, Riya Gupta, Yosuke M. Morizawa, Yu Qin, Xingyu Du, Cynthia Pang, Osama Al‐Dalahmah, Maura B. Dupont, Guang Yang   +8 more
wiley   +1 more source

Fluctuation of cognitive-emotional states during competition:an idiographic account [PDF]

, 2007
The purpose of this paper is to describe athletes’ cognitive-emotional processes during competitions through an idiographic and ecologically valid study method based on verbal protocols and event sequential analyses.
Calmeiro, Luis, Tenenbaum, Gershon
core  

XIAP Stabilizes DDRGK1 to Promote ER‐Phagy and Protects Against Noise‐Induced Hearing Loss

Advanced Science, EarlyView.
Mechanism of GAS‐mediated protection against noise‐induced hearing loss (NIHL). Noise exposure activates the ATF4/eIF2α axis, downregulating XIAP and promoting DDRGK1 degradation, thereby inhibiting ER‐phagy and leading to hair cell (HC) death. GAS treatment rescues XIAP and DDRGK1 expression, reactivating ER‐phagy to mitigate HC loss, synaptic damage,
Lin Yan, Yuhua Zhang, Jiawei Du, Yongjun Zhu, Wei Cao, Yongjie Wei, Han Wu, Shiyu Qiu, Shiyi Pan, Lian Chen, Pingping Liang, Renjie Chai, Jianming Yang, Qiaojun Fang   +13 more
wiley   +1 more source

Examining the Relationship Between Emotional Regulation and Academic Grit among High-Achieving University Students

Educational Process: International Journal
Background/purpose. Emotional regulation and academic grit significantly influence students' academic success. This study aimed to examine the relationship between emotional regulation and academic grit among high-achieving university students ...
Eslam Elsayed Abdelshafy, Sara Asem Reiyad, Hussam Khalifa Aldawsari, Mamdouh Mosaad Helali   +3 more
doaj   +1 more source