Results 41 to 50 of about 1,978,218 (342)

Learning Processes and Acquisition of Knowledge and Skills in Training and Supervision of Psychotherapy and Counselling: A Study Protocol for a Scoping Review

Frontiers in Psychology, 2021
Background: Increased awareness of the individual therapist’s vital contribution to treatment processes and outcome, and the potential role of training and supervision in this respect, warrants a close look at the empirical and theoretical literature on ...
Hanne Weie Oddli, Erkki Heinonen, Erkki Heinonen, Stephan Hau, Jan Nielsen, Rachelle Esterhazy, Cecilie Hillestad Hoff, Hanne Strømme   +7 more
doaj   +1 more source

The reflective learning continuum: reflecting on reflection [PDF]

, 2005
The importance of reflection to marketing educators is increasingly recognized. However, there is a lack of empirical research which considers reflection within the context of both the marketing and general business education literature.
Amanda Hay, Argyris, C., Bennis, W., Biggs, J., Bloom, B. S., Boud, D., Boud, D., Braun, N. M., Densten, I. L., Dewey, J., Entwhistle, N., James W. Peltier, Kolb, D. A., Kouzes, J. M., Loo, R., Marton, F., Mezirow, J., Mintzberg, H., Mintzberg, H., Mukherjee, A., Nunnally, J., Porter, L., Schön, D. A., Schön, D. A., Stevens, G. E., Taylor, E., William Drago, Willmott, H.   +27 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Theoretical Validity and Empirical Utility of a Constructionist Analytics [PDF]

, 2012
Wing-Chung Ho offers an extensive critique of what he calls our “radical constructionist approach to family experience,” questioning the theoretical validity and empirical utility of the research program.
Gubrium, Jaber F., Holstein, James A
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Earthkeepers: The Relationship between Instructional Strategies on the Program Outcomes

Envigogika, 2022
The study focuses on the relationship between selected characteristics of the outdoor environmental (earth) education program Earthkeepers and its impacts on students' environmental values and knowledge.
Jan Činčera, Bruce Johnson
doaj   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source

Popper’s and Lakatos’s philosophies of science: main differences

Актуальні проблеми духовності
The article compares Karl Popper’s and Imre Lakatos’s conceptions of the development of scientific knowledge. It is argued that the central difference between these conceptions relates to Lakatos’s thesis about the structure of scientific research ...
Dmytro Sepetyi
doaj   +1 more source