Results 101 to 110 of about 3,811 (247)

Shared and Distinctive Ultrastructural Abnormalities Expressed by Megakaryocytes in Bone Marrow and Spleen From Patients With Myelofibrosis [PDF]

, 2020
Numerous studies have documented ultrastructural abnormalities in malignant megakaryocytes from bone marrow (BM) of myelofibrosis patients but the morphology of these cells in spleen, an important extramedullary site in this disease, was not investigated
Barosi G., Genova M.L., Guglielmelli P., Mazzarini M., Migliaccio A.R., Rosti V., Vannucchi A.M., Zingariello M.   +7 more
core   +1 more source

Common progenitor origin for Rosai–Dorfman disease and clear cell sarcoma

The Journal of Pathology, Volume 264, Issue 3, Page 243-249, November 2024.
Abstract Histiocytic neoplasms (HNs) in adults have been reported to be associated with a high prevalence of coexisting haematological and solid malignancies. While a proportion of coexisting HNs and haematological malignancies share identical genetic alterations, the genetic association between HNs and solid malignancies has scarcely been reported. We
Aki Sato, Nozomi Yusa, Hiroyuki Takamori, Eigo Shimizu, Kazuaki Yokoyama, Satoshi Ichikawa, Hisayuki Yokoyama, Yuki Kasahara, Kodai Enda, Fumiyoshi Fujishima, Ryo Ichinohasama, Yasunori Ota, Seiya Imoto, Yasuhito Nannya   +13 more
wiley   +1 more source

A Rare Case of Primary Intraparenchymal Rosai‐Dorfman Disease

iRADIOLOGY, EarlyView.
Lin Chen, Rui Zhou
wiley   +1 more source

Severe acute liver disease in adults: Contemporary role of histopathology

Histopathology, Volume 85, Issue 4, Page 549-561, October 2024.
This overview provides an insight into the contemporary role of biopsies (as well as explant and autopsy material) in diagnosing acute liver disease. It outlines up‐to‐date clinical definitions of liver injury and considers recent recommendations for the diagnosis of AIH and drug‐induced, autoimmune‐like hepatitis (DI‐AIH).
Andrew D Clouston, Annette S H Gouw, Dina Tiniakos, Pierre Bedossa, Elizabeth M Brunt, Francesco Callea, Hans‐Peter Dienes, Zachary D Goodman, Stefan G Hubscher, Sanjay Kakar, David E Kleiner, Carolin Lackner, Young N Park, Eve A Roberts, Peter Schirmacher, Luigi Terracciano, Michael Torbenson, Ian R Wanless, Yoh Zen, Alastair D Burt   +19 more
wiley   +1 more source

When Mechanical Stress Matters: Generation of Polyploid Giant Cancer Cells in Tumor‐Like Microcapsules

Advanced Functional Materials, Volume 34, Issue 35, August 28, 2024.
Herein, the emergence of tumor heterogeneity and, in particular, Polyploid Giant Cancer Cells is analyzed, as a product of mechanical stress. Assays are carried out with MCF7 cancer cells, cultured on Flasks, spheroids, and three‐dimensional tumor‐like microcapsules.
Yasmin Antonelli, René Krüger, Adrian Buehler, Mahshid Monavari, Miguel Fuentes‐Chandía, Federico Colombo, Ralf Palmisano, Anja K. Boßerhoff, Melanie Kappelmann‐Fenzl, Johannes Schödel, Aldo R. Boccaccini, Christine Selhuber‐Unkel, Gaelle Letort, Aldo Leal‐Egaña   +13 more
wiley   +1 more source

Rosai-Dorfman disease of vertebra: Case report and literature review

The Turkish Journal of Pediatrics, 2016
Rosai-Dorfman disease is a rare benign histiocytic disorder that arises predominantly in lymph nodes with fever and malaise, but can affect various organs, with or without lymphadenopathy.
Zoran Igrutinovic, Rasa Medovic, Slavica Markovic, Gordana Kostic, Zorica Raskovic, Jelena Tanaskovic-Nestorovic, Marija Radovanovic, Biljana Vuletic   +7 more
doaj   +1 more source

Astaxanthin Alleviates Autoimmune Hepatitis by Modulating CD8+ T Cells: Insights From Mass Cytometry and Single‐Cell RNA Sequencing Analyses

Advanced Science, Volume 11, Issue 30, August 14, 2024.
This study revealed that astaxanthin (ASX) treatment effectively alleviated autoimmune hepatitis (AIH) in mice induced by concanavalin A (ConA). Through mass cytometry and single‐cell RNA sequencing, this study deciphered the heterogeneous CD8+ T cells profile of AIH liver immune microenvironment regulated by ASX, providing novel insights for the ...
Yuting He, Mingjie Ding, Jiakai Zhang, Changjun Huang, Jihua Shi, Yun Wang, Ruolin Tao, Zeyu Wu, Wenzhi Guo   +8 more
wiley   +1 more source

CD14+ Dendritic‐Shaped Cells Functioning as Dendritic Cells in Rheumatoid Arthritis Synovial Tissues

ACR Open Rheumatology, Volume 6, Issue 7, Page 412-420, July 2024.
Objective We previously reported that CD14+ dendritic‐shaped cells exhibit a dendritic morphology, engage in pseudo‐emperipolesis with lymphocytes, and express CD90 in the perivascular areas of rheumatoid arthritis (RA) synovial tissues. However, it remains unclear whether these CD14highCD90intermediate(int) cells function as dendritic cells.
Rie Kurose, Takashi Satoh, Akira Kurose, Yasuyuki Ishibashi, Miwa Uzuki, Yuji Wakai, Tomoyuki Sasaki, Kinji Ishida, Katsutoshi Ogasawara, Takashi Sawai   +9 more
wiley   +1 more source

Mixed histiocytic neoplasms: A multicentre series revealing diverse somatic mutations and responses to targeted therapy

British Journal of Haematology, Volume 205, Issue 1, Page 127-137, July 2024.
Novel somatic mutations were identified in mixed histiocytic neoplasms, including KRAS, MAP2K2, MAPK3, non‐V600‐BRAF, RAF1 and BICD2‐BRAF fusion. Targeted treatment was more likely to result in complete response and compared to other treatment modalities. Summary Histiocytic neoplasms are diverse clonal haematopoietic disorders, and clinical disease is
Joshua S. Friedman, Benjamin H. Durham, Anne S. Reiner, Mariko Yabe, Kseniya Petrova‐Drus, Ahmet Dogan, Melissa Pulitzer, Klaus J. Busam, Jasmine H. Francis, Raajit K. Rampal, Gary A. Ulaner, Ryan Reddy, Randy Yeh, Vaios Hatzoglou, Mario E. Lacouture, Veronica Rotemberg, Roei D. Mazor, Oshrat Hershkovitz‐Rokah, Ofer Shpilberg, Gaurav Goyal, Ronald S. Go, Jithma P. Abeykoon, Karen Rech, Diana Morlote, Shiraz Fidai, Vedavyas Gannamani, Maryam Zia, Omar Abdel‐Wahab, Katherine S. Panageas, Marc K. Rosenblum, Eli L. Diamond   +30 more
wiley   +1 more source

Rosai Dorfman disease- A rare entity: Case report in North Indian male

Asian Journal of Medical Sciences, 2014
Rosai Dorfman disease is a rare disease characterized by histiocytic proliferation of lymph node in young adults. We present here the case of a 67 years old Indian male presenting with lymphadenopathy and pyrexia of unknown origin for 16 months duration.
Ankur Baruah
doaj   +1 more source