Results 201 to 210 of about 1,071,381 (324)

Alleviation of Aging‐Related Hallmarks in a Mouse Model of Progeria via a Nanoparticle‐Based Artificial Transcription Factor

open access: yesAdvanced Functional Materials, EarlyView.
Oct4‐nanoscript, a biomimetic nanoparticle‐based artificial transcription factor, precisely regulates cellular rejuvenation by activating Oct4 target genes, restoring epigenetic marks, and reducing DNA damage. In a progeria model, it effectively rescued aging‐associated pathologies and extended lifespan.
Hongwon Kim   +8 more
wiley   +1 more source

Strategies to Design and Optimize Artificial Antigen‐Presenting Cells for T Cell Expansion in Cancer Immunotherapy

open access: yesAdvanced Functional Materials, EarlyView.
This review highlights recent advances in engineering artificial antigen‐presenting cells (aAPCs) as alternatives to dendritic cells for T cell expansion. Key design principles inspired by the immunological synapse are discussed, with emphasis on strategies for polyclonal and antigen‐specific T cell expansion.
Nguyen Thi Nguyen, Yu Seok Youn
wiley   +1 more source

Intraoral Drug Delivery: Bridging the Gap Between Academic Research and Industrial Innovations

open access: yesAdvanced Functional Materials, EarlyView.
Intraoral drug delivery offers a promising route for systemic and localized therapies, yet challenges such as enzymatic degradation, limited permeability, and microbial interactions hinder efficacy. This figure highlights innovative strategies—mucoadhesive materials, enzyme inhibitors, and permeation enhancers—to overcome these barriers.
Soheil Haddadzadegan   +4 more
wiley   +1 more source

Dynamic Networks via Polymerizable Deep Eutectic Monomers for Uniform Li+ Transport at Interfaces in Lithium Metal Batteries

open access: yesAdvanced Functional Materials, EarlyView.
The PDEM‐based SIGPE provides a dynamic nanophase from Li+‐bridged molecular self‐association, enhancing electrochemical stability and facilitating uniform Li+ ion flux at the interface. This unique solvation structure results in a hetero species‐driven inorganic‐rich SEI and long‐term cycle stability, suggesting that a PFAS‐free Li+‐containing monomer
Susung Yun   +5 more
wiley   +1 more source

Excitonic Emission Modulation in GaSe/MoS2 Van Der Waals Heterostructure Via Plasmonic Control of Interlayer Charge Transfer

open access: yesAdvanced Functional Materials, EarlyView.
Plasmonic hybridization enables control of light emission in 2D van der Waals heterojunctions. By stacking multilayer GaSe and monolayer MoS2 on a silver film, light emission is enhanced at the edges due to plasmonic effects. In the center, where these effects are absent, charge transfer led to reduced light emission.
Jung Ho Kim   +5 more
wiley   +1 more source

The Frontiers of Aqueous Zinc–Iodine Batteries: A Comprehensive Review on Mechanisms, Optimization, and Industrial Prospects

open access: yesAdvanced Functional Materials, EarlyView.
This review provides an in‐depth understanding of all theoretical reaction mechanisms to date concerning zinc–iodine batteries. It revisits the inherent issues and solutions of zinc–iodine batteries from the perspective of industrial application. By integrating existing examples of energy storage applications, it identifies the challenges faced on the ...
Haokun Wen   +10 more
wiley   +1 more source

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