Results 61 to 70 of about 66,268 (258)

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Early Modern Science in Translation: Texts in Transit Between Italy and England [PDF]

open access: yes, 2019
This paper aims to take a fresh look at the emergence of a new linguistic culture at the end of the seventeenth century in England, when the Restoration, the birth of the Royal Society and the spread of the experimental scientific method posed the ...
Plescia, Iolanda
core  

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

An investigation on levels of the emphatic tendencies of classroom teachers

open access: yesJournal of Human Sciences, 2010
Bu araştırmada, sınıf öğretmenlerinin empatik eğilimlerinin bazı değişkenler açısından incelenmesi amaçlanmıştır. Araştırmanın evreni 2009–2010 öğretim yılında Düzce ilinde görev yapan 1257 sınıf öğretmenidir. Örneklemi ise bu evrenden basit tesadüfî örnekleme yoluyla seçilmiş 307 sınıf öğretmeni oluşturmaktadır.
Akbulut, Emine, Sağlam, Halil İbrahim
openaire   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Investigation of preferred leadership behaviors in sport and empathic tendency with regards to different variables

open access: yesTürk Spor ve Egzersiz Dergisi, 2016
This study was conducted in order to explore the emphatic tendencies of students receiving education at the School of Physical Education and Sport as well as the leadership behaviors they prefer with regard to different variables.
Gaye Erkmen, Mehibe Akandere
doaj  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Seeing Whiteness on the Gallery Wall: Race Through the Prism of Three Early Modern Portraits

open access: yesMuseum & Society
I am frequently told how race in the early modern period had little do with colour, and instead signified lineage, class, and gender. Therefore, any attempts to racialise the period is anachronistic.
Janet Couloute
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Fronted nuclei: narrow focus in Spanish and English

open access: yesBucharest Working Papers in Linguistics, 2009
This paper is an attempt to show that fronted nuclei, if not as abundant as in English, do nevertheless, along with other means of highlighting, play a significant role in Spanish intonation. Although the overriding tendency in Spanish is for right-edged
Brian Mott
doaj  

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