Results 121 to 130 of about 218,651 (379)

Matrix Remodeling in Pulmonary Fibrosis and Emphysema.

American Journal of Respiratory Cell and Molecular Biology, 2016
Pulmonary fibrosis and emphysema are chronic lung diseases characterized by a progressive decline in lung function, resulting in significant morbidity and mortality.
T. Kulkarni, Philip J. O’Reilly, V. Antony, A. Gaggar, V. Thannickal   +4 more
semanticscholar   +1 more source

Nanoparticle Therapeutics in Clinical Perspective: Classification, Marketed Products, and Regulatory Landscape

Small, EarlyView.
This review presents a detailed overview of clinically approved nanoparticle therapeutics, classifying them by type and discussing their unique advantages in drug delivery. It highlights regulatory challenges across global markets and emphasizes the need for adaptive approval pathways.
Nimeet Desai, Dhwani Rana, Mitali Patel, Neha Bajwa, Rajendra Prasad, Lalitkumar K. Vora   +5 more
wiley   +1 more source

Nanozymes in Reactive Oxygen Species‐Dependent Diseases: From Design and Preclinical Studies to Clinical Translation Prospects

Small Structures, EarlyView.
Nanozymes emerge as promising therapeutic agents for reactive oxygen species (ROS)‐dependent diseases, offering advantages over traditional biocatalysts through enhanced stability, tunability, and targeting capabilities. This review explores their mechanisms, design strategies, and clinical progress, emphasizing precision medicine potential.
Lihong Zhou, Jingyu Yan, Chenying Cui, Yurong Xu, Kaifang Zhang, Meijun Du, Zhuowei Zhang, Xiuping Wu, Bing Li   +8 more
wiley   +1 more source

Emphysema

, 2020
Emphysema (Greek word meaning to inflate/to blow) is an increase in the size of airspace distal to the terminal bronchiolus, that is, hyperinflation of the alveoli due to the destruction of the gas-exchanging structures: alveolar walls, alveolar ducts, and respiratory bronchioles with coalescence of airspaces into the abnormal, much larger airspaces ...
openaire   +3 more sources

Diagnosis and Monitoring Pathways Using Non‐Invasive Tests in Patients With Alpha‐1 Antitrypsin Deficiency‐Associated Liver Disease: Results From an Expert Delphi Panel

United European Gastroenterology Journal, EarlyView.
ABSTRACT Background and Aims The severe alpha‐1 antitrypsin deficiency (AATD) genotype Pi*ZZ increases the risk of liver disease (AATD‐LD) and lung disease. While non‐invasive tests (NITs) are widely used for fibrosis stage and monitoring of all liver diseases, the consensus for use in AATD‐LD is limited.
Virginia C. Clark, Mark A. Price, Jon Russo, Rohit Loomba, Alice M. Turner, Pavel Strnad   +5 more
wiley   +1 more source

Gastric dilatation secondary to incarceration through a gastrosplenic omental rent in a dog

Veterinary Record Case Reports, EarlyView.
Abstract A 2‐year‐old, entire, female Dogue de Bordeaux presented with inappetence and abdominal distension. Radiographs revealed gastric dilatation and malpositioning. Given the absence of classical signs of gastric dilatation and volvulus, a medical approach was elected. After 24 hours, the dog's condition deteriorated.
Clara Galvani, Francesca Saponaro, Giacomo Galvani, Arrigo Galvani, Giliola Spattini   +4 more
wiley   +1 more source

Why are our roe deer short of breath? – prevalence and promotive factors of lung parasites in roe deer Capreolus capreolus in south‐eastern Germany

Wildlife Biology, EarlyView.
The existence of bronchopulmonary nematodes in German roe deer Capreolus capreolus is well documented, with two types of lung parasites that have been described previously: Dictyocaulus capreolus and Varestrongylus capreoli. However, little is known about the impact of these parasites on their host animal or which parameters influence outbreak and ...
Tobias Wild, Christian Ehrmantraut, Sarah‐Alica Dahl, Felix Langer, Elisabeth Kiess, Kathrin Simon, Markus Meissner, Andreas König   +7 more
wiley   +1 more source

Prevalence and Effects of Emphysema in Never-Smokers with Rheumatoid Arthritis Interstitial Lung Disease

EBioMedicine, 2018
Aims: Autoimmune conditions such as rheumatoid arthritis-related interstitial lung disease (RA-ILD) have been linked to the existence of emphysema in never-smokers. We aimed to quantify emphysema prevalence in RA-ILD never-smokers and investigate whether
Joseph Jacob, Jin Woo Song, Hee-Young Yoon, Gary Cross, Joseph Barnett, Wen Ling Woo, Fern Adams, Maria Kokosi, Anand Devaraj, Elisabetta Renzoni, Toby M. Maher, Dong Soon Kim, Athol U. Wells   +12 more
doaj   +1 more source

Emphysema in active farmer’s lung disease

PLoS ONE, 2017
Background Farmer’s lung (FL) is a common type of hypersensitivity pneumonitis. It is often considered that fibrosis is the most frequent finding in chronic FL.
T. Soumagne, M-L Chardon, G. Dournes, L. Laurent, B. Degano, F. Laurent, J. Dalphin   +6 more
semanticscholar   +1 more source

Virus‐Induced Cellular Senescence Causes Pulmonary Sequelae Post‐Influenza Infection

Aging Cell, EarlyView.
Genetic or pharmacological depletion of senescent cells during influenza A virus infection led to complete recovery of the airway epithelium, indicating a marked acceleration of the epithelial repair process. Targeting senescent cells may represent a new preventive therapeutic option to reduce post‐influenza chronic lung damage.
Larissa Lipskaia, Lou Delval, Valentin Sencio, Emmanuelle Born, Séverine Heumel, Amal Houssaini, Clara Valentin, Stefano Raviola, Lucie Deruyter, Fabiola Silva Angulo, Vincent Gros, Elisabeth Marcos, Shariq Abid, Mira Goekyildirim, Vanessa Contreras, Jean Michel Flaman, Roger Le Grand, Ronan Le Goffic, David Bernard, Serge Adnot, François Trottein   +20 more
wiley   +1 more source