Results 41 to 50 of about 86,400 (218)
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo +5 more
wiley +1 more source
From Campus to Career: The Influence of Soft Skills on Employability
World economies have become more globalized and interconnected, with new advanced aspects of employment that are highly automated and technological. This leads to new work requirements that have rapidly been evolving since the beginning of the twenty ...
Rachid Elkhayma, Mohamed Ezzaidi
doaj +1 more source
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa +7 more
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Labor market integration of refugees in Germany: Employers’ experiences and consequences
In the light of a recent surge of refugee migration to Germany, labor market integration as well as employers’ experiences and consequences are key determinants of immigration’s macroeconomic welfare impacts.
Marlene Saal, Juergen Volkert
doaj
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Characteristics of the control implemented by the employment agency on labour programmes and measures [PDF]
The subject of consideration of this study is the control procedures implemented by officials of the Employment Agency (EA) regarding the control on employers participating in subsidized employment programmers and measures. The purpose of the study is to
Svetlozar Stefanov
doaj
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Purpose: the main purpose of this article is to improve forecast-oriented management of the segmentation of regional labour markets for the professions that are in greatest demand in the main groups of the All-Russian Classifier of Occupations.
V. V. Harkin
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source

