Results 41 to 50 of about 707,181 (277)

Effect of Employees Training, Employees Motivation, Employees Development on Employees Retention

Journal of Management Research, 2015
This research is conducted on the basis of studying the effect of employee’s retention in private universities of Peshawar, Pakistan taking the focus on the case of iqra national university as center point the word retention stands for the ability of an organization to retain their employees and to safe their good quality employees so in order to study
Fatima, Ayesha, Anwar, Shazeb
openaire   +2 more sources

Increased imaging ligand hydrophilicity and improved pharmacokinetic properties provides enhanced in vivo targeting of fibroblast activation protein

npj Imaging
In this work, the impact of physicochemical modifications on pharmacokinetics and in vivo targeting of a small molecule fibroblast activation protein inhibitor (FAPI) imaging ligand in a murine model of rheumatoid arthritis was evaluated.
Radhika Narain, Ian Nessler, Paul L. Richardson, Jamie E. Erickson, Yuzhen Wang, Jacqueline Ferri, Heather L. Knight, Shaughn H. Bryant, Lucy A. Phillips, Liang Zhang, Soumya Mitra   +10 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

Employee Engagement and Employee Turnover

Indian Journal of Applied Research, 2011
In today's context, most of the Indian business organizations are facing a paradoxical problem so far as employment of their human resources is concerned. On one hand, they are facing the problem of overstaff- ing and are busy to pruning the surplus staff through voluntary retirement and other schemes.
Dr. C. SWARNALATHA Dr. C. SWARNALATHA, T. S. PRASANNA T. S. PRASANNA   +1 more
openaire   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Employee Retention and Employee Engagement [PDF]

International Journal of Management, 2020
This article aims to study the relationship between high employee engagement and employee retention. The study was conducted in October 2018, on NTPC Ltd. which is the largest power plant in India. Annual Report of NTPC Ltd. in the year 2016-17 reflected the total employee strength of the Company (including JVs/subsidiaries) was 22,124 as of 31.3.2017 ...
openaire   +2 more sources

Doxycycline as a potential partner of COVID-19 therapies

IDCases, 2020
Coronavirus disease 2019 (COVID-19) is a major public health challenge, and the current antiviral arsenal for treatment is limited, with questionable efficacy.
Alexandre E. Malek, Bruno P. Granwehr, Dimitrios P. Kontoyiannis   +2 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Long-term safety and effectiveness of lurasidone in adolescents and young adults with schizophrenia: pooled post hoc analyses of two 12-month extension studies

Annals of General Psychiatry
Background and Objectives The aim of this analysis was to evaluate the long-term safety and effectiveness of lurasidone in the treatment of schizophrenia in adolescents and young adults (13–25).
Fabrizio Calisti, Michael Tocco, Yongcai Mao, Robert Goldman   +3 more
doaj   +1 more source