Results 121 to 130 of about 34,446 (251)

Exploring new avenues: Psychedelic‐assisted therapy for young people

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Rates of mental illness in young people are increasing, whereas the development of novel mental health treatments has not significantly progressed. Psychedelic‐assisted therapy, using substances such as psilocybin and 3,4‐methylenedioxymethamphetamine (MDMA), has shown potential in the treatment of mental illnesses in the adult population, including ...
Ioanna Artemis Vamvakopoulou   +3 more
wiley   +1 more source

Adaptive imatinib regimens can mitigate cumulative toxicity while sustaining hemodynamic benefit: A model‐based simulation of the positioning imatinib for pulmonary arterial hypertension trial

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
ABSTRACT Aims Imatinib improves hemodynamics in pulmonary arterial hypertension (PAH), but dose‐dependent toxicity has limited its clinical development. We aimed to quantify the dose–efficacy–toxicity relationship and evaluate alternative dosing strategies using data from the PIPAH trial.
Medhat M. Said   +13 more
wiley   +1 more source

«…THEN I DISARRAYED THE TURKIC ELL, THEN I RUINED IT". THE TURKIC KHAGANATES FALL: FACTORS AND MECHANISMS

open access: yesВестник Кемеровского государственного университета, 2014
The paper deals with the basic factors and mechanisms of the fall of the Turkic nomadic tribes in Mongolia. The research is based on the complex analysis of the factors and reasons which determined the schism or liquidation of the Turkic empires.
S. A. Vasyutin
doaj  

‘…It was my choice to see how I can acquire this Western world education… and I'm happy…’: Structuration and the dialectic nature of being a Nigerian university student in the UK

open access: yesBritish Educational Research Journal, EarlyView.
Abstract This paper examines the experiences of Nigerian cross‐border students in UK higher education, focusing on how colonial legacies continue to shape the interplay between structure and agency. Three key themes emerged in the analysis of the data: First, the persistence of a ‘West is Best’ mentality reflects the internalisation of colonial ...
Jennifer Marshall, Jack Bryne Stothard
wiley   +1 more source

Séance 11. Empires et gouvernance, 16 novembre 2018, 13h30-16h30, salle G 203, bat. G Stendhal, UGA

open access: yes, 2018
Andreas Nijenhuis-Bescher, Associate Professor Hankuk University (Corée du Sud) "L’Empire avant l’impérialisme : la création et le développement des possessions coloniales néerlandaises, XVIIe siècle - XIXe siècle" « Les Hollandais sont des hommes ...
empires
core  

Characterization of Immune Responses to RBD‐SD1 Nanoparticle Vaccines Derived From ACE2‐Capable HKU5‐CoV‐2, NeoCoV, and HKU5 Merbecoviruses

open access: yesBiotechnology and Bioengineering, EarlyView.
SpyCatcher‐mi3 nanoparticles presenting HKU5, NeoCoV, and HKU5‐CoV‐2 RBD‐SD1 induced strong, cross‐reactive IgG responses in immunized mice. The surrogate virus neutralization test demonstrated strong activity in sera from homologous vaccination. ABSTRACT Recent discoveries of merbecoviruses such as HKU5, NeoCoV, and HKU5‐CoV‐2 that use angiotensin ...
Peter J. Halfmann   +11 more
wiley   +1 more source

Cryo‐EM Analysis of Adenovirus Vector Reveals Purification Conditions Leading to Loss of Viral Fiber Proteins and Reduced Infectivity

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Vaccines and gene therapies require efficient delivery of genetic material to host cells. Viral vectors leverage viruses' ability to enter host cells to achieve this. Following the SARS‐CoV‐2 vaccine and novel gene therapies that utilize adenovirus vectors, there has been an increase in the demand for large‐scale production of vectors.
Betsy Widdicombe   +7 more
wiley   +1 more source

Empire, Islam and the postcolonial [PDF]

open access: yes, 2012
One of the most persistent criticisms of postcolonialism is that it promotes an antipathy to imperialism that tends to focus on the experience of European colonial empires and neglects other, non-western instances of imperial hubris.
S. Sayyid
core  

Bridging Historical, Archaeological and Criminal Networks

open access: yesJournal of Computer Applications in Archaeology
Lena Tambs   +3 more
doaj   +1 more source

Empires of the Silk Road A History of Central Eurasia from the Bronze Age to the Present

open access: yes
The first complete history of Central Eurasia from ancient times to the present day, Empires of the Silk Road represents a fundamental rethinking of the origins, history, and significance of this major world region.
Beckwith, Christopher I.   +1 more
core  

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