Results 51 to 60 of about 2,806 (197)

Drug-induced liver injury [PDF]

, 2016
Drug-induced liver injury (DILI) remains the most common cause of acute liver failure (ALF) in the western world. Excluding paractamol overdose, nearly all DILI encountered in the clinical setting is idiosyncratic in nature, since affected individuals ...
A, Amacher, Chalasani, Chen, Chien, El Sherrif, Hillman, Maggi, Russo, Sakaan, Studniarz, Suk, Yeong   +12 more
core   +1 more source

Variable extent of emperipolesis in the evolution of Rosai Dorfman disease: Diagnostic and pathogenetic implications

Journal of Cytology, 2009
This study examines variation of morphologic features, including emperipolesis, during the evolution of a case of Rosai Dorfman Disease (RDD). A 44-year-old male patient with RDD affecting the salivary glands, cervical lymph nodes, nasal and maxillary ...
Iyer Venkateswaran, Handa Kumud, Sharma Mehar   +2 more
doaj  

Rosai-Dorfman Disease- A Surprise diagnosis in Follow up of SCC Pyriform Sinus -Post Surgery and CTRT [PDF]

National Journal of Laboratory Medicine, 2013
Rosai-Dorfman disease also known as Sinus Histiocytosis with massive Lymphadenopathy (SHML). SHML was first described by Rosai and Dorfman in 1969 [1] and is now considered a non malignant inflammatory disorder in which the precise origin of ...
Nandeesh M, Anitha T.K., Santosh R.
doaj   +1 more source

A rare case of purely cutaneous Rosai–Dorfman’s disease: Xanthoma-like presentation

Indian Journal of Dermatopathology and Diagnostic Dermatology, 2022
Rosai–Dorfman’s disease (RDD) is sinus histiocytosis with massive lymphadenopathy. Cutaneous RDD is a rare entity that presents with isolated skin involvement without any systemic involvement. We report a 35-year-old man with an asymptomatic large nodule
Sushanti Jadhav, Atul Dongre, Bhushan Darkase, Ameet Dandale   +3 more
doaj   +1 more source

Megakaryocyte emperipolesis in a child with chronic neutropenia: an unusual coexistence

The Turkish Journal of Pediatrics, 2001
The term emperipolesis defines the temporary presence of one cell within another's cytoplasm. In clinical use, megakaryocyte emperipolesis is the penetration of hematopoietic cells into the cytoplasm of megakaryocytes.
D Aslan, S Yetgin
doaj  

Rosai-Dorfman Disease: A Clinico-pathological Presentation of Three Cases and Review of Literature [PDF]

Journal of Clinical and Diagnostic Research, 2018
Rosai-Dorfman Disease (RDD) or Sinus Histiocytosis with Massive Lymphadenopathy (SHML) is a rare histiocytic disorder of unknown aetiology which presents as a benign, self-limiting disease of phagocytic histiocytes occurring mainly in the first and ...
Francis Ikechukwu Ukekwe, Uchechukwu Obiora Ezomike, Osita Uchenna Ezenwosu, Christopher Bismarck Eke, Chibueze Onyekachi Nwokoro   +4 more
doaj   +1 more source

Defective neutrophil clearance in JAK2V617F myeloproliferative neoplasms drives myelofibrosis via immune checkpoint CD24. [PDF]

Blood
Myeloproliferative neoplasms (MPNs) are hematopoietic stem cell-driven malignancies marked by excessive myelopoiesis and high risk of myelofibrosis, which remains therapeutically challenging. Senescent neutrophils home daily to the bone marrow (BM) to be
Khatib-Massalha E, Di Buduo CA, Chédeville AL, Ho YH, Zhu Y, Grockowiak E, Date Y, Khuat LT, Fang Z, Quesada-Salas J, Carrillo Félez E, Migliavacca M, Montero I, Pérez-Simón JA, Balduini A, Méndez-Ferrer S.   +15 more
europepmc   +3 more sources

Striking emperipolesis in megakaryocytes of gray platelet syndrome [PDF]

Blood, 2019
![Figure][1] An 11-year-old girl was diagnosed with gray platelet syndrome (GPS) with compound heterozygous NBEAL2 mutations after presenting with recurrent epistaxis and thrombocytopenia. Bone marrow examination was performed to evaluate for myelofibrosis.
Eric McGinnis, Kate M. Chipperfield
openaire   +2 more sources

Hyperammonemia-induced toxicity for the developing central nervous system [PDF]

, 2007
In pediatric patients, hyperammonemia can be caused by various acquired or inherited disorders such as urea cycle deficiencies or organic acidemias. The brain is much more susceptible to the deleterious effects of ammonium during development than in ...
Braissant, O., Cagnon, L.
core   +1 more source

Prognosis of pediatric‐onset inflammatory bowel disease associated with primary sclerosing cholangitis: A population‐based study

Journal of Pediatric Gastroenterology and Nutrition, Volume 81, Issue 5, Page 1180-1188, November 2025.
Abstract Objectives To assess whether the prognosis of pediatric‐onset inflammatory bowel disease (IBD) is influenced by its association with primary sclerosing cholangitis (PSC) considering medical treatment, bowel resection, risk of cancer, and mortality. Methods A retrospective population‐based study was conducted using data from the EPIMAD Registry,
Marie‐Laura Godet, Hélène Sarter, Frédéric Gottrand, Colin Saoudi, Alexandre Louvet, Mathurin Fumery, Guillaume Savoye, Ariane Leroyer, Corinne Gower‐Rousseau, Delphine Ley, Madeleine Aumar   +10 more
wiley   +1 more source