Results 31 to 40 of about 65,163 (294)

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Does It Pay to Volunteer? The Relationship Between Volunteer Work and Paid Work [PDF]

open access: yes, 2013
It is widely believed that volunteering will improve workers' job prospects. The logic is that volunteering offers opportunities to expand work-related experience, develop new skills, and build a network of professional contacts.
Helene Jorgensen
core  

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

Employee Volunteering and the Special Constabulary: A Review of Employer Policies [PDF]

open access: yes, 2002
The research conducted for this study had three broad aims. The first of these was to examine the attitudes of large employers in the private sector to staff participation in voluntary work.
Jacobson, Jessica, Millie, Andrew
core   +2 more sources

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

Social Responsibility Initiatives Supporting Ngos in Oradea Municipality

open access: yesBulletin of the Transilvania University of Braşov: Series VII: Social Sciences, Law
The paper highlights the main needs and challenges faced by non-governmental organizations that provide social services in the municipality of Oradea and analyzes how they are supported by corporate social responsibility actions.
C. Bacter, C. Marc
doaj   +1 more source

Frailty Exacerbates Disability in Progressive Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background To evaluate frailty in severe progressive multiple sclerosis (PMS) and to investigate the underlying mechanisms. Methods This prospective, cross‐sectional, multicenter study enrolled a late severe PMS group requiring skilled nursing (n = 53) and an age, sex, and disease duration‐matched control PMS group (n = 53).
Taylor R. Wicks   +10 more
wiley   +1 more source

A systematic review of how volunteering relates to job satisfaction and job performance

open access: yesDiscover Psychology
Background Volunteering is increasingly recognised for its benefits to individuals and organisations, yet its impact on workplace outcomes remains underexplored.
Dylan Bansi   +3 more
doaj   +1 more source

Volunteering in medical school during the pandemic: a solution for teaching

open access: yesMedEdPublish, 2020
Introduction: On March 18, 2020, in face of COVID-19 pandemic and the suspension of in-person activities by the Board of the Paulista School of Medicine (EPM), students on clinical rotations (5th and 6th grades) organized themselves to support the local ...
Daniela Mendes Chiloff   +8 more
doaj  

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