Entering the World of Work: What Youth With Mental Health Needs Should Know About Accommodations [PDF]
[Excerpt] Starting a job can be difficult for any young person. If you happen to have a hidden disability, such as a mental health impairment, a new workplace can be overwhelming. If you have ever felt this way, you are not alone.
Office of Disability Employment Policy
core +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Increasing Options: The Ticket To Work And Self-Sufficiency Program [PDF]
[Excerpt] The Ticket to Work and Self-Sufficiency Program is an avenue to employment for people with disabilities who want to join or reenter the workforce.
Office of Disability Employment Policy
core +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
This article uses the metaphor of a social contract to review the evolution of American unions and their effects— especially in the variations in their quality—on firm employment strategies and performance, takes stock of the current state of unions and ...
Thomas A. Kochan, William T. Kimball
doaj +1 more source
Q & A on Customized Employment: Assistive Technology as a Workplace Support [PDF]
[Excerpt] Despite the promise of assistive technology, many people with significant physical disabilities remain in facility-based employment programs. Underutilization of AT to facilitate competitive employment is related to a number of critical issues.
Office of Disability Employment Policy
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Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Sharia-Compliant Investment Forecasting to Support Green Industrial and Energy Transition in Indonesia [PDF]
Fluctuating stock prices in the capital market provide significant opportunities for investors to profit from price differences. According to data from the Financial Services Authority (OJK), sharia-compliant stocks experience stable growth and tend to ...
Maulia Lyfia Indah +9 more
doaj +1 more source
Maximizing Productivity: Accommodations for Employees with Psychiatric Disablities [PDF]
[Excerpt] Reasonable accommodations are adjustments to a work setting that make it possible for qualified employees with disabilities to perform the essential functions of their jobs.
Office of Disability Employment Policy
core +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source

