Results 101 to 110 of about 1,426,959 (343)

The employer's perspective: employment of people with disabilities in wage subsidized employments

open access: yesScandinavian Journal of Disability Research, 2013
The aim of this article is to examine employers' perspectives of the conditions of employment of people with disabilities within a context of wage subsidies. Employers in different workplaces were interviewed, and the interviews were analysed according to qualitative content analysis (Graneheim and Lundman 2004).
Johanna Gustafsson   +2 more
openaire   +5 more sources

Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer

open access: yesMolecular Oncology, EarlyView.
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia   +17 more
wiley   +1 more source

Collective bargaining: building solidarity through the fight against inequalities and discrimination

open access: yesCuadernos de Relaciones Laborales, 2014
Equality bargaining in essence is turning the resource of collective bargaining to the objectives of equality and diversity in work and employment. This article traces the progress of equality bargaining, with a focus on the UK.
Stephanie Tailby, Sian Moore
doaj   +1 more source

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

open access: yesMolecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka   +10 more
wiley   +1 more source

Incarceration, Recidivism, and Employment

open access: yesJournal of Political Economy, 2016
Using a random judge design and panel data from Norway, we estimate that imprisonment discourages further criminal behavior, with reoffense probabilities falling by 29 percentage points and criminal charges dropping by 11 over a 5-year period.
Manudeep Bhuller   +3 more
semanticscholar   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

open access: yesMolecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

open access: yesMolecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes   +20 more
wiley   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

Employee Engagement and Financial Performance among SMEs in Lagos State, Nigeria

open access: yesABUAD Journal of the Humanities-AGIDIGBO, 2018
This article examines the influence of employee engagement on financial performance of SMEs in Lagos State, Nigeria, using a survey research design with a random selection of 450 respondents from a population of 4,535 small and medium enterprises in ...
Akeem A. Akinwale, Paul O. Ogunyomi
doaj   +1 more source

Home - About - Disclaimer - Privacy