RIPK4 function interferes with melanoma cell adhesion and metastasis
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
One size does not fit all: Nurturing identity needs and job satisfaction through employee benefits across gender and age. [PDF]
Valmori A, Reverberi E, Manzi C.
europepmc +1 more source
Sustainable management: a strategic challenge for a global minerals and metals industry
This paper refers to the concept of sustainable management as the management approach which efficiently integrates economic, environmental and social issues into the operations of the minerals and metals industries, with the aim of creating long-term ...
Botin Gonzalez, Jose Antonio +1 more
core
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
AI-Savvy leadership for enhancing AI utilization and employee engagement among digital natives in the EdTech sector. [PDF]
Quttainah MA +5 more
europepmc +1 more source
Homologous expression and purification of human HAX‐1 for structural studies
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley +1 more source
Digital transformation in human resource department (HRD) within performance appraisal process is initiated from employee management and supported by the commitment of leaders to create aspects of openness and fairness. In this context, PT.
Alexander Wirapraja +2 more
doaj
Psychological pathways between leadership behavior and work-family balance: the mediating roles of employee satisfaction and perceived support. [PDF]
Wang P, Lyu B, Yang Q, Wan Q.
europepmc +1 more source
Overview of molecular signatures of senescence and associated resources: pros and cons
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
Enhancing Strategic Agility and Real Time Decision-Making in the Technology Sector: Exploring the Role of AI and e-HRM Systems. [PDF]
Ongesa Nyamboga T.
europepmc +1 more source

