Results 201 to 210 of about 2,042,267 (364)

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

PENGARUH IKLIM ORGANISASI TERHADAP INTENTION TO STAY PADA PT MUSLA TRANS UTAMA DENGAN EMPLOYE ENGANGEMENT SEBAGAI VARIABEL INTERVENING [PDF]

Penelitian bertujuan untuk mengetahui serta menganalisis pengaruh iklim organisasi terhadap intention to stay pada PT Musla Trans Utama dengan employee engangement sebagai variabel intervening.
Iffa, Annisa' Nurul
core  

A cluster-based human resources analytics for predicting employee turnover using optimized Artificial Neural Networks and data augmentation

Mohammad Reza Shafie, Hamed Khosravi, Sarah Farhadpour, Srinjoy Das, Imtiaz Ahmed   +4 more
openalex   +1 more source

Is it Time to Intentionally Improve the Satisfaction of Health Care Employees?

, 2023
Terry L. Hunt, Colin P. West, Jonathan A. Leighton, Paul S. Mueller   +3 more
openalex   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Explainable attrition risk scoring for managerial retention decisions in human resource analytics. [PDF]

Front Big Data
Pavithran MS, Vadivel SM.
europepmc   +1 more source

Visual Analysis of the Employee Performance Research Literature

, 2023
XiuPing Liu
openalex   +2 more sources

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Unhappy Working with Men? Workplace Gender Diversity and Employee Job-Related Well-Being in Britain: A WERS2004 Based Analysis [PDF]

This paper attempts to establish empirically the link between workplace gender diversity and employee job-related well-being. Using nationally representative linked employer-employee data for Britain, I employ econometric techniques that account for ...
Haile, Getinet Astatike
core  

RELATIONSHIP BETWEEN BRAND KNOWLEDGE AND BRAND REWARDS, AND EMPLOYEES' BRAND CITIZENSHIP BEHAVIOR: THE MEDIATING ROLES OF BRAND COMMITMENT [PDF]

, 2012
Hasnizam Shaari, Salniza Md. Salleh, Zolkafli Hussin   +2 more
openalex