Results 61 to 70 of about 37,243 (266)

Analysis of the Labor Market Situation of People with Disabilities

open access: yesActa Universitatis Lodziensis. Folia Oeconomica, 2018
People with disabilities belong to a social group at risk of poverty. In their daily lives, they face prejudice and obstacles in the labor market. The purpose of this paper is to analyze and assess the labor market situation of people with disabilities ...
Lidia Zofia Jabłońska‑Porzuczek   +1 more
doaj   +1 more source

A Clinical Study of Decellularized Tissue Engineering Hyaline Cartilage Graft (dLhCG) for Articular Cartilage Repair

open access: yesAdvanced Science, EarlyView.
ABSTRACT Current clinical approaches for knee cartilage repair are often limited by hypertrophy and fibrosis in the regenerated tissues. A decellularized tissue‐engineered hyaline cartilage graft (dLhCG), composed of a type II collagen‐based extracellular matrix, has been developed to overcome this limitation.
Zhen Zhang   +16 more
wiley   +1 more source

Ultrasound‐Responsive Piezoelectric Fibrous Membrane Promotes Neurological Recovery After TBI by Modulating Microglial Polarization via Restoring Mitochondrial Dynamic Homeostasis

open access: yesAdvanced Science, EarlyView.
We demonstrate a novel therapy for traumatic brain injury TBI using a LIPUS‐responsive Piezoelectric fibrous membrane. It targets microglial mitochondria via in situ electrical signals, restoring homeostasis and reducing oxidative stress to promote an anti‐inflammatory M2 phenotype.
Wei Li   +9 more
wiley   +1 more source

Legal Regulation Problems of Employment Quoting for People with Disabilities

open access: yesVestnik Omskoj Ûridičeskoj Akademii, 2014
The article deals with the definition of employment quoting, the analysis of changes in legal regulation of employment quotas for people with disabilities during the last decade, here is considered the effectiveness of employment quotas as the means of ...
Zhavoronkov R. N.
doaj  

AI Designed Conformation Locking Peptides Target STING to Restore Diabetic Wound Healing

open access: yesAdvanced Science, EarlyView.
A generative AI pipeline identifies SCP‐1, a conformation‐locking peptide that stabilizes inactive STING. Incorporated into a dual‐responsive hydrogel for localized, MMP‐9‐triggered release, SCP‐1 suppresses inflammation, promotes reparative macrophage polarization, and accelerates diabetic wound healing.
Xinyu Li   +8 more
wiley   +1 more source

Personal readiness for employment among students with disabilities

open access: yesПсихологическая наука и образование
Context and relevance. In the context of labor shortage, employment issues for people with disabilities are of particular importance. The low level of employment of people with disabilities necessitates studying the psychological factors that ...
O.L. Lekhanova   +2 more
doaj   +1 more source

ZBTB18 Dysfunction Promotes Neuropathic Pain via CHD4‐based Epigenetic Disinhibition of CLIC1 Channels in Sensory Neurons

open access: yesAdvanced Science, EarlyView.
In this study, we identify a novel functional role of ZBTB18 in regulating trigeminal‐mediated neuropathic pain. Nerve injury reduces ZBTB18 in trigeminal ganglion neurons, impairing CHD4/NuRD recruitment and de‐repressing Clic1. Elevated CLIC1 enhances chloride channel activity and neuronal hyperexcitability, thereby driving pain.
Shoupeng Wang   +11 more
wiley   +1 more source

Nrsn1–Smarcc1 Coupling Regulates Neural Stem Cell Differentiation and Chronic‐phase Recovery After Ischemic Stroke

open access: yesAdvanced Science, EarlyView.
In the post‐stroke brain, Foxa2 induces the transcriptional upregulation of Nrsn1 in NSCs. Nrsn1 functionally couples with Smarcc1, modulating its nuclear availability and protein abundance, thereby influencing Smarcc1‐associated regulatory programs linked to neuronal lineage commitment. Through this coupling, Nrsn1 promotes the differentiation of NSCs
Ruolin Zhang   +18 more
wiley   +1 more source

The employer's perspective: employment of people with disabilities in wage subsidized employments

open access: yesScandinavian Journal of Disability Research, 2013
The aim of this article is to examine employers' perspectives of the conditions of employment of people with disabilities within a context of wage subsidies.
Johanna Gustafsson   +2 more
doaj   +1 more source

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