Results 121 to 130 of about 20,054 (263)

Estimating the Benefits of the Comprehensive Disease-modifying Pharmacological Treatment in Patients with Heart Failure. [PDF]

Card Fail Rev
Escobar C, Caravaca-Pérez P, Fernandez-Rodriguez JM, Gomez-Otero I, Lozano-Bahamonde A, Pérez-Cabeza AI, Pérez-Silvestre J, Rafols C, Saldaña-García J, Esteban-Fernández A.   +9 more
europepmc   +1 more source

Crossing Tuition Borders: Evaluating AB‐91 Through an Equity‐Minded Lens in California Community Colleges

New Directions for Community Colleges, EarlyView.
ABSTRACT California's Assembly Bill 91 (AB‐91), passed in 2023 and effective Fall 2024, authorizes nine community colleges in the San Diego and Imperial Counties region to waive nonresident tuition for low‐income Mexican national students residing within forty‐five miles of the U.S.‐Mexico border.
Jada S. Sims, Antonio Estrella Vega
wiley   +1 more source

Efficacy of SGLT2 inhibitors in patients recently hospitalized for heart failure: an exploratory prespecified pooled analysis of the DELIVER and EMPEROR-preserved trials. [PDF]

Front Cardiovasc Med
Xue X, Hu M, Chi J, Li J, Zhang W.
europepmc   +1 more source

Clinical Outcomes of the Allegra Transcatheter System in Bioprosthetic Aortic Valve Failure: A Multicentre Valve‐in‐Valve Registry

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Introduction The prevalence of bioprosthetic aortic valve failure is increasing due to the broader use of bioprosthetic valves, both surgical and transcatheter, and an ageing population. Registry data indicate a higher risk of coronary obstruction and elevated gradients following valve‐in‐valve transcatheter aortic valve implantation (TAVI ...
Hilal Khan, Mohamed Ali, Abdalazeem Ibrahem, Karim Ratib, Nur Ilia Mohd Zaki, Freidoon Keshavarzi, Alok Shah, Hesham Abdelaziz, Ayush Khurana, Alexander Chase, Diana A. Gorog, Rajiv Das, Azfar Zaman, Mohammad AlKhalil, Mohamed Farag   +14 more
wiley   +1 more source

Democritus: Homotopy-Localized Causal Discourse Extraction from Language. [PDF]

Entropy (Basel)
Mahadevan S.
europepmc   +1 more source

In Silico Clinical Trials in Drug Development: Virtual Patients, Applications, and Regulatory Convergence

Clinical Pharmacology &Therapeutics, EarlyView.
Conventional clinical trials remain the benchmark for evaluating therapeutic safety and efficacy, yet they are constrained by escalating costs, withdrawal over the extended follow‐up periods, recruitment difficulties, ethical limits, and a restricted ability to characterize heterogeneous populations.
Maximilian Balmus, Sheng‐Ya Wang, Edward W. G. Ashton, Rosie K. Barrows, Molly Monks, Yuzhang Ge, Arthur Lefebvre, Steven A. Niederer   +7 more
wiley   +1 more source

The Role of SGLT2 Inhibitors in the Prevention of Type 2 Diabetes: A Narrative Review of Current Evidence. [PDF]

Diabetes Ther
Owczarczyk-Durma AC, Blicharska M, Czupryniak L.   +2 more
europepmc   +1 more source

Toward the Use of Real‐World Data for Regulatory and HTA Decision‐Making: Experiences and Recommendations from Six EU‐Funded Projects

Clinical Pharmacology &Therapeutics, EarlyView.
Real‐world data are increasingly important for regulatory and health technology assessment decision‐making, yet their effective use across Europe remains limited by technical, methodological, regulatory, and societal challenges. Drawing on the experiences of six Horizon Europe projects in the MetReal cluster, this review summarizes common barriers and ...
Martin Russek, Jonas Peltner, Kerstin Pfeifer, Theodoros N. Arvanitis, Dirk De Valck, Sieta T. de Vries, Michel Dumontier, Vera Ehrenstein, Omaima El Hakouni, Gregory Epiphaniou, Gokhan Ertaylan, Joana Fernandes, Scott Hansen, Stuart Harrison, Erzsébet Horváth‐Puhó, Saif Ul Islam, Pekka Kahri, Julia K. Mader, Carsten Maple, Nikolaos Matragkas, Shivani Misra, Peter G.M. Mol, Anne Paakinaho, Sami Pakarinen, Martina Radanović, Evy Reviers, Kathrine Kold Sørensen, Marco Spruit, Christina Tikka, Anna‐Maija Tolppanen, Christian Torp‐Pedersen, Mirna Vela, Thuan Vo, Puriya Daniel Würtz Yazdanfard, Britta Haenisch   +34 more
wiley   +1 more source

Tirzepatide and SGLT2 Inhibitors for Heart Failure With Preserved Ejection Fraction and Obesity: Entering a New Cardiometabolic Therapeutic Era. [PDF]

Endocrinol Diabetes Metab
Mohamed ZI, Shidane AA, Abdiasis AM, Hussein MH, Ibrahim AO, Abdi AA, Hashi KI, Mohamud MA, Mohamed AJ.   +8 more
europepmc   +1 more source

Thresholds: The metaphorical foundations of powerful knowledge

The Curriculum Journal, EarlyView.
Abstract This paper advances a theoretical account of threshold concepts as metaphorical‐relational structures that reorganise meaning across contexts. Building on conceptual metaphor theory, we propose that threshold concepts can be understood as sites of schema‐level reorganisation: deep, embodied patterns of relational logic that scaffold abstract ...
Maria Karrol, Elizaveta Lyssova‐Golomzina   +1 more
wiley   +1 more source