Results 111 to 120 of about 166,944 (283)
Imaging of pulmonary emphysema: A pictorial review
International Journal of COPD, 2008 Masashi Takahashi1, Junya Fukuoka2, Norihisa Nitta1, Ryutaro Takazakura1, Yukihiro Nagatani1, Yoko Murakami1, Hideji Otani1, Kiyoshi Murata11Department of Radiology, Shiga University of Medical Science, Shiga, Japan; 2Laboratory of Pathology, Toyama ...
Masashi Takahashi +5 more
doaj
EBioMedicine, 2018 Aims: Autoimmune conditions such as rheumatoid arthritis-related interstitial lung disease (RA-ILD) have been linked to the existence of emphysema in never-smokers. We aimed to quantify emphysema prevalence in RA-ILD never-smokers and investigate whether
Joseph Jacob +12 more
doaj +1 more source
Degradomics for large‐scale mechanistic insights on proteases and proteolysis in human health
The FEBS Journal, EarlyView.Proteolysis has an important role in human disease but remains relatively unexplored. Degradomics, the uncovering of proteolysis in tissues, cells, and proteins, uses mass spectrometry‐based terminomics to identify protein termini occurring therein (forward degradomics) and to define the actions of proteases (reverse degradomics).
Daniel R. Martin +2 more
wiley +1 more source
The FEBS Journal, EarlyView.The extracellular matrix (ECM) is a dynamic scaffold that orchestrates tissue architecture and cellular communication. A critical but underexplored interplay between proteases and cluster of differentiation molecules (CD) governs ECM turnover and directs cell fate.
David Jurnečka +3 more
wiley +1 more source
Tissue Resident Memory Cells: Friend or Foe?
Immunology, EarlyView.Tissue‐resident memory T cells (TRM cells) are specialised immune cells in barrier tissues like the lungs, skin and gut, providing rapid host defence and tumour surveillance. Their retention and differentiation are regulated by molecules such as CD69, CD103 and TGF‐β. Dysregulation of TRM cells can lead to chronic activation, driving conditions such as
Chidimma F. Chude +2 more
wiley +1 more source
Emphysema: an ignored radiologic sign of diffuse alveolar hemorrhage
BMC PediatricsBackground Diffuse alveolar hemorrhage (DAH) is characterized by the presence of diffuse ground glass opacities and/or consolidation on chest CT. Emphysema has been reported occasionally.
Fu-ce Lu +9 more
doaj +1 more source
Journal of Clinical Periodontology, EarlyView.ABSTRACT Introduction This explanatory pilot study presents a workflow to identify approved drugs, which could be repurposed for periodontitis therapy using salivary proteomics combined with drug‐target database screening. Methods Proteomic analyses of saliva using LC–MS/MS were conducted in two independent settings: a cohort (sub‐study I, N = 187) and
Taisir Bozo +11 more
wiley +1 more source