Results 51 to 60 of about 66,268 (258)
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Türk Spor ve Egzersiz Dergisi, 2014 The research consists of a screening model aimed at evaluating the Emphatic Tendency Levels of elite university tennis players in terms of different variables.
Atilla Pulur, Ebru Karabulut
doaj
Stop Release in Polish English — Implications for Prosodic Constituency [PDF]
, 2014 Although there is little consensus on the relevance of non-contrastive allophonic processes in L2 speech acquisition, EFL pronunciation textbooks cover the suppression of stop release in coda position.
Anna Balas +40 more
core +3 more sources
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
MAINTAINING JAVANESE LANGUAGE AND CULTURE TO SUPPORT CHARACTER EDUCATION IN GLOBALIZATION ERA33 [PDF]
, 2012 In their daily life, Javanese society uses Javanese as a means of communication. However, because of the rapid development of communication and information technology and social needs to communicate in globalization era, Javanese societies tend to use
Ngadiso, Ngadiso
core
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Forum Ilmu Sosial, 2011 Most of drug abuse victims are included in young ages, which are, between 15 to 25 years old, withthe tendency of increasing number of victims from year to year.
- Sugito
doaj
Some Introductory Notes on the Development and Characteristics of Sabah Malay [PDF]
, 2011 This is a preliminary description of the Malay variety used as a lingua franca in the Malaysian state of Sabah at the northernmost top of Borneo. The paper discusses a number of common linguistic features that distinguish Sabah Malay from other Malay ...
Jing Cheng (41407) +1 more
core +4 more sources