Results 41 to 50 of about 3,527,427 (311)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
empirical-contribution-archive.zip
, 2019 Empirical study of the contribution of evidence in Network meta-analysisThe archive contains all data and functions for reproducing the analysis and produce the manuscript.
Theodoros Papakonstantinou (6554228)
core +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Intonation and timing in singing early music is unrelated to respiration synchronization
Scientific ReportsMusical ensemble performance offers a unique context for investigating complex interpersonal coordination. Hyperscanning research revealed the synchronization of physiological processes during coordinated musical interaction.
Anton Schreiber +2 more
doaj +1 more source
Entropy, 2020 Background: This investigation included both a study of potential non-invasive diagnostic approaches for the bladder cancer biomarker UBC® Rapid Test and a study including comparative methods about sensitivity–specificity characteristic (SS-ROC) and ...
Peter Oehr, Thorsten Ecke
doaj +1 more source
NRLMSIS 2.0: A Whole‐Atmosphere Empirical Model of Temperature and Neutral Species Densities
Earth and Space Science, 2021 NRLMSIS® 2.0 is an empirical atmospheric model that extends from the ground to the exobase and describes the average observed behavior of temperature, eight species densities, and mass density via a parametric analytic formulation.
J. T. Emmert +16 more
doaj +1 more source
TQM implementation: An empirical examination and proposed generic model [PDF]
, 2001 Total quality management (TQM) is considered by many as an important quality and business performance improvement tool. The popularity of the concept has led to an explosion of TQM related literature.
Ghobadian, A +3 more
core +1 more source
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Using empirical studies during software courses
, 2022 S.81-103A number of empirical studies using students as subjects has been carried out in the last few years. These studies are usually conducted as pilot experiments that allow researchers to fine-tune an experiment before deploying it in an industrial ...
Carver, J. +3 more
core +1 more source