Results 31 to 40 of about 2,298 (213)
α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates
FEBS Letters, EarlyView.Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino +2 more
wiley +1 more source
Sosyal Ekonomik Araştırmalar Dergisi, 2012 Bu araştırmanın amacı, özel güvenlik görevlilerinin kişilik özellikleri, empatik eğilim ve iletişim becerilerinin eğitim düzeyi ve görev şekli değişkenlerine göre anlamlı düzeyde farklılaşıp farklılaşmadığını belirlemek ve aralarındaki ilişkiyi ...
Ruhi Yiğit, M. Engin Deniz
doaj +4 more sources
The Post-Verbal Position of Non-Core Clause Elements in Persian [PDF]
̒Ilm-i ZabānPersian is a verb-final language; that is, its basic unmarked word order is SOV. Clauses in Persian, like other languages, have both the core- elements and non-core elements.
Hussein Piri +3 more
doaj +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Procedia - Social and Behavioral Sciences, 2009 AbstractThis study is carried out with experimental design with an aim to reveal effects of Communication with children course on preschool teacher trainees’ emphatic tendencies. The sample of the study is composed of 299 senior teacher trainees- whose average age is 23.13- at Child Development Education and Kindergarten Education at Faculty of ...
Arslan, Emel +2 more
openaire +2 more sources
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Türk Spor ve Egzersiz Dergisi, 2014 The research consists of a screening model aimed at evaluating the Emphatic Tendency Levels of elite university tennis players in terms of different variables.
Atilla Pulur, Ebru Karabulut
doaj
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source